Výsledky vyhledávání - "Robert G. Sitrin"

Positive airway pressure therapy for sleep-disordered breathing confers short-term benefits to patients with spinal cord injury despite widely ranging patterns of use

Autor: Helena Schotland, Robert G. Sitrin, Armando Kurili, Jeanette P. Brown, Gianna M. Rodriguez, Anthony Chiodo, Kristy A. Bauman

Publikováno v: Spinal Cord. 56:777-789

Prospective, cohort study. To evaluate the effectiveness of bi-level positive airway pressure (PAP) therapy and the patterns of use for sleep-disordered breathing (SDB) in individuals with spinal cord injury (SCI). Academic tertiary care center, USA.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d14603e18e3a980aed71320df693824
https://doi.org/10.1038/s41393-018-0077-z

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Sleep disordered breathing in spinal cord injury: A systematic review

Autor: Robert G. Sitrin, Kristy A. Bauman, Anthony Chiodo

Publikováno v: The Journal of Spinal Cord Medicine. 39:374-382

Spinal cord injury commonly results in neuromuscular weakness that impacts respiratory function. This would be expected to be associated with an increased likelihood of sleep-disordered breathing.(1) Understand the incidence and prevalence of sleep d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a486e14b095f67b5918224287271ed9f
https://doi.org/10.1080/10790268.2015.1126449

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Simplified Approach to Diagnosing Sleep-Disordered Breathing and Nocturnal Hypercapnia in Individuals With Spinal Cord Injury

Autor: Armando Kurili, Robert G. Sitrin, Helena Schotland, Kristy A. Bauman, Gianna M. Rodriguez, Anthony Chiodo

Publikováno v: Archives of Physical Medicine and Rehabilitation. 97:363-371

Objective To evaluate a strategy of home-based testing to diagnose sleep-disordered breathing and nocturnal hypercapnia in individuals with spinal cord injury (SCI). Design Case series. Setting Referral center. Participants Adults with C1-T6 SCI (N=8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8d20fa0f06c054e716a8318ffb7083
https://doi.org/10.1016/j.apmr.2015.07.026

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Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through β1-integrin and VEGFR2

Autor: Alvin H. Schmaier, Robert G. Sitrin, Gretchen A. LaRusch, Alona Merkulova, Douglas B. Cines, Fakhri Mahdi, Zia Shariat-Madar

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 305:H305-H320

How single-chain urokinase (ScuPA) mediates angiogenesis is incompletely understood. ScuPA (≥4 nM) induces phosphorylated (p)ERK1/2 (MAPK44 and MAPK42) and pAkt (Ser473) in umbilical vein and dermal microvascular endothelial cells. Activation of pE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf1e4a87bc48a86c82b0facf3a223b2
https://doi.org/10.1152/ajpheart.00110.2013

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FcγRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions

Autor: Robert G. Sitrin, Carlos H. Serezani, Marc Peters-Golden, David M. Aronoff

Publikováno v: Blood. 114:3316-3324

Leukotriene (LT) B4 is generated in response to engagement of the Fcγ receptor (FcγR) and potently contributes to FcγR-mediated antimicrobial functions in pulmonary alveolar macrophages. In this study, we report that the LTB4 receptor leukotriene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35da15f20f1e803b81f61a4e882e74c3
https://doi.org/10.1182/blood-2009-01-199919

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Lipid Raft Compartmentalization of Urokinase Receptor Signaling in Human Neutrophils

Autor: Donna M. Harsh, Pauline M. Pan, Ji-Biao Huang, Howard R. Petty, Robert G. Sitrin, Douglas R. Johnson, R. Alexander Blackwood

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 30:233-241

Urokinase plasminogen activator (uPA) receptors (uPAR) can be engaged for activation signaling either by aggregation or by binding exogenous uPA. These signaling mechanisms require uPAR to associate with two distinct adhesion proteins, L-selectin and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf5637615bc7ada6ef4c93be1b89350
https://doi.org/10.1165/rcmb.2003-0079oc

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Cutting Edge: Evidence for a Signaling Partnership Between Urokinase Receptors (CD87) and L-Selectin (CD62L) in Human Polymorphonuclear Neutrophils

Autor: Pauline M. Pan, Howard R. Petty, R. Alexander Blackwood, Robert G. Sitrin, Jibiao Huang

Publikováno v: The Journal of Immunology. 166:4822-4825

Leukocyte urokinase plasminogen activator receptors (uPARs) cluster at adhesion interfaces and at migratory fronts where they participate in adhesion, chemotaxis, and proteolysis. uPAR aggregation triggers activation signaling even though this glycol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7aaaec642d8a0ef56ce9a0b4217d0a
https://doi.org/10.4049/jimmunol.166.8.4822

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Clustering of Urokinase Receptors (uPAR; CD87) Induces Proinflammatory Signaling in Human Polymorphonuclear Neutrophils

Autor: Hollie A. Harper, Donna M. Harsh, Robert F. Todd, R. Alexander Blackwood, Pauline M. Pan, Robert G. Sitrin

Publikováno v: The Journal of Immunology. 165:3341-3349

Leukocytes use urokinase receptors (uPAR; CD87) in adhesion, migration, and proteolysis of matrix proteins. Typically, uPAR clusters at cell-substratum interfaces, at focal adhesions, and at the leading edges of migrating cells. This study was undert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337f06631f0d12bf7e82041922472fff
https://doi.org/10.4049/jimmunol.165.6.3341

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