Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Robert H, Mealey"'
Autor:
Siddra A Hines, Joshua D Ramsay, Lowell S Kappmeyer, Audrey OT Lau, Kayode K Ojo, Wesley C Van Voorhis, Donald P Knowles, Robert H Mealey
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-11 (2015)
Abstract Background The apicomplexan hemoparasite Theileria equi is a causative agent of equine piroplasmosis, eradicated from the United States in 1988. However, recent outbreaks have sparked renewed interest in treatment options for infected horses
Externí odkaz:
https://doaj.org/article/2c675a75186040cc8f5c20e77b5c4b9e
Autor:
Joshua D Ramsay, Massaro W Ueti, Wendell C Johnson, Glen A Scoles, Donald P Knowles, Robert H Mealey
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76996 (2013)
Theileria equi has a biphasic life cycle in horses, with a period of intraleukocyte development followed by patent erythrocytic parasitemia that causes acute and sometimes fatal hemolytic disease. Unlike Theileria spp. that infect cattle (Theileria p
Externí odkaz:
https://doaj.org/article/33af47e9e0994a4295dbe79c04447868
Publikováno v:
Journal of Virology. 95
Hepacivirus A (also known as nonprimate hepacivirus and equine hepacivirus) is a hepatotropic virus that can cause both transient and persistent infections in horses. The evolution of intrahost viral populations (quasispecies) has not been studied in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae40acd728f8e55ed4879875fcf5705
https://doi.org/10.1128/jvi.01963-20
https://doi.org/10.1128/jvi.01963-20
Autor:
Massaro W Ueti, Robert H Mealey, Lowell S Kappmeyer, Stephen N White, Nancy Kumpula-McWhirter, Angela M Pelzel, Juanita F Grause, Thomas O Bunn, Andy Schwartz, Josie L Traub-Dargatz, Amy Hendrickson, Benjamin Espy, Alan J Guthrie, W Kent Fowler, Donald P Knowles
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44713 (2012)
Arthropod-borne apicomplexan pathogens that cause asymptomatic persistent infections present a significant challenge due to their life-long transmission potential. Although anti-microbials have been used to ameliorate acute disease in animals and hum
Externí odkaz:
https://doaj.org/article/8230b14e55864a94974b73d625106683
Autor:
Lindsay M. Fry, Glen A. Scoles, Darrell Haney, Stephen N. White, Kelly P. Sears, Joana C. Silva, Angela M. Pelzel-McCluskey, David Odongo, Lowell S. Kappmeyer, Robert H. Mealey, Juanita F. Grause, Massaro W. Ueti, David R. Herndon, David A. Schneider, Kyle Tretina, Donald P. Knowles, James B. Munro, L.N. Wise, Marta G. Silva, Richard P. Bishop
Publikováno v:
International Journal for Parasitology. 48:679-690
A novel apicomplexan parasite was serendipitously discovered in horses at the United States – Mexico border. Phylogenetic analysis based on 18S rDNA showed the erythrocyte-infective parasite to be related to, but distinct from, Theileria spp. in Af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de03c6ea3d07089a914ccfb1a7ab1bf
https://doi.org/10.1016/j.ijpara.2018.03.010
https://doi.org/10.1016/j.ijpara.2018.03.010
Autor:
Fernanda Gimenez, Robert H. Mealey, Wesley C. Van Voorhis, Rama Subba Rao Vidadala, Dustin J. Maly, Kayode K. Ojo, Siddra A. Hines, Ryan Evanoff
Publikováno v:
Veterinary Parasitology. 251:90-94
Introduction Theileria equi, an etiologic agent of equine piroplasmosis, is a tick-transmitted hemoprotozoan of the phylum Apicomplexa. Recent outbreaks of piroplasmosis in the United States have renewed interest in safe and effective treatment optio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e57d42c31cc6c6f1d0aa3ba5fadcd8
https://doi.org/10.1016/j.vetpar.2017.12.024
https://doi.org/10.1016/j.vetpar.2017.12.024
Publikováno v:
Virology. 513:108-113
Understanding the dynamics of acute viral infection is crucial for developing strategies to prevent and control infection. In this study, lentiviral dynamics in a host without adaptive immunity were examined in order to determine kinetic parameters o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99776bd3e20ce6f62f1f6af171cfcfa0
https://doi.org/10.1016/j.virol.2017.09.023
https://doi.org/10.1016/j.virol.2017.09.023
Autor:
Andrew Hemphill, Dustin J. Maly, Ethan A. Merritt, Marilyn Parsons, Audrey O.T. Lau, Daniel K. Howe, Ryan Choi, Samuel L.M. Arnold, Erkang Fan, Michael W. Riggs, Robert H. Mealey, Kayode K. Ojo, Matthew A. Hulverson, J. Stone Doggett, Wesley C. Van Voorhis
Publikováno v:
Experimental Parasitology. 180:71-83
Many life-cycle processes in parasites are regulated by protein phosphorylation. Hence, disruption of essential protein kinase function has been explored for therapy of parasitic diseases. However, the difficulty of inhibiting parasite protein kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbc2d83222828e8e0dc9604cff280bc
https://doi.org/10.1016/j.exppara.2017.01.001
https://doi.org/10.1016/j.exppara.2017.01.001
Publikováno v:
Veterinary Parasitology: X, Vol 3, Iss, Pp 100023-(2020)
Buparvaquone and parvaquone are hydroxynaphthoquinone compounds commonly used to treat livestock infected with Theileria species such as T. parva and T. annulata. In many (sub)tropical regions, chromatic changes in medicines can result from extreme e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4d39f631626441c58685b868e1a30f
https://pubmed.ncbi.nlm.nih.gov/34392948
https://pubmed.ncbi.nlm.nih.gov/34392948
Publikováno v:
Equine veterinary journalReferences. 51(6)
Background In racehorses, serum gamma-glutamyltransferase (GGT) activity is positively correlated with cumulative days in training and, when ≥100 IU/L, has been associated with poor performance. The prevalence of increased GGT activity in North Ame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5748de9527ec74784167d5190aada45e
https://pubmed.ncbi.nlm.nih.gov/33314264
https://pubmed.ncbi.nlm.nih.gov/33314264