Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Robert G. Goold"'
Publikováno v:
Journal of Cell Science. 118:993-1005
Recent experiments show that the microtubule-associated protein (MAP) 1B is a major phosphorylation substrate for the serine/threonine kinase glycogen synthase kinase-3beta (GSK-3beta) in differentiating neurons. GSK-3beta phosphorylation of MAP1B ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3ac50adf05e2cd135c348454cc85b4
https://doi.org/10.1242/jcs.01697
https://doi.org/10.1242/jcs.01697
Publikováno v:
Molecular and Cellular Neuroscience. 28:524-534
In pheochromocytoma 12 (PC12) cells and sympathetic neurons, nerve growth factor (NGF) engagement with the tropomyosin-related tyrosine kinase (TrkA) receptor activates the serine/threonine kinase glycogen synthase kinase 3beta (GSK3beta), enabling i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f438fe8ee86121a1ebde7b60f852f186
https://doi.org/10.1016/j.mcn.2004.11.005
https://doi.org/10.1016/j.mcn.2004.11.005
Publikováno v:
Journal of Neurochemistry. 87:935-946
We have recently shown that nerve growth factor (NGF) induces the phosphorylation of the microtubule-associated protein 1B (MAP1B) by activating the serine/threonine kinase glycogen synthase kinase 3β (GSK3β) in a spatio-temporal pattern in PC12 ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff61a54b24ea653967d48d46d252404a
https://doi.org/10.1046/j.1471-4159.2003.02062.x
https://doi.org/10.1046/j.1471-4159.2003.02062.x
Publikováno v:
Journal of Cell Science. 114:4273-4284
In recent studies we have demonstrated that glycogen synthase kinase 3beta (GSK3beta) and its substrate microtubule-associated protein 1B (MAP1B) regulate the microtubule cytoskeleton during axon outgrowth. To further examine the role GSK3beta plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb734e70dfc8b8f465cd29fa1919defa
https://doi.org/10.1242/jcs.114.23.4273
https://doi.org/10.1242/jcs.114.23.4273
Publikováno v:
Journal of Cell Science. 112:3373-3384
We have recently shown that glycogen synthase kinase 3beta (GSK3beta) phosphorylates the microtubule-associated protein (MAP) 1B in an in vitro kinase assay and in cultured cerebellar granule cells. Mapping studies identified a region of MAP1B high i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cad1fbc90cefa53a39ea30d615187c5
https://doi.org/10.1242/jcs.112.19.3373
https://doi.org/10.1242/jcs.112.19.3373
Publikováno v:
European Journal of Neuroscience. 8:235-248
The present study investigated the cellular distribution of a developmentally regulated phosphorylated form of MAP 1B recognized by monoclonal antibody (mAb) 150 in cultures of dorsal root ganglia. The cell soma and the whole axon, when it first appe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a8f764b6d071875cadc4ffe577edb3
https://doi.org/10.1111/j.1460-9568.1996.tb01208.x
https://doi.org/10.1111/j.1460-9568.1996.tb01208.x
Publikováno v:
Biochemical Society Transactions. 32:809-811
One of the earliest hallmarks that distinguish growing axons from dendrites is their growth rate; axons grow faster than dendrites. In vertebrates, where axons are required to grow for considerable distances, particularly in the peripheral nervous sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c85669113fdbd02961c6c2ed52ce666
https://doi.org/10.1042/bst0320809
https://doi.org/10.1042/bst0320809
Autor:
Marianne J U, Novak, Mary G, Sweeney, Abi, Li, Colm, Treacy, Hoskote S, Chandrashekar, Paola, Giunti, Robert G, Goold, Mary B, Davis, Henry, Houlden, Sarah J, Tabrizi
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 25(13)
The purpose of this study was to characterise a novel family with very slowly progressive pure spinocerebellar ataxia (SCA) caused by a deletion in the inositol 1,4,5-triphosphate receptor 1 (ITPR1) gene on chromosome 3. This is a detailed clinical,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88580ba864a05147d604dbcbc3bfa7ca
https://pubmed.ncbi.nlm.nih.gov/20669319
https://pubmed.ncbi.nlm.nih.gov/20669319
MAP1B is a developmentally regulated microtubule-associated phosphoprotein that regulates microtubule dynamics in growing axons and growth cones. We used mass spectrometry to map 28 phosphorylation sites on MAP1B, and selected for further study a put
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55ada434e9fa9fa72a8118a31bb9f5e
https://europepmc.org/articles/PMC2704879/
https://europepmc.org/articles/PMC2704879/
Publikováno v:
Journal of neurochemistry. 87(4)
We have recently shown that nerve growth factor (NGF) induces the phosphorylation of the microtubule-associated protein 1B (MAP1B) by activating the serine/threonine kinase glycogen synthase kinase 3beta (GSK3beta) in a spatio-temporal pattern in PC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8515e520c279a5081ecf59fb5bd5f217
https://pubmed.ncbi.nlm.nih.gov/14622124
https://pubmed.ncbi.nlm.nih.gov/14622124