Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Robert Fricke"'
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 47:803-815
In vitro and in vivo studies were performed with the novel, selective, nonsteroidal mineralocorticoid receptor antagonist finerenone to assess the relevance of inhibitory effects on the transporters breast cancer resistance protein (BCRP), organic an
Publikováno v:
Journal of Thermophysics and Heat Transfer. 35:512-517
The determination of the ablation rate for thermal protection systems on atmospheric entry is a difficult task, but can have significant implications in terms of safety and heat shield design. Abla...
Autor:
Joachim Höchel, Christian Friedrich, Robert Fricke, Isabella Gashaw, Antje Rottmann, Kai Riecke, Herbert Wiesinger, Bettina Nowotny, Margarete Dr. Brudny-Klöppel, Stefan Klein
Publikováno v:
Clinical Pharmacology and Therapeutics
It is known that co‐administration of CYP3A inducers may decrease the effectiveness of oral contraceptives containing progestins as mono‐preparations or combined with ethinylestradiol. In a randomized clinical drug‐drug interaction study, we in
Autor:
Gary Wilkinson, Robert Fricke, Timo Korjamo, Mikko Koskinen, Olaf Prien, Hille Gieschen, Kristina Graudenz, Karsten Denner, Michaela Bairlein, Clemens-Jeremias Von Bühler, Christian Zurth
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives Darolutamide is a novel androgen receptor (AR) antagonist approved for the treatment of nonmetastatic castration-resistant prostate cancer (nmCRPC). Accordingly, the drug–drug interaction (DDI) potential of darolutamide wa
Publikováno v:
SIGUCCS
The drive for both diversity and Inclusion has become more and more central to the core values of many instructional institutions throughout the world. Until recently, many LGBTQ+ people felt the need to hide who they were. As a somewhat invisible mi
Autor:
Olaf Prien, Iris Kuss, Kristina Graudenz, Karim Fizazi, Bart Ploeger, Gustavo Borghesi, Teuvo L.J. Tammela, Neal D. Shore, Robert Fricke, Jonathan Moss, Hille Gieschen, Oana Petrenciuc, Frank Verholen, Christian Zurth, Mikko Koskinen, Matthew R. Smith
Publikováno v:
Targeted Oncology
Background Darolutamide, an androgen receptor antagonist with a distinct molecular structure, significantly prolonged metastasis-free survival versus placebo in the phase III ARAMIS study in men with nonmetastatic castration-resistant prostate cancer
Autor:
Robert Fricke
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingesch
Autor:
Robert Fricke
Publikováno v:
SIGUCCS
This paper will discuss the process in which I, along with the help of student staff and other full-time staff, developed a program that not only trained our student staff for positions at Whitman College Technology Services (WCTS) but aided them in
Autor:
Avijit Ghosh, Rob Chambers, Susanna Tse, Zhengyin Yan, Mark G. Qian, Stacy Ho, Paul Harradine, Li Di, Caroline A. Lee, Everett J. Perkins, Robert Fricke, Sean Eckley, J. Cory Kalvass, Christopher Breen, Punit Marathe, Maciej J. Zamek-Gliszczynski
Publikováno v:
Journal of pharmaceutical sciences. 106(12)
Regulatory agencies have recently issued drug-drug interaction guidelines, which require determination of plasma protein binding (PPB). To err on the conservative side, the agencies recommend that a 0.01 lower limit of fraction unbound (fu) be used f
Autor:
Robert Fricke, Matthew R. Smith, Kristina Graudenz, Bart Ploeger, Teuvo L.J. Tammela, Mikko Koskinen, Christian Zurth, Olaf Prien, Karim Fizazi, N.D. Shore, Hille Gieschen
Publikováno v:
Annals of Oncology. 30:v350
Background DARO is an androgen receptor antagonist with a distinct molecular structure, which has demonstrated prolonged metastasis-free survival vs placebo (PBO) in the phase 3 ARAMIS study in non-metastatic castration-resistant prostate cancer pati