Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Robert H. Perry"'
Autor:
Elaine K. Perry, Mary Johnson, Antigoni Ekonomou, Robert H. Perry, Clive Ballard, Johannes Attems
Publikováno v:
Neurobiology of Disease, Vol 47, Iss 2, Pp 155-162 (2012)
Neurogenesis occurs in the subventricular zone and the sub-granular layer of the hippocampus and is thought to take place in 5 stages, including proliferation, differentiation, migration, targeting, and integration phases, respectively. In Alzheimer'
Externí odkaz:
https://doaj.org/article/72fab968c40745a5a216e7fb6827f028
Autor:
Amanda J. Myers, Alan M. Pittman, Alice S. Zhao, Kristen Rohrer, Mona Kaleem, Lauren Marlowe, Andrew Lees, Doris Leung, Ian G. McKeith, Robert H. Perry, Chris M. Morris, John Q. Trojanowski, Christopher Clark, Jason Karlawish, Steve Arnold, Mark S. Forman, Vivianna Van Deerlin, Rohan de Silva, John Hardy
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 3, Pp 561-570 (2007)
Previously we have shown that the H1c haplotype on the background of the H1 clade of haplotypes at the MAPT locus is associated with increased risk for progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and Alzheimer’s disease (A
Externí odkaz:
https://doaj.org/article/8d634a24426e480a820cfa3b11293a36
Autor:
Cecilia Gotti, Milena Moretti, Iwo Bohr, Iryna Ziabreva, Silvia Vailati, Renato Longhi, Loredana Riganti, Annalisa Gaimarri, Ian G. McKeith, Robert H. Perry, Dag Aarsland, Jan Petter Larsen, Emanuele Sher, Ruth Beattie, Francesco Clementi, Jennifer A. Court
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 2, Pp 481-489 (2006)
Antibodies raised against human α2-6 and β2-4 nicotinic receptor subunits were utilized to fractionate 3H-epibatidine binding in human temporal cortex and striatum. The predominant receptor subtypes in both regions contained α4 and β2 subunits. I
Externí odkaz:
https://doaj.org/article/58d26e8963cd4e5683a49d3e74863539
Autor:
Michael J. Firbank, Yoshiki Hase, Emily Hawthorne, Lucinda J. L. Craggs, Vincent Deramecourt, Tuomo Polvikoski, William Stevenson, Clive Ballard, Charlotte Platten, Raj N. Kalaria, Louise Allan, Roxana O. Carare, Paul G. Ince, Robert H. Perry, Rose Anne Kenny, Karen Horsburgh
Publikováno v:
Hase, Y, Polvikoski, T M, Firbank, M J, Craggs, L J L, Hawthorne, E, Platten, C, Stevenson, W, Deramecourt, V, Ballard, C, Kenny, R A, Perry, R H, Ince, P, Carare, R O, Allan, L M, Horsburgh, K & Kalaria, R N 2020, ' Small vessel disease pathological changes in neurodegenerative and vascular dementias concomitant with autonomic dysfunction ', Brain Pathology, vol. 30, no. 1, pp. 191-202 . https://doi.org/10.1111/bpa.12769
Brain Pathol
Brain Pathol
Autonomic dysfunction may affect brain blood flow and result in intermittent cerebral hypoperfusion, which is recognised as a cause of cognitive impairment and dementia. We assessed the burden of small vessel disease pathology in elderly subjects who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2227d564c576b78fa276f30bcc3d11
https://eprints.whiterose.ac.uk/150702/1/Hase_2019_Brain_Pathology_SVDinAutonomicDisease.pdf
https://eprints.whiterose.ac.uk/150702/1/Hase_2019_Brain_Pathology_SVDinAutonomicDisease.pdf
Autor:
