Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Robert F. Steinhoff"'
Publikováno v:
CHIMIA, Vol 70, Iss 4 (2016)
The analysis of compounds from single cells is a major challenge in analytical life science. Labeling strategies, for instance fluorescence detection, are well established for measuring proteins with single cell sensitivity, but they mostly fail to d
Externí odkaz:
https://doaj.org/article/846f14e076154091ba2d797a311d396d
Autor:
Renato Zenobi, Florence Vorspan, Angéline Kernalléguen, Franck Saint-Marcoux, Souleiman El Bakhi, Petra S. Dittrich, Anne-Laure Pelissier-Alicot, Georges Leonetti, Simon Bachler, Daniel Lafitte, Robert F. Steinhoff
Publikováno v:
Analytical Chemistry. 90:2302-2309
Because of inhomogeneous matrix-assisted laser desorption/ionization (MALDI) matrix crystallization and laser shot-to-shot variability, quantitation is not generally performed by MALDI mass spectrometry. Here we introduce a high-throughput MALDI meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4826d7c317842eaa1fcdde0e6d82c18c
https://doi.org/10.1021/acs.analchem.7b04693
https://doi.org/10.1021/acs.analchem.7b04693
Publikováno v:
International Journal of Mass Spectrometry. 416:80-89
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is often applied to assess the dispersity and the end groups of synthetic polymers through the addition of cationizing agents. Here we address how these cation adducts are forme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7a0133b98d8822412aa21ca2c113bf0
https://doi.org/10.1016/j.ijms.2016.10.007
https://doi.org/10.1016/j.ijms.2016.10.007
Autor:
Orane Guillaume-Gentil, Tomaso Zambelli, Robert F. Steinhoff, Patrick Kiefer, Rolf Brönnimann, Alfredo J. Ibáñez, Renato Zenobi, Julia A. Vorholt, Livie Dorwling-Carter, Timo Rey
Publikováno v:
Analytical Chemistry. 89:5017-5023
Single-cell metabolite analysis provides valuable information on cellular function and response to external stimuli. While recent advances in mass spectrometry reached the sensitivity required to investigate metabolites in single cells, current metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bf5d57e11c4f039fc768bcfc616fe3
https://doi.org/10.1021/acs.analchem.7b00367
https://doi.org/10.1021/acs.analchem.7b00367
Autor:
Robert F. Steinhoff, Miroslav Soos, Massimo Morbidelli, Daniel J. Karst, Marie R.G. Kopp, Renato Zenobi, Elisa Serra
Publikováno v:
Biotechnology Progress. 33:879-890
Perfusion cell culture processes allow the steady-state culture of mammalian cells at high viable cell density, which is beneficial for overall product yields and homogeneity of product quality in the manufacturing of therapeutic proteins. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecaef59fcbc0e36f3d716730e8cf715
https://doi.org/10.1002/btpr.2421
https://doi.org/10.1002/btpr.2421
Autor:
Jasmin, Krismer, Jens, Sobek, Robert F, Steinhoff, Rolf, Brönnimann, Martin, Pabst, Renato, Zenobi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2064
Mass spectrometry based metabolomics is the highly multiplexed, label-free analysis of small molecules such as metabolites or lipids in biological systems, and thus one of the most direct ways to characterize phenotypes. However, the phenotyping of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7eb06ee6601d29adc57c90088a0a3284
https://pubmed.ncbi.nlm.nih.gov/31565770
https://pubmed.ncbi.nlm.nih.gov/31565770
Autor:
Robert F. Steinhoff, Rolf Brönnimann, Renato Zenobi, Jasmin Krismer, Martin Pabst, Jens Sobek
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998296
Mass spectrometry based metabolomics is the highly multiplexed, label-free analysis of small molecules such as metabolites or lipids in biological systems, and thus one of the most direct ways to characterize phenotypes. However, the phenotyping of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfcc598c293a1ab8ade90f97240b76bb
https://doi.org/10.1007/978-1-4939-9831-9_9
https://doi.org/10.1007/978-1-4939-9831-9_9
Publikováno v:
METABOLOMICS
Metabolomics, 10 (2)
Metabolomics, 10 (2)
Breath is considered to be an easily accessible matrix, whose chemical composition relates to compounds present in blood. Therefore many metabolites are expected in exhaled breath, which may be used in the future for the development of diagnostic met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074ce563f20c4a3be360c2dc0eb5f808
http://doc.rero.ch/record/325338/files/11306_2013_Article_568.pdf
http://doc.rero.ch/record/325338/files/11306_2013_Article_568.pdf
Autor:
Moritz Wolf, Massimo Morbidelli, Jonathan Souquet, Hervé Broly, Renato Zenobi, Joanna Hajduk, Robert F. Steinhoff, Daniel J. Karst
Publikováno v:
Journal of Biotechnology, 302
Journal of Biotechnology, 302
ISSN:0168-1656
ISSN:1389-0352
ISSN:0168-1656
ISSN:1389-0352
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b18f7d00a08897ec307d1a7149a0ad
https://pubmed.ncbi.nlm.nih.gov/31260704
https://pubmed.ncbi.nlm.nih.gov/31260704
Autor:
Andreas Hierlemann, Jasmin Krismer, Gregor W. Schmidt, Marie R.G. Kopp, Daniel J. Karst, Renato Zenobi, Robert F. Steinhoff, Massimo Morbidelli, Martin Pabst, Fabian Steinebach, Alexander Stettler, Miroslav Soos
Publikováno v:
Methods. 104:33-40
Cell culture process monitoring in monoclonal antibody (mAb) production is essential for efficient process development and process optimization. Currently employed online, at line and offline methods for monitoring productivity as well as process rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93344e0f08c1f56adfde0c173d36411
https://doi.org/10.1016/j.ymeth.2015.12.011
https://doi.org/10.1016/j.ymeth.2015.12.011