Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Robert G. Cooke"'
Autor:
Sagar V. Parikh, James L. Kennedy, Robert G. Cooke, Chun Xu, Peter P. Li, Jerry J. Warsh, Marty Green, Bronwen Hughes
Publikováno v:
Bipolar Disorders. 10:105-110
Background: The nuclear-encoded mitochondrial complex I subunit gene, NDUFV2, has been implicated in the pathogenesis of bipolar disorder (BD) in Japanese by virtue of association of variants in its promoter with BD and decreased NDUFV2 messenger rib
Autor:
Sylvain Houle, Robert G. Cooke, Glen B. Baker, Jeffrey H Meyer, Alan A. Wilson, Lina Chiuccariello, Robert D. Levitan, Stephen J Kish, Nathan J. Kolla, Laura Miler, Pablo Rusjan
Publikováno v:
International Journal of Neuropsychopharmacology
Background: Monoamine oxidase inhibitors (MAOIs) are being developed for major depressive disorder, Alzheimer’s, and Parkinson’s Disease. Newer MAOIs have minimal sensitivity to tyramine, but a key limitation for optimizing their development is t
Publikováno v:
The Canadian Journal of Psychiatry. 51:218-225
Objective: To identify the determinants of practice location and of outreach consultation of recently graduated psychiatrists. Methods: We surveyed 153 psychiatrists who graduated from the University of Toronto Department of Psychiatry between Januar
Autor:
William J. Burke, Mustafa M. Husain, Stephen K. Brannan, Mitchel A. Kling, Mark Hyman Rapaport, David Ginsberg, Lauren B. Marangell, John Zajecka, Robert H Howland, Robert G. Cooke, Harold A. Sackeim, Andrew A. Nierenberg, A. John Rush, Mark S. George, Barry R. Rittberg, Sonia M. Davis
Publikováno v:
Biological Psychiatry. 58:347-354
Background Vagus nerve stimulation (VNS) alters both concentrations of neurotransmitters or their metabolites and functional activity of central nervous system regions dysregulated in mood disorders. An open trial has suggested efficacy. Methods This
Autor:
Sagar V. Parikh, James L. Kennedy, Roger S. McIntyre, Bronwen Hughes, Robert G. Cooke, Jerry J. Warsh, Fabio Macciardi, Chun Xu, Peter P. Li, Il Sang Yoon
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :36-43
Disturbed intracellular calcium (Ca(2+)) homeostasis has been implicated in bipolar disorder (BD). Reduced mRNA levels of the transient receptor potential Ca(2+) permeable channel melastatin type 2, TRPM2, in B lymphoblast cell lines (BLCL) from bipo
Publikováno v:
Journal of Affective Disorders. 74:279-285
Background: Catatonic symptoms have been associated with mixed mania in the older psychiatric literature, however, to date no systematic studies have been performed to assess their frequency in these patients. Method: Ninety-nine patients with bipola
Publikováno v:
Psychiatric Rehabilitation Journal. 26:249-261
Finding measures that can assess areas of expected program impact, provide valid results, and be easily integrated into routine program practices is a significant challenge. This paper is intended to assist program staff by providing an accessible in
Autor:
Robert G. Cooke, Sagar V. Parikh, James L. Kennedy, Yoon Is, Jerry J. Warsh, Siu Kp, Peter P. Li
Publikováno v:
Molecular Psychiatry. 6:678-683
Reduced inositol monophosphatase (IMPase) activity and elevated basal intracellular calcium levels ([Ca(2+)](B)) have been reported in B lymphoblast cell lines (BLCLs) from bipolar I affective disorder (BD-I) patients, which may reflect cellular endo
Publikováno v:
Journal of Affective Disorders. 61:81-85
Background : Although bipolar disorder is associated with substantial levels of disability, efforts to investigate the correlates of impairment have been meagre. Methods : Sixty-one euthymic patients with a diagnosis of bipolar disorder were administ
Autor:
Robert G. Cooke, Sagar V. Parikh, Lyanne C. Schlichter, Masoumeh Emamghoreishi, Jerry J. Warsh, Peter P. Li
Publikováno v:
Biological Psychiatry. 48:665-673
Background: Evidence of extensive cross-talk between calcium (Ca 2+ )- and cAMP-mediated signaling systems suggests that previously reported abnormalities in Ca 2+ homeostasis in bipolar I (BP-I) patients may be linked to disturbances in the function