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pro vyhledávání: '"Robert Gentiles"'
Autor:
Thomas J. Sowin, Wang Xilu, Steve O’Conner, Lisa A. Hasvold, Wen-Zhen Gu, Hing L. Sham, Jerry Cohen, Gary T. Wang, Robert Gentiles, Haiying Zhang, Charles W. Hutchins, Gerry Sullivan, Weibo Wang, Saul H. Rosenberg
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:153-158
A non-methionine FT inhibitor lead structure ( 1 ) was designed through computer modeling of the peptidomimetic FT inhibitor ABT839. Optimization of this lead resulted in compounds 2e and 2g , with FT IC 50 values of 1.3 and 1.8 nM, GGT IC 50 of 1400
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5053a145b8f757eac55ff7c0f1cfeb04
https://doi.org/10.1016/j.bmcl.2004.10.014
https://doi.org/10.1016/j.bmcl.2004.10.014
