Zobrazeno 1 - 10
of 382
pro vyhledávání: '"Robert H, Lane"'
Publikováno v:
Physiological Reports, Vol 8, Iss 8, Pp n/a-n/a (2020)
Abstract Adverse maternal environment (AME) and high‐fat diet in early childhood increase the risk of cognitive impairment and depression later in life. Cognitive impairment associates with hippocampal dysfunction. A key regulator of hippocampal fu
Externí odkaz:
https://doaj.org/article/b7cc82a5c3b947dba0dc87e509e60762
Autor:
Justine S. Habibian, Mitra Jefic, Rushita A. Bagchi, Robert H. Lane, Robert A. McKnight, Timothy A. McKinsey, Ron F. Morrison, Bradley S. Ferguson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Adipose tissue inflammation is a central pathological element that regulates obesity-mediated insulin resistance and type II diabetes. Evidence demonstrates that extracellular signal-regulated kinase (ERK 1/2) activation (i.e. phosphorylatio
Externí odkaz:
https://doaj.org/article/c01c36ef8be84d84a14c081f4ea2159f
Publikováno v:
Pediatric Research. 92:1299-1308
An adverse maternal environment (AME) predisposes progeny towards cognitive impairment in humans and mice. Cognitive impairment associates with hippocampal dysfunction. An important regulator of hippocampal function is the hippocampal serotonergic sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5c86831df7f00437b0aa6444e6ebab
https://doi.org/10.1038/s41390-022-01962-8
https://doi.org/10.1038/s41390-022-01962-8
Publikováno v:
Reprod Sci
Sustaining impactful research within the field of perinatal biology requires training and retention of the next generations of physician-scientists and basic-scientists. Professional societies such as the Perinatal Research Society (PRS) have a uniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04684e7b5c0830aac5313f6d711e18d7
https://doi.org/10.1007/s43032-021-00836-4
https://doi.org/10.1007/s43032-021-00836-4
Publikováno v:
Anatomical record (Hoboken, N.J. : 2007)REFERENCES. 306(1)
An adverse maternal environment (AME) and Western diet (WD) in early life predispose offspring toward cognitive impairment in humans and mice. Cognitive impairment associates with hippocampal dysfunction. An important regulator of hippocampal functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b437561adeaa12c238338d63e6719f5f
https://pubmed.ncbi.nlm.nih.gov/35983908
https://pubmed.ncbi.nlm.nih.gov/35983908
Publikováno v:
Nutrients; Volume 15; Issue 9; Pages: 2167
Exposure to adverse early-life environments (AME) increases the incidence of developing adult-onset non-alcoholic fatty liver disease (NAFLD). DNA methylation has been postulated to link AME and late-onset diseases. This study aimed to investigate wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d450d4b1b8600ceaf82dab68d1f400f8
https://doi.org/10.3390/nu15092167
https://doi.org/10.3390/nu15092167
Autor:
Jeremy Alvord, Kurt H. Albertine, Robert A. McKnight, Bohan Xing, Mar Janna Dahl, Robert H. Lane, Xingrao Ke
Publikováno v:
Pediatric Research
Background The brain of chronically ventilated preterm human infants is vulnerable to collateral damage during invasive mechanical ventilation (IMV). Damage is manifest, in part, by learning and memory impairments, which are hippocampal functions. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91708ca7b2cc94cc98165fa03f275691
https://doi.org/10.1038/s41390-020-01305-5
https://doi.org/10.1038/s41390-020-01305-5
Autor:
Amber Majnik, Teresa Michalkiewicz, Brianna Entringer, Xigang Jing, Xingrao Ke, Robert H. Lane, Girija G. Konduri, Pengyuan Liu, Pui Y. Lai, Alison J. Kriegel
Publikováno v:
Physiol Genomics
Background: Fetal growth restriction (FGR) is a major risk factor for bronchopulmonary dysplasia (BPD). Maternal stress and poor diet are linked to FGR. Effect of perinatal stress on lung development remains unknown. Objective: Using a murine model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3aaafa1f962a3ee3845faa4f3613ec
https://doi.org/10.1152/physiolgenomics.00016.2019
https://doi.org/10.1152/physiolgenomics.00016.2019
Autor:
Tianjing Hu, Andrew M. Kidger, Robert H. Lane, Robert A. McKnight, Kimberly M. Demos-Davies, Emma L. Robinson, Stephen M. Keyse, Marcello Rubino, Sara A. Wennersten, Mary C.M. Weiser-Evans, Bradley S Ferguson, Maria A. Cavasin, Timothy A. McKinsey, Matthew S. Stratton, Eva Nozik
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology
Pulmonary hypertension (PH) is associated with structural remodeling of pulmonary arteries (PAs) because of excessive proliferation of fibroblasts, endothelial cells, and smooth muscle cells (SMCs). The peptide hormone angiotensin II (ANG II) contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f1483e2cc281f0b58e1e5bfa2abfca
https://pubmed.ncbi.nlm.nih.gov/34142888
https://pubmed.ncbi.nlm.nih.gov/34142888
Autor:
Qi Fu, Robert H. Lane, Katie A. Fritz, Xingrao Ke, Yi-Wen Huang, Amber Majnik, Paula E. North
Publikováno v:
The Journal of Nutrition
Background The role of an adverse maternal environment (AME) in conjunction with a postweaning Western diet (WD) in the development of nonalcoholic fatty liver disease (NAFLD) in adult offspring has not been explored. Likewise, the molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14d61de617d4f98432178f3840b5326
https://pubmed.ncbi.nlm.nih.gov/34486661
https://pubmed.ncbi.nlm.nih.gov/34486661