Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Robert G, Keynes"'
Autor:
Anastasia Karchevskaya, Tomas C. Bellamy, A. W. Edith Chan, David L. Selwood, Robert G. Keynes, Dieter Riddall, Charmaine Griffiths, John Garthwaite
Publikováno v:
Chemical Biology & Drug Design. 94:1680-1693
During some investigations into the mechanism of nitric oxide consumption by brain preparations, several potent inhibitors of this process were identified. Subsequent tests revealed the compounds act by inhibiting lipid peroxidation, a trigger for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a14da4a9f25f9fa1942b18564f7d156d
https://doi.org/10.1111/cbdd.13572
https://doi.org/10.1111/cbdd.13572
Autor:
Robert G, Keynes, Anastasia, Karchevskaya, Dieter, Riddall, Charmaine H, Griffiths, Tomas C, Bellamy, A W Edith, Chan, David L, Selwood, John, Garthwaite
Publikováno v:
Chemical Biology & Drug Design
During some investigations into the mechanism of nitric oxide consumption by brain preparations, several potent inhibitors of this process were identified. Subsequent tests revealed the compounds act by inhibiting lipid peroxidation, a trigger for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23d611e2a97f55d4b56409aea00e08e7
https://pubmed.ncbi.nlm.nih.gov/31127979
https://pubmed.ncbi.nlm.nih.gov/31127979
Publikováno v:
Biochemical Journal. 387:685-694
Mechanisms which inactivate NO (nitric oxide) are probably important in governing the physiological and pathological effects of this ubiquitous signalling molecule. Cells isolated from the cerebellum, a brain region rich in the NO signalling pathway,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e80b15dc1d490bea64ca842c505244
https://doi.org/10.1042/bj20041431
https://doi.org/10.1042/bj20041431
Publikováno v:
European Journal of Neuroscience. 19:1163-1173
Nitric oxide (NO) has been proposed to mediate neurodegeneration arising from NMDA receptor activity, but the issue remains controversial. The hypothesis was re-examined using organotypic slice cultures of rat hippocampus, with steps being taken to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628522a43b5414afbc72900232f17c2f
https://doi.org/10.1111/j.1460-9568.2004.03217.x
https://doi.org/10.1111/j.1460-9568.2004.03217.x
Publikováno v:
Journal of Neuroscience Research. 57:236-243
Recent evidence suggests that the oligodendrocyte cell loss observed in multiple sclerosis sufferers is in part mediated by apoptosis. Here we use a human cell line, MO3.13, as a model system to investigate the biochemical processes involved in oligo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95c6a58ff0390ef5d441684c995aa23e
https://doi.org/10.1002/(sici)1097-4547(19990715)57:2<236::aid-jnr9>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19990715)57:2<236::aid-jnr9>3.0.co
Autor:
Robert G. Keynes, John Garthwaite
Publikováno v:
Current molecular medicine. 4(2)
The role of the neural messenger nitric oxide (NO) in cerebral ischaemia has been investigated extensively in the past decade. NO may play either a protective or destructive role in ischaemia and the literature is plagued with contradictory findings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce3d2224544a46b9c0ce3a560340b67
https://pubmed.ncbi.nlm.nih.gov/15032712
https://pubmed.ncbi.nlm.nih.gov/15032712
Publikováno v:
The Biochemical journal. 369(Pt 2)
NO functions ubiquitously as a biological messenger but has also been implicated in various pathologies, a role supported by many reports that exogenous or endogenous NO can kill cells in tissue culture. In the course of experiments aimed at examinin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515c7eec542f7390966ff4788fc4196d
https://pubmed.ncbi.nlm.nih.gov/12366375
https://pubmed.ncbi.nlm.nih.gov/12366375
Publikováno v:
Biochemical Journal; Apr2009, Vol. 419 Issue 2, p411-418, 8p