Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Robert H Lipsky"'
Autor:
Mingkuan Lin, Wan Huang, Nadine Kabbani, Mark M Theiss, John F Hamilton, James M Ecklund, Yvette P Conley, Yoram Vodovotz, David Brienza, Amy K Wagner, Emily Robbins, Gwendolyn A Sowa, Robert H Lipsky
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251110 (2021)
The α7 neuronal nicotinic acetylcholine receptors (α7nAChRs) are essential for anti-inflammatory responses. The human-specific CHRFAM7A gene and its 2bp deletion polymorphism (Δ2bp variant) encodes a structurally-deficient α7nAChRs that may impac
Externí odkaz:
https://doaj.org/article/4a386b81cf444528804f9e1a7194413f
Autor:
Kelly A Hamilton, Yue Wang, Sophia M Raefsky, Sean Berkowitz, Ryan Spangler, Caitlin N Suire, Simonetta Camandola, Robert H Lipsky, Mark P Mattson
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196223 (2018)
Bhlhe40 is a transcription factor that is highly expressed in the hippocampus; however, its role in neuronal function is not well understood. Here, we used Bhlhe40 null mice on a congenic C57Bl6/J background (Bhlhe40 KO) to investigate the impact of
Externí odkaz:
https://doaj.org/article/29b6816178af4788abed0fca4328ae15
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Traumatic brain injury (TBI) has reached epidemic proportions worldwide. The consequences of TBI can be severe even with repetitive mild trauma. If death and coma are avoided, the consequences of TBI in the long term typically involve dizziness, slee
Externí odkaz:
https://doaj.org/article/edce5b3f28144b75b17192ba92008c1f
Autor:
Gwendolyn Sowa, Tricia K. Brannan, Robert H. Lipsky, Wan Huang, David M. Brienza, Nadine Kabbani, John F. Hamilton, Mark M. Theiss, James M. Ecklund, Yoram Vodovotz, Yvette P. Conley, Mingkuan Lin, Emily Robbins, Amy K. Wagner
Publikováno v:
Journal of Neurotrauma. 36:3026-3033
The alpha 7 nicotinic acetylcholine receptor, α7 nAChR, plays a central role in regulating inflammatory responses. Previous studies showed that pharmacological inhibitors of α7nAChR have a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012dbad13953a6f668b380e3d612bed8
https://doi.org/10.1089/neu.2018.6200
https://doi.org/10.1089/neu.2018.6200
Autor:
Robert H. Lipsky, Paul M. Foreman, Benedikt W. Burkhardt, Christoph J. Griessenauer, Mohammadali M. Shoja, Mark R. Harrigan, Beverly C. Walters, Winfield S. Fisher, Philipp Hendrix, Sebastian Senger, R. Shane Tubbs, Nilesh A. Vyas
Publikováno v:
Neurosurgical Review. 43:1173-1178
Loss of consciousness (LOC) at presentation with aneurysmal subarachnoid hemorrhage (aSAH) has been associated with early brain injury and poor functional outcome. The impact of LOC on the clinical course after aSAH deserves further exploration. A re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8c6e049fddf3b5b3860388f88c89de
https://doi.org/10.1007/s10143-019-01142-z
https://doi.org/10.1007/s10143-019-01142-z
Publikováno v:
Informatics in Medicine Unlocked, Vol 23, Iss, Pp 100563-(2021)
Multiple Sclerosis (MS) is an inflammatory disorder associated with immune abnormalities in the Central Nervous System (CNS), including an abundance of monocytes in MS lesions. The molecular basis for this cellular response is still poorly understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a043903ba6a043d2160a49c05889b56a
http://www.sciencedirect.com/science/article/pii/S2352914821000538
http://www.sciencedirect.com/science/article/pii/S2352914821000538
Autor:
Mark M. Theiss, Nadine Kabbani, Gwendolyn Sowa, Robert H. Lipsky, Yoram Vodovotz, David M. Brienza, Wan Huang, Mingkuan Lin, John F. Hamilton, James M. Ecklund, Emily Robbins, Amy K. Wagner, Yvette P. Conley
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0251110 (2021)
PLoS ONE, Vol 16, Iss 5, p e0251110 (2021)
The α7 neuronal nicotinic acetylcholine receptors (α7nAChRs) are essential for anti-inflammatory responses. The human-specific CHRFAM7A gene and its 2bp deletion polymorphism (Δ2bp variant) encodes a structurally-deficient α7nAChRs that may impac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691a9610cbba12106813d7384fe641e4
https://pubmed.ncbi.nlm.nih.gov/33956875
https://pubmed.ncbi.nlm.nih.gov/33956875
Autor:
Minkuan Lin, Mohammadali Mohajel Shoja, Nilesh A. Vyas, Mark R. Harrigan, Robert H. Lipsky, Jean-Francois Pittet, Winfield S. Fisher, R. Shane Tubbs, Mali Mathru, Christoph J. Griessenauer, Philipp Hendrix, Paul M. Foreman, Beverly C. Walters
Publikováno v:
World Neurosurgery. 105:672-677
Background Genetic variations of the serine proteinase inhibitor family E member 1 (SERPINE1) gene, which encodes plasminogen activator inhibitor 1, correlate with serum levels of its product and are associated with thrombophilia and coronary atheros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ca16b1ac91f0dbb6a204923147bf6b
https://doi.org/10.1016/j.wneu.2017.05.175
https://doi.org/10.1016/j.wneu.2017.05.175
Autor:
Paul M. Foreman, Mali Mathru, R. Shane Tubbs, Nilesh A. Vyas, Robert H. Lipsky, Beverly C. Walters, Mark R. Harrigan, Minkuan Lin, Philipp Hendrix, Christoph J. Griessenauer, Winfield S. Fisher, Jean-Francois Pittet, Robert M. Starke, Mohammadali Mohajel Shoja
Publikováno v:
World Neurosurgery. 102:253-257
Background and Purpose Aneurysm size is an important risk factor for aneurysm rupture. The pathophysiologic mechanisms underlying aneurysm growth remain poorly understood. Endothelin signaling is critical for cerebrovascular blood flow regulation. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e71156eaf4755c19bc0d391b0b9fd31
https://doi.org/10.1016/j.wneu.2017.03.041
https://doi.org/10.1016/j.wneu.2017.03.041
Autor:
Mali Mathru, Robert H. Lipsky, Mark R. Harrigan, Philipp Hendrix, Beverly C. Walters, R. Shane Tubbs, Winfield S. Fisher, Minkuan Lin, Nilesh A. Vyas, Christoph J. Griessenauer, Paul M. Foreman, Jean-Francois Pittet, Mohammadali Mohajel Shoja
Publikováno v:
World Neurosurgery. 101:514-519
Background and Purpose Nitric oxide is critical in the regulation of cerebral blood flow and smooth muscle proliferation. It is synthesized by 3 nitric oxide synthase (NOS) isoforms: neuronal, inducible, and endothelial NOS (eNOS). Aneurysmal subarac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687939f600f3213f3ba589b49d6097fe
https://doi.org/10.1016/j.wneu.2017.02.062
https://doi.org/10.1016/j.wneu.2017.02.062