Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Robert Gibson Roy"'
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :1079-1084
Treatment of methyl 3β-acetoxy-16α,17α-dimethyl-5α-androst-9(11)-ene-l7-carboxylic acid (1), or 3β-hydroxy-16α,17α-dimethyl-5α-pregn-9(11)-en-20-one (4), with methylmagnesium halide in refluxing anisole gives the 20-yne (3). Similarly 3β-ace
Autor:
Robert Thomas Logan, Gilbert F. Woods, James Cairns, Donald F. M. Stevenson, George Mcgarry, Robert Gibson Roy
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2306-2316
The development of a 21-alkylation reaction which proceeds via the lithium 20(21)-enolate is described and its scope demonstrated by the preparation of a variety of 21-alkylpregnane derivatives. Application of this process to 11β-acetoxy-16α,17α-d
Autor:
Robert Thomas Logan, James Redpath, Robert Gibson Roy, Thomas Sleigh, Raymond C. Craig, Andrew Craig Boyd, David S. Savage, Malcolm M. Campbell, Iain M. Gilbert
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2235
The seven possible 3-amino-2-hydroxy and 2-amino-3-hydroxy isomers of the anti-arrhythmic steroid, 3α-amino-2β-hydroxy-5α-androstan-17-one, were prepared from 5α-androst-2-en-17-one. The intermediate 2α, 3α- and 2β,3β-epoxides and aziridines