Výsledky vyhledávání - "Robert F. Li"

Supplementary Figure 2 from CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance

Autor: Jian Jian Li, David R. Gius, Chun-Xu Hai, Andrew T.M. Vaughan, Lun-Quan Sun, Julian Perks, Robert F. Li, Cuihong Jin, Shuaib Juma, Tieqiao Zhang, June X. Zou, Angela Eldridge, Xiaodi Zhang, Lili Qin, Demet Candas, Ming Fan, Rui Liu

The potential phosphorylation motifs of human SIRT3 were predicted by searching the data base using the combination of software Netphos2.0 server and Automotif server

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039a847982e152d067bb0b350179f9a1
https://doi.org/10.1158/1535-7163.22502956

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Supplementary Figure 6 from CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance

Local mice xenograft tumor radiation settings showing the images of xenograft tumors derived from HCT116 cells harboring Thr150/Ser159 mutant or wild type SIRT3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e1bc430dd52bfd2c311723b5fff7b1
https://doi.org/10.1158/1535-7163.22502944.v1

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Supplementary Figure 5 from CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance

Clonogenic survival ability of HCT116 cells via MnSOD activation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca6231f1e6a60deda5a19e11c5676cf
https://doi.org/10.1158/1535-7163.22502947

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Supplementary Figure 3 from CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance

Western blot of mitochondrial acetylated proteins from irradiated MDA-231 or U87 cells harboring wild-type or Thr150/Ser159 mutant SIRT3.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f93f3aa6082bf0aef41417f0065052
https://doi.org/10.1158/1535-7163.22502953

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Supplementary Figure 4 from CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance

MnSOD activity in MCF10A cells harboring mock, wild type or Thr150/Ser159 mutant SIRT3 following irradiation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261fde2ef147b68838c14177b8c3f58a
https://doi.org/10.1158/1535-7163.22502950

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Supplementary Figure 1 from CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance

Western blot analysis of SIRT3 and acetylated mitochondrial proteins of human breast cancer MDA-231 cells and glioblastoma U87 cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368e61b99ac9560e80619c02d4154f4c
https://doi.org/10.1158/1535-7163.22502959

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CDK1-mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance

Autor: Shuaib Juma, Lili Qin, Xiaodi Zhang, Rui Liu, Ming Fan, Cuihong Jin, Andrew T M Vaughan, Julian R Perks, Jian Jian Li, Chun Xu Hai, June X. Zou, Tieqiao Zhang, Robert F. Li, Lun Quan Sun, David Gius, Demet Candas, Angela Eldridge

Publikováno v: Molecular cancer therapeutics, vol 14, iss 9
Liu, R; Fan, M; Candas, D; Qin, L; Zhang, X; Eldridge, A; et al.(2015). CDK1-mediated SIRT3 activation enhances mitochondrial function and tumor radioresistance. Molecular Cancer Therapeutics, 14(9), 2090-2102. doi: 10.1158/1535-7163.MCT-15-0017. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/04s2j0s5

Tumor adaptive resistance to therapeutic radiation remains a barrier for further improvement of local cancer control. SIRT3, a member of the sirtuin family of NAD+-dependent protein deacetylases in mitochondria, promotes metabolic homeostasis through

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b9f4f795174bfd1a07117dea1be70e
https://europepmc.org/articles/PMC4560959/

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CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection

Autor: Rulong Shen, Lili Qin, Gayle E. Woloschak, Andrew T M Vaughan, Ming Fan, Robert F. Li, Jeffrey S. Murley, Jian Jian Li, Demet Candas, David J. Grdina, Yan Shi, Rui Liu, Cuihong Jin, Chung Ling Lu, Larry S. Wu

Publikováno v: Jin, C; Qin, L; Shi, Y; Candas, D; Fan, M; Lu, CL; et al.(2015). CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection. Free Radical Biology and Medicine, 81, 77-87. doi: 10.1016/j.freeradbiomed.2014.12.026. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/9hn5k0f4

© 2015 Elsevier Inc. All rights reserved. Mammalian cells are able to sense environmental oxidative and genotoxic conditions such as the environmental low-dose ionizing radiation (LDIR) present naturally on the earth's surface. The stressed cells th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47e4bbf2f85ddfa48923c6e47c57317
https://escholarship.org/uc/item/9hn5k0f4

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