Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Robert H. Gerner"'
Autor:
Kenneth R. Kaufman, Robert H. Gerner
Publikováno v:
Epilepsy & Behavior. 4:766-770
Rational polypharmacy is required for management of refractory psychiatric disorders. Antiepileptic drugs are increasingly used as primary or adjunctive agents in the treatment of affective, schizoaffective, anxiety, and impulse control disorders. In
Autor:
Robert H. Gerner
Publikováno v:
Psychiatric Clinics of North America. 16:443-460
Treatment of acute mania requires attention to both specific and nonspecific antimanic medications. The choice of specific agents now includes lithium, carbamazepine, and valproate; and nonspecific agents include benzodiazepines, calcium channel bloc
Publikováno v:
Psychiatry Research. 34:315-329
Seasonal variations in cyanoimipramine (CNIMI) sensitive and CNIMI resistant subclasses of platelet 3H-imipramine (3H-IMI) binding sites were studied in depressed patients and normal volunteers. Sinusoidal rhythms of the binding of both subclasses we
Publikováno v:
Psychiatry Research. 34:303-313
A decreased density of platelet 3 H-imipramine ( 3 H-IMI) binding sites has been proposed as a putative trait marker of major depressive illness. However, subsequent studies have demonstrated that the number of such sites is increased so as to be mor
Autor:
Robert H. Gerner, Nicholas Rosenlicht
Publikováno v:
Annals of Clinical Psychiatry. 2:57-65
Approximately 30% to 40% of depressed patients do not respond to an initial trial of antidepressant medication. Most studies indicate that the majority of nonre-sponders have received inadequate pharmacologic treatment. Possible reasons for inadequat
Publikováno v:
Current medical research and opinion. 20(2)
Bipolar disorder greatly impacts health-related quality of life (HRQoL), physical and social functioning, employment, and work productivity, and greatly increases health-care utilization and costs. Our objective was to characterize how bipolar disord
Autor:
Jim Mintz, Jeffery N. Wilkins, George Bartzokis, Tanya Jimenez, Tom Grieder, John Curran, Lori L. Altshuler, Kristin Leight, Robert H. Gerner
Publikováno v:
Biological psychiatry. 48(2)
Background: Hippocampal atrophy has been described in postmortem and magnetic resonance imaging studies of schizophrenia. The specificity of this finding to schizophrenia remains to be determined. The neuropathology of bipolar disorder is understudie
Autor:
Abigail Stanton, Robert H. Gerner
Publikováno v:
Journal of clinical psychopharmacology. 12
Lithium remains the mainstay of pharmacologic therapy for the majority of patients with bipolar disorder; however, significant numbers of patients with both classical bipolar disorder and syndromal variants fail to respond to lithium therapy. The dis
Autor:
Robert H. Gerner, Edward M. DeMet, Christopher Reist, Stacey Warren, Kate M. Bell, Joseph C. Wu, Aleksandra Chicz-DeMet
Publikováno v:
Biological psychiatry. 29(5)
Seasonal cycles of platelet 3H-imipramine binding were compared in 49 endogenous unipolar depressed patients and 20 normal volunteers. A significant sinusoidal component was detected in the Bmax of binding in both patients and controls with similar a