Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Robert G. Lloyd"'
Publikováno v:
Development. 148
Andrew Johnson, a pioneer in the development of the amphibian axolotl as a model to study the early stages of metazoan development, died 15th September 2021. Known as ‘AJ’ by his family, and by his friends and colleagues, his older sister Pam ref
Autor:
Toni Taylor, Amy L. Upton, Robert G. Lloyd, Christian J. Rudolph, Juachi U. Dimude, Sarah L Midgley-Smith, Nicole M Forrester
Publikováno v:
Nucleic Acids Research
Chromosome duplication initiates via the assembly of replication forks at defined origins. Forks proceed in opposite directions until they fuse with a converging fork. Recent work highlights that fork fusions are highly choreographed both in pro- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e503b473647e0ec9d6675500447b017
http://bura.brunel.ac.uk/handle/2438/16361
http://bura.brunel.ac.uk/handle/2438/16361
Autor:
David S. Milner, Akeel A. Mahdi, Geoffrey S. Briggs, Amy L. Upton, Jane I. Grove, Robert G. Lloyd, Christian J. Rudolph
Publikováno v:
Nucleic Acids Research
RecG is a DNA translocase encoded by most species of bacteria. The Escherichia coli protein targets branched DNA substrates and drives the unwinding and rewinding of DNA strands. Its ability to remodel replication forks and to genetically interact wi
Publikováno v:
Nature
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Macmillan Publishers Limited. Chromosome duplication normally initiates through the assembly of replication fork complexes at def
Publikováno v:
Nucleic Acids Research
The DNA-binding protein RdgC has been identified as an inhibitor of RecA-mediated homologous recombination in Escherichia coli. In Neisseria species, RdgC also has a role in virulence-associated antigenic variation. We have previously solved the crys
Publikováno v:
DNA Repair. 9:210-223
The RecG protein of Escherichia coli is a double-stranded DNA translocase that unwinds a variety of branched DNAs in vitro, including Holliday junctions, replication forks, D-loops and R-loops. Coupled with the reported pleiotropy of recG mutations,
Publikováno v:
DNA Repair. 8:1434-1443
RecN is a highly conserved, SMC-like protein in bacteria. It plays an important role in the repair of DNA double-strand breaks and is therefore a key factor in maintaining genome integrity. The insolubility of Escherichia coli RecN has limited effort
Autor:
John Atkinson, Chris J. Cadman, Christian J. Rudolph, Ingeborg van Knippenberg, Emma J. Gwynn, Milind Kumar Gupta, Peter B. Moon, Peter McGlynn, Colin P. Guy, Mark S. Dillingham, Akeel A. Mahdi, Robert G. Lloyd
Publikováno v:
Molecular Cell
Summary Nucleoprotein complexes present challenges to genome stability by acting as potent blocks to replication. One attractive model of how such conflicts are resolved is direct targeting of blocked forks by helicases with the ability to displace t
Publikováno v:
Molecular Microbiology
This is an open access article, shared under a Creative Commons licence. Copyright © 2009 The Authors. Little is known about what happens when forks meet to complete DNA replication in any organism. In this study we present data suggesting that the
Publikováno v:
DNA Repair. 7:1589-1602
In dividing cells, the stalling of replication fork complexes by impediments to DNA unwinding or by template imperfections that block synthesis by the polymerase subunits is a serious threat to genomic integrity and cell viability. What happens to st