Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Robert H. Diamond"'
Autor:
Bruce Salzberg, Gary R. Lichtenstein, Russell D. Cohen, Robert H. Diamond, William J. Sandborn, Brian G. Feagan, Anil Londhe, Wayne Langholff
Publikováno v:
American Journal of Gastroenterology. 109:212-223
We assessed potential associations between malignancy and antitumor necrosis factor therapy in patients with Crohn's disease (CD), as this relationship is currently poorly defined.Utilizing data from the Crohn's Therapy, Resource, Evaluation, and Ass
Autor:
Michael, Montgomery, Marije M, van Santen, Bart J, Biemond, Robert H, Diamond, Steven T, Pals
Publikováno v:
Gastroenterologyhepatology. 11(3)
Hepatosplenic T-cell lymphoma (HSTCL) is a rare malignancy of unknown incidence that has been associated with immune-mediated disease. This study explored the incidence and patient characteristics of HSTCL in a population of 15.5 million over a 13-ye
Autor:
Jennifer Montello, Freddy Cornillie, Paul Rutgeerts, Robert H. Diamond, William J. Sandborn, Marion Blank, Gary R. Lichtenstein, Linda Tang, Bruce E. Sands, Jean-Frederic Colombel
Publikováno v:
The American Journal of Gastroenterology
OBJECTIVES: The objective of this study was to analyze the safety of long-term infliximab treatment, with/without concomitant immunomodulators, across Crohn's disease (CD) and ulcerative colitis (UC) clinical trials. METHODS: To maximize sample size,
Autor:
C. L. Wagner, Colleen Marano, Jewel Johanns, William J. Sandborn, Adedigbo Fasanmade, Gary R. Lichtenstein, Yinghua Lang, Robert H. Diamond, Allan Olson
Publikováno v:
Alimentary Pharmacology & Therapeutics. 30:210-226
Summary Background Benefits and risks of concomitant immunomodulators and maintenance infliximab in inflammatory bowel disease (IBD) patients have not been adequately evaluated. Aim To assess the effect of concomitant immunomodulator and infliximab m
Autor:
Michelle L. Pritchard, Gary R. Lichtenstein, Brian G. Feagan, Robert H. Diamond, William J. Sandborn, Donny M. Chen, Bruce Salzberg, Russell D. Cohen
Publikováno v:
Clinical Gastroenterology and Hepatology. 4:621-630
Long-term safety data for infliximab and other therapies in Crohn's disease (CD) are needed.We prospectively evaluated patients for prespecified safety-related outcomes.As of August 2004, 6290 patients were enrolled; 3179 received infliximab (5519 pa
Autor:
Robert H. Diamond, Brian G. Feagan, Gary R. Lichtenstein, Suzanne Travers, Stephen B. Hanauer, Allan Olson, Michelle L. Pritchard, William J. Sandborn, Donny M. Chen, Bruce Salzberg, Russell D. Cohen
Publikováno v:
The American Journal of Gastroenterology. 101:1030-1038
Theoretical concern exists that rapid luminal healing in Crohn's disease (CD) with therapies like infliximab increases the risk of intestinal stenosis, stricture, or obstruction (SSOs).Data were analyzed from the ongoing observational TREAT (the Croh
Autor:
Freddy Cornillie, Stephen B. Hanauer, Zhenhua Xu, Paul Rutgeerts, Robert H. Diamond, Kezhen L. Tang, Severine Vermeire, Jianping Wang
Publikováno v:
Gut
Background Serum infliximab trough levels correlate with efficacy; dose escalation is often beneficial in patients with Crohn9s disease who stop responding to infliximab treatment. Objective To carry out a post hoc analysis of A Crohn9s Disease Clini
Publikováno v:
American Journal of Gastroenterology. 105:2299-2301
Hepatosplenic T-Cell Lymphoma in Inflammatory Bowel Disease: A Possible Thiopurine-Induced Chromosomal Abnormality
Publikováno v:
Journal of Biological Chemistry. 274:4513-4520
The cellular signals that initiate cell growth are incompletely understood. Insight could be provided by understanding the signals regulating the transcriptional induction of immediate-early genes which occurs within minutes of the growth stimulus. T
Publikováno v:
Journal of Biological Chemistry. 273:17286-17295
Expression of the rat PRL-1 gene, which encodes a unique nuclear protein tyrosine phosphatase, is positively associated with cellular growth during liver development, regeneration, and oncogenesis but with differentiation in intestine and other tissu