Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robert Fournex"'
Autor:
Nicole Bichet, Christophe Chesne, Georges de Sousa, Alain Fautrel, J. Pichon, M. Placidi, G. Lorenzon, C. Melcion, Marc Benicourt, Roger Rahmani, André Cordier, André Guillouzo, Robert Fournex, Françoise Braut, Daniel Gouy, Pascale Vintèzou, H. Hoellinger
Publikováno v:
Alternatives to Laboratory Animals. 21:281-284
A multicentre validation study of the acute in vitro cytotoxicities of 31 liquid or solid chemicals was carried out by six laboratories, using primary rat hepatocyte cultures as a model system. We report here a comparison of neutral red uptake IC50 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c9bdf11cae57bc44e885f924604b94
https://doi.org/10.1177/026119299302100223
https://doi.org/10.1177/026119299302100223
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 7(4)
Rat hepatocytes were cultured on type I collagen-coated porous membranes, in Waxman's modified medium supplemented with very low concentrations of insulin (10(-9)m), glucagon (10(-10)m) and dexamethasone (10(-8)m). Under these experimental conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f079552027982ed512ef34c314fffd7e
https://pubmed.ncbi.nlm.nih.gov/20732233
https://pubmed.ncbi.nlm.nih.gov/20732233
Autor:
Marc Benicourt, H. Hoellinger, Robert Fournex, J. Pichon, F. Braut, Alain Fautrel, P. Vintezou, A.F. Peloux, M. Placidi, Daniel Gouy, R. Lounes, Jean-Paul Cano, Roger Rahmani, C. Melcion, Christophe Chesne, André Cordier, B. Vannier, I. Diarte, G. de Sousa, André Guillouzo, G. Lorenzon, Nicole Bichet
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 5(5-6)
A multicentre validation study of the acute in vitro cytotoxicity of drugs involving six French laboratories from INSERM or pharmaceutical companies has been carried out. Thirty liquid or solid chemicals such as antibiotics, anticancer drugs and solv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb29207d8e2a77f2d940b48f579d250d
https://pubmed.ncbi.nlm.nih.gov/20732074
https://pubmed.ncbi.nlm.nih.gov/20732074
Publikováno v:
Toxicology in Vitro. 4:771-778
The effects of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) were studied at concentrations ranging from 0.17 to 3.52 mm on post-implanted mouse and rat embryos cultured for 48 hr, either in the absence of any metabolic activation system or in the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e99169e8e33992cacd9f492ae11ba50
https://doi.org/10.1016/0887-2333(90)90047-w
https://doi.org/10.1016/0887-2333(90)90047-w
Publikováno v:
Cytopathology : official journal of the British Society for Clinical Cytology. 6(4)
Adult rat hepatocytes were cultured for 15 days on type I collagen-coated permeable membranes in a hormonally defined Waxman's modified medium supplemented with very low concentrations of insulin, glucagon and dexamethasone. Phase contrast examinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98edf90692d0af30c61704ab2850d800
https://pubmed.ncbi.nlm.nih.gov/8520005
https://pubmed.ncbi.nlm.nih.gov/8520005
Publikováno v:
Toxicology. 72(3)
The effects of allopurinol (HPP) at concentrations ranging from 0.33-1.83 mM and of aspirin (ASA) from 0.28-2.22 mM, were studied on the rat whole-embryo culture system. Embryos were explanted at day 10 of gestation and cultured for 48 h, either in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7008541e7382c4786eca3765648cbf0
https://pubmed.ncbi.nlm.nih.gov/1585379
https://pubmed.ncbi.nlm.nih.gov/1585379
Publikováno v:
Chemischer Informationsdienst. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6341a4dbe08850efaa39b4f7467e914
https://doi.org/10.1002/chin.197715208
https://doi.org/10.1002/chin.197715208
Publikováno v:
Chemischer Informationsdienst. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f7bfcdf6135d0772b84c3368ec239ee
https://doi.org/10.1002/chin.197510229
https://doi.org/10.1002/chin.197510229
Publikováno v:
The Antiprogestin Steroid RU 486 and Human Fertility Control ISBN: 9781468412444
RU 486 showed no toxic effects after acute oral administration to mice and rats. Six-month toxicological studies were performed, using rats (15, 25, and 125 mg/kg) and cynomolgus monkeys (5, 15, and 45 mg/kg). Most of the modifications induced by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2a25b818568168d7829d81e2821348
https://doi.org/10.1007/978-1-4684-1242-0_10
https://doi.org/10.1007/978-1-4684-1242-0_10
Autor:
M. Claire, Vesperto Torelli, G. Rousseau, M. Peterfalvi, Annie Michaud, Robert Fournex, Pierre Corvol
Publikováno v:
Biochemical pharmacology. 29(3)
The in vivo pharmacological activity of several spirolactone compounds was tested in rats and compared to their ability to compete for [3H] aldosterone renal binding sites. Spironolactone, ∗ canrenone, dihydrocanrenone and K-canrenoate were all act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fbcddac0da42234bef356ed9a52f90
https://pubmed.ncbi.nlm.nih.gov/7362649
https://pubmed.ncbi.nlm.nih.gov/7362649