Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robert Frauen"'
Autor:
Jost Pott, Annika Kluge, Astrid Rohrbeck, Ashraf Yusuf Rangrez, Norbert Frey, Alexander Bernt, Lucia Sophie Kilian, Robert Frauen, Derk Frank
Publikováno v:
Journal of Molecular and Cellular Cardiology. 129:130-143
Cardiac remodeling is induced by mechanical or humoral stress causing pathological changes to the heart. Here, we aimed at identifying the role of differentially regulated genes upon dynamic mechanical stretch. Microarray of dynamic stretch induced n
Autor:
Phillip Hoppe, Katharina Stiebeling, Samuel Sossalla, Ashraf Yusuf Rangrez, Annika Kluge, Jost Pott, Derk Frank, Robert Frauen, Norbert Frey
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1864:634-644
The present study focuses on the identification of the gene expression profile of neonatal rat cardiomyocytes (NRVCMs) after dynamic mechanical stretch through microarrays of RNA isolated from cells stretched for 2, 6 or 24 h. In this analysis, myelo
Autor:
Hugo A. Katus, Johanne Gantenberg, Derk Frank, Robert Frauen, László Füzesi, Christian Kuhn, Rainer Will, Christiane Hanselmann, Norbert Frey
Publikováno v:
Journal of Molecular and Cellular Cardiology. 49:673-682
To identify new mediators of cardiac hypertrophy, we performed a genome-wide mRNA screen of stretched neonatal rat cardiomyocytes (NRCMs). In addition to known members of the hypertrophic gene program, we found the novel sarcomeric Z-disc LIM protein
Publikováno v:
Cardiac Cytoarchitecture ISBN: 9783319152622
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::742e24d20818f61ed62d4032f410e7d3
https://doi.org/10.1007/978-3-319-15263-9_8
https://doi.org/10.1007/978-3-319-15263-9_8
Autor:
Derk Frank, Robert Frauen, Christiane Hanselmann, Christian Kuhn, Rainer Will, Hugo A Katus, Norbert Frey
Publikováno v:
Circulation. 118
In order to identify new molecular mediators of cardiomyocyte hypertrophy, we performed a genome wide mRNA microarray screen of biomechanically stretched neonatal rat cardiomyocytes (NRCM). We found the novel sarcomeric LIM protein Dyxin/Lmcd1 being