Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robert G Dullea"'
Autor:
Nathanael G Lintner, Kim F McClure, Donna Petersen, Allyn T Londregan, David W Piotrowski, Liuqing Wei, Jun Xiao, Michael Bolt, Paula M Loria, Bruce Maguire, Kieran F Geoghegan, Austin Huang, Tim Rolph, Spiros Liras, Jennifer A Doudna, Robert G Dullea, Jamie H D Cate
Publikováno v:
PLoS Biology, Vol 16, Iss 4, p e1002628 (2018)
[This corrects the article DOI: 10.1371/journal.pbio.2001882.].
Externí odkaz:
https://doaj.org/article/3cb85e619abd466a91199f6643f6fcd9
Autor:
Nathanael G Lintner, Kim F McClure, Donna Petersen, Allyn T Londregan, David W Piotrowski, Liuqing Wei, Jun Xiao, Michael Bolt, Paula M Loria, Bruce Maguire, Kieran F Geoghegan, Austin Huang, Tim Rolph, Spiros Liras, Jennifer A Doudna, Robert G Dullea, Jamie H D Cate
Publikováno v:
PLoS Biology, Vol 15, Iss 3, p e2001882 (2017)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) plays a key role in regulating the levels of plasma low-density lipoprotein cholesterol (LDL-C). Here, we demonstrate that the compound PF-06446846 inhibits translation of PCSK9 by inducing the ri
Externí odkaz:
https://doaj.org/article/c8c20b848f9a4b7e848edcb19074a5c8
Autor:
Lintner, Nathanael G., McClure, Kim F., Petersen, Donna, Londregan, Allyn T., Piotrowski, David W., Wei, Liuqing, Xiao, Jun, Bolt, Michael, Loria, Paula M., Maguire, Bruce, Geoghegan, Kieran F., Huang, Austin, Rolph, Tim, Liras, Spiros, Doudna, Jennifer A., Dullea, Robert G., Cate, Jamie H. D.
Publikováno v:
PLoS Biology. 4/17/2018, Vol. 16 Issue 4, p1-1. 1p.
Liver-Targeted Small-Molecule Inhibitors of Proprotein Convertase Subtilisin/Kexin Type 9 Synthesis.
Autor:
McClure, Kim F.1 kim.f.mcclure@pfizer.com, Piotrowski, David W.1, Petersen, Donna1, Wei, Liuqing1, Xiao, Jun1, Londregan, Allyn T.1, Kamlet, Adam S.1, Dechert‐Schmitt, Anne‐Marie1, Raymer, Brian1, Ruggeri, Roger B.1, Canterbury, Daniel1, Limberakis, Chris1, Liras, Spiros1, DaSilva‐Jardine, Paul, Dullea, Robert G.1, Loria, Paula M.1, Reidich, Benjamin1, Salatto, Christopher T.1, Eng, Heather1, Kimoto, Emi1
Publikováno v:
Angewandte Chemie. 12/18/2017, Vol. 129 Issue 51, p16436-16440. 5p.
Autor:
Lintner, Nathanael G.1, McClure, Kim F.2, Petersen, Donna3, Londregan, Allyn T.4, Piotrowski, David W.4, Wei, Liuqing4, Xiao, Jun4, Bolt, Michael5, Loria, Paula M.3, Maguire, Bruce3, Geoghegan, Kieran F.6, Huang, Austin7, Rolph, Tim8, Liras, Spiros2,4, Doudna, Jennifer A.1,9,10,11,12, Dullea, Robert G.8 robert.dullea@pfizer.com, Cate, Jamie H. D.1,9,10,11 jcate@lbl.gov
Publikováno v:
PLoS Biology. 3/21/2017, Vol. 15 Issue 3, p1-36. 36p.