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pro vyhledávání: '"Robert G. Familiar"'
Autor:
Robert G. Familiar
Publikováno v:
American Journal of Physiology-Legacy Content. 208:776-781
Anesthetized dogs were submitted to conventional bleeding and reinfusion procedures so as to be able to compare vascular pressure gradients in the forelimb during acute hemorrhage with those recorded subsequently during the development of normovolemi
Publikováno v:
Clinical pharmacology and therapeutics. 24(1)
To evaluate the effect of acute histamine H2-receptor blockade on renal function, renal function studies were performed in a control state and after cimetidine. Studies included acid excretion in response to acid loading, bicarbonate reabsorption dur
Publikováno v:
Clinical pharmacology and therapeutics. 23(4)
Ticrynafen, a diuretic-uricosuric also effective as an antihypertensive, was compared in single doses with several other diuretics. Over an 8-hr period, a 250- mg dose exerted natriuretic activity comparable to that of 25 mg of chlorthalidone and 50
Autor:
Donald Pitkin, Fred Alexander, Robert M. Stote, Jeffrey W. Dubb, Paul Actor, Robert G. Familiar, Stephen Ehrlich
Publikováno v:
Clinical pharmacology and therapeutics. 31(4)
The kinetics and renal handling of ceftizoxime were examined after intravenous and intramuscular injection and the effect of probenecid on its excretion was investigated. Peak serum level after 1000 mg IV was 60.5 μg/ml and half-life (t½) was 1.4 h
Autor:
Jeffrey W. Dubb, Fred Alexander, Dianne Tatoian, Robert M. Stote, Nancy L. Allison, Robert G. Familiar
Publikováno v:
The Journal of international medical research. 14(4)
Temelastine is a selective, competitive histamine H1-receptor antagonist which does not penetrate the central nervous system. The effect of varying doses of temelastine was compared in a randomized, double-blind, controlled study by measuring the inh
Publikováno v:
Clinical pharmacology and therapeutics. 13(5)
Eleven patients with maturity-onset diabetes mellitus and 6 normal subjects were studied to determine whether they would develop abnormal serum potassium or glucose levels in response to triamterene, to an acute glucose load, or to an acute glucose l