Výsledky vyhledávání - "Robert Francis Kaiko"

Relative Variability in Bioavailability of Oral Controlled-Release Formulations of Oxycodone and Morphine

Autor: Ruth E. Swanton, Robert D. Colucci, G. Thomas, Robert Francis Kaiko

Publikováno v: American Journal of Therapeutics. 8:231-236

A retrospective analysis compared the coefficients of variation associated with the maximum plasma concentration (Cmax) and the extent of absorption (area under the curve [AUC] from 0 hour to the last observation) for oral, controlled-release tablet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9375981fcb1d6c5663658d4e46b83c67
https://doi.org/10.1097/00045391-200107000-00004

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Comparison of controlled-release and immediate-release oxycodone tablets in patients with cancer pain

Autor: Donna S. Zhukovsky, Robert Francis Kaiko, Marc L. Citron, Ronald Kaplan, Barbara J. Buckley, Winston C. V. Parris, Robert F. Reder

Publikováno v: Journal of Clinical Oncology. 16:3230-3237

PURPOSE This study compared the clinical efficacy of oxycodone hydrochloride controlled-release (CR) tablets administered every 12 hours with immediate-release (IR) oxycodone tablets administered four times daily in patients with cancer-related pain.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db00b1af058b1fd6b766a5926559d6b
https://doi.org/10.1200/jco.1998.16.10.3230

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The Use of Controlled-Release Oxycodone for the Treatment of Chronic Cancer Pain

Autor: Marilyn K. Croghan, Ali Khojasteh, Melvin R. Moore, Robert Francis Kaiko, Benjamin W. Johnson, Robert F. Reder, Barbara J. Buckley, Winston C. V. Parris

Publikováno v: Journal of Pain and Symptom Management. 16:205-211

To compare the effectiveness and safety of controlled-release (CR) oxycodone tablets with immediate-release (IR) oxycodone in patients with chronic cancer pain, a multicenter, randomized, double-blind, parallel-group study was performed in 111 patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::663b093b850205a53b44689386ffd5f8
https://doi.org/10.1016/s0885-3924(98)00064-5

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Controlled-Release Morphine Bioavailability (MS Contin® Tablets) in the Presence and Absence of Food

Autor: Carol M. Cronin, Paul Goldenheim, G. Thomas, Harry Lazarus, Robert Francis Kaiko, R. Grandy

Publikováno v: The Hospice Journal. 6:17-30

The bioavailability of a single, orally administered, 30-mg controlled-release morphine tablet (MS Contin Tablet; The Purdue Frederick Company, Norwalk, Conn.) was compared after fasting or a high fat meal in this single dose, randomized, crossover s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c788ea8b17c08a21a18b27f8f95e6ef
https://doi.org/10.1080/0742-969x.1990.11882681

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Efficacy and safety of controlled-release versus immediate-release oxycodone: randomized, double-blind evaluation in patients with chronic back pain

Autor: Peter G. Lacouture, Robert T. Salzman, Jim M. Wild, Roy Fleischmann, Martin E. Hale, Robert Francis Kaiko, Tad Iwan, Ruth Swanton

Publikováno v: The Clinical journal of pain. 15(3)

To compare the efficacy and safety of controlled-release oxycodone given every 12 hours with immediate-release oxycodone given four times daily in patients with persistent back pain.Randomized, double-blind, active-controlled, two-period crossover tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9121d2098cb73fb2778af3446f1772
https://pubmed.ncbi.nlm.nih.gov/10524470

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Controlled-release oxycodone compared with controlled-release morphine in the treatment of cancer pain: a randomized, double-blind, parallel-group study

Autor: Sharon M. Weinstein, Peter T. Silberstein, Robert Francis Kaiko, Robert F. Reder, Linda R. Bressler, Marc L. Citron, Patricia Mucci-LoRusso, Barry S. Berman, Barbara J. Buckley

Publikováno v: European journal of pain (London, England). 2(3)

Controlled-release oral formulations of oxycodone and morphine are both suitable analgesics for moderate to severe pain. They were compared in cancer-pain patients randomized to double-blind treatment with controlled-release oxycodone (n = 48) or con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d4018e67ce157e4074c9eb8e6f1bcf
https://pubmed.ncbi.nlm.nih.gov/15102384

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