Simon Lovestone, Christine M. Hulette, Philip L. De Jager, Julie A. Schneider, Victor P. Andreev, Lucia I. Sue, Vladislav A. Petyuk, Christopher Morris, Eric E. Schadt, Rui Chang, David A. Bennett, Andrew P. Lieberman, Noam D. Beckmann, Roger L. Albin, Ian G. McKeith, Randall L. Woltjer, Richard D. Smith, Matthew J. Huentelman, John Hardy, Toumy Guettoche, Jennifer Clarke, Thomas G. Beach, Isidre Ferrer, Fang Xie, John F. Ervin, Eric M. Reiman, Kuixi Zhu, Manuel Ramirez-Restrepo, Marc Henrion, Geidy E. Serrano, Robert H. Perry, Paul D. Piehowski, Loida Navarro, Deborah C. Mash, Anzhelika Engel, Amanda J. Myers, Sven Wang
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Our hypothesis is that changes in gene and protein expression are crucial to the development of late-onset Alzheimerrsquo;s disease. Previously we examined how DNA alleles control downstream expression of RNA transcripts and how those relationships a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fbdef70ea6a927e5f3dff488e936dc
http://hdl.handle.net/2445/140358
http://hdl.handle.net/2445/140358
Autor:
Yvonne S Davidson, Robert H. Perry, Stuart Pickering-Brown, Masato Hasegawa, David M. A. Mann, Sara Rollinson, Ian G. McKeith, Evelyn Jaros, Masami Masuda-Suzukake, Timothy D. Griffiths, Andrew C Robinson, David J. Burn, Atik Baborie
Publikováno v:
Neuropathology and Applied Neurobiology. 41:601-612
AIMS: Frontotemporal lobar degeneration (FTLD) and Motor Neuron Disease are linked by the possession of a hexanucleotide repeat expansion in C9ORF72, and both show neuronal cytoplasmic inclusions within cerebellar and hippocampal neurones which are T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::017e99dd16a8299bbb8bdc33ff75d774
https://doi.org/10.1111/nan.12178
https://doi.org/10.1111/nan.12178
Autor:
Eileen H. Bigio, Alexander Gerhard, Yvonne S Davidson, Robert H. Perry, Andrew C Robinson, Anna Richardson, David M. A. Mann, Atik Baborie, Julie S. Snowden, Quan Hu, David Neary, Evelyn Jaros, Nigel J. Cairns, Manjari Mishra
Publikováno v:
Neuropathology and Applied Neurobiology. 39:157-165
Aims:? We aimed to investigate the role of the nuclear carrier and binding proteins, transportin-1 (TRN1) and transportin-2 (TRN2), TATA-binding protein-associated factor 15 (TAF15) and Ewing's Sarcoma protein (EWS) in inclusion body formation in cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e09b66b7eaf61b3bf387695e8c98985
https://doi.org/10.1111/j.1365-2990.2012.01274.x
https://doi.org/10.1111/j.1365-2990.2012.01274.x
Autor:
Robert H. Perry, Elaine K. Perry, Gordon K. Wilcock, Seth Love, Katy A Chalmers, Clive Ballard, Harry V. Vinters
Cholinesterase inhibitors (ChEIs) are widely used for the symptomatic treatment of Alzheimer's disease (AD). In vitro and in animal studies, ChEIs have been shown to influence the processing of Abeta and the phosphorylation of tau, proteins that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9a5b402234807069da5ca9e3feb085
https://doi.org/10.1007/s00415-009-5000-2
https://doi.org/10.1007/s00415-009-5000-2
Autor:
Anthony J. Brookes, Jennie Norrman, Robert H. Perry, Gordon K. Wilcock, C.M. Yates, David St Clair
Genotypes of apolipoprotein E (ApoE) were determined by polymerase-chain reaction (PCR) amplification and restriction-sizing of brain DNA from 39 cases of Lewy body dementia (LBD), 68 senile Alzheimer's disease (AD) patients and 47 neuropathologicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f44d9e69127d9dce3e5cd1a9a8f4df
https://ora.ox.ac.uk/objects/uuid:98566c07-2e2e-4fe9-8263-b72d209e7dc5
https://ora.ox.ac.uk/objects/uuid:98566c07-2e2e-4fe9-8263-b72d209e7dc5