Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Robert Freije"'
Autor:
Giorgio Bergamini, Jonas Mechtersheimer, Damiano Azzinnari, Hannes Sigrist, Michaela Buerge, Robert Dallmann, Robert Freije, Afroditi Kouraki, Jolanta Opacka-Juffry, Erich Seifritz, Boris Ferger, Tobias Suter, Christopher R. Pryce
Publikováno v:
Neurobiology of Stress, Vol 8, Iss , Pp 42-56 (2018)
Psychosocial stress is a major risk factor for depression, stress leads to peripheral and central immune activation, immune activation is associated with blunted dopamine (DA) neural function, DA function underlies reward interest, and reduced reward
Externí odkaz:
https://doaj.org/article/1e7b6e963a104f5581649a026e735538
Autor:
Tobias Suter, Christopher R. Pryce, Damiano Azzinnari, Hannes Sigrist, Boris Ferger, Giorgio Bergamini, Erich Seifritz, Jonas Mechtersheimer, Robert Dallmann, Michaela Buerge, Alfroditi Kouraki, Jolanta Opacka-Juffry, Robert Freije
Publikováno v:
Neurobiology of Stress
Neurobiology of Stress, Vol 8, Iss, Pp 42-56 (2018)
Neurobiology of Stress, Vol 8, Iss, Pp 42-56 (2018)
Psychosocial stress is a major risk factor for depression, stress leads to peripheral and central immune activation, immune activation is associated with blunted dopamine (DA) neural function, DA function underlies reward interest, and reduced reward
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000df87732332f1e08f694bf15a40883
https://doi.org/10.1016/j.ynstr.2018.01.004
https://doi.org/10.1016/j.ynstr.2018.01.004
Autor:
Amyaouch Bradaia, Heike Deisemann, Larry Park, Simon Gelman, Esther Steidl, Melanie Gleyzes, Ulrike Dijkman, Celia Dominguez, Leticia Toledo-Sherman, Vinod Khetarpal, Outi Kontkanen, Dirk Winkler, Ioana Neagoe, Robert Freije, Mariette Heins, Taneli Heikkinen, Jukka Puoliväli, Robyn M. Javier, Ladislav Mrzljak, Vahri Beaumont, Geoffrey Tombaugh, Kimmo Lehtimäki, Arash Rassoulpour, Ignacio Munoz-Sanjuan, Andreas Ebneth
Publikováno v:
Experimental neurology. 282
Dysregulation of the kynurenine (Kyn) pathway has been associated with the progression of Huntington's disease (HD). In particular, elevated levels of the kynurenine metabolites 3-hydroxy kynurenine (3-OH-Kyn) and quinolinic acid (Quin), have been re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d57b9e5523dde3c9240d7287e850c32
https://pubmed.ncbi.nlm.nih.gov/27163548
https://pubmed.ncbi.nlm.nih.gov/27163548
Publikováno v:
Journal of Proteome Research, 5(5), 1186-1194. NLM (Medline)
An automated inhibitor affinity extraction method for the activity-based enrichment of matrix metalloproteases (MMPs) is presented. Samples containing purified MMP-12 were first extracted at different flow rates in a syringe pump setup, using cartrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af30152c8f831aee99fb21f60859b273
https://doi.org/10.1021/pr050483b
https://doi.org/10.1021/pr050483b
Autor:
Rainer Bischoff, J. Robert Freije
Publikováno v:
Drug discovery today. Technologies. 3(1)
The complexity of most proteomes is too high to obtain a truly comprehensive view of all expressed proteins by any of the current technologies. Prefractionation techniques are thus necessary to dig deeper into the low-abundance region of the proteome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd015d815d3df631e761d14a39509b67
https://pubmed.ncbi.nlm.nih.gov/24980096
https://pubmed.ncbi.nlm.nih.gov/24980096
Autor:
Thomas I. F. H. Cremers, Robert Brendza, Ruth Motter, Robert Freije, Marieke G. C. van der Hart, Isaac Veinbergs, Lisa Yu, Harm Kooijker, Pearl Tanaka, Gunnar Flik
Publikováno v:
Alzheimer's & Dementia. 7
using a sensitive plate based ELISA system (MSD). Results: Unlike gamma secretase inhibitors, which demonstrate a “potency shift" when the concentration of substrate is very high as in systems overexpressing APP (Burton et al 2008), the potency of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::922872bd8679497c205fa2a6bf5df9a9
https://doi.org/10.1016/j.jalz.2011.05.309
https://doi.org/10.1016/j.jalz.2011.05.309
Publikováno v:
Journal of Chromatography A, 1189(1-2), 417-425. ELSEVIER SCIENCE BV
Matrix metalloproteases (MMPs) comprise a family of enzymes that play important roles in mediating angiogenesis, the remodelling of tissues and in cancer metastasis. Consequently, they are attractive targets for therapeutic intervention in chronic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f848f44226ed6ae4f05a7e8d72c84d7
https://pubmed.ncbi.nlm.nih.gov/18001757
https://pubmed.ncbi.nlm.nih.gov/18001757
Autor:
Robert Freije, Jan Bosman, Angelique L. C. T. van Rijswijk, Rainer Bischoff, Theo M. Luider, Peter C. Burgers, Lennard J. M. Dekker
Publikováno v:
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 847(1), 65-69. ELSEVIER SCIENCE BV
Journal of Chromatography B. Analytical Technologies in the Biomedical and Life Sciences, 847(1), 65-69. Elsevier
Journal of Chromatography B. Analytical Technologies in the Biomedical and Life Sciences, 847(1), 65-69. Elsevier
Immunodepletion of high-abundance proteins from serum is a widely used initial step in biomarker discovery studies. In the present work we have investigated the reproducibility of the depletion step by comparing 250 serum samples from prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040beb8c9d84f8c9bc3bf2bd686feede
https://research.rug.nl/en/publications/f5ae50dd-b281-498e-b396-7d82f0f7d485
https://research.rug.nl/en/publications/f5ae50dd-b281-498e-b396-7d82f0f7d485
Publikováno v:
Journal of Proteome Research; May 2006, Vol. 5 Issue: 5 p1186-1194, 9p