Zobrazeno 1 - 10
of 457
pro vyhledávání: '"Robert F. Lemanske"'
Autor:
Charles Washington, Matthew Dapas, Arjun Biddanda, Kevin M. Magnaye, Ivy Aneas, Britney A. Helling, Brooke Szczesny, Meher Preethi Boorgula, Margaret A. Taub, Eimear Kenny, Rasika A. Mathias, Kathleen C. Barnes, CAAPA, Gurjit K. Khurana Hershey, Carolyn M. Kercsmar, Jessica D. Gereige, Melanie Makhija, Rebecca S. Gruchalla, Michelle A. Gill, Andrew H. Liu, Deepa Rastogi, William Busse, Peter J. Gergen, Cynthia M. Visness, Diane R. Gold, Tina Hartert, Christine C. Johnson, Robert F. Lemanske, Fernando D. Martinez, Rachel L. Miller, Dennis Ownby, Christine M. Seroogy, Anne L. Wright, Edward M. Zoratti, Leonard B. Bacharier, Meyer Kattan, George T. O’Connor, Robert A. Wood, Marcelo A. Nobrega, Matthew C. Altman, Daniel J. Jackson, James E. Gern, Christopher G. McKennan, Carole Ober
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Asthma is the most common chronic disease in children, occurring at higher frequencies and with more severe disease in children with African ancestry. Methods We tested for association with haplotypes at the most replicated and si
Externí odkaz:
https://doaj.org/article/0d8b1bafd774497eb37ab1773c9c191e
Autor:
Tarunveer S. Ahluwalia, Anders U. Eliasen, Astrid Sevelsted, Casper-Emil T. Pedersen, Jakob Stokholm, Bo Chawes, Jette Bork-Jensen, Niels Grarup, Oluf Pedersen, Torben Hansen, Allan Linneberg, Amitabh Sharma, Scott T. Weiss, Michael D. Evans, Daniel J. Jackson, Andreanne Morin, Karen A. Krogfelt, Susanne Schjørring, Preben B. Mortensen, David M. Hougaard, Jonas Bybjerg-Grauholm, Marie Bækvad-Hansen, Ole Mors, Merete Nordentoft, Anders D. Børglum, Thomas Werge, Esben Agerbo, James E. Gern, Robert F. Lemanske, Carole Ober, Anders G. Pedersen, Hans Bisgaard, Klaus Bønnelykke
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Genetic variants discovered through genome-wide association studies for asthma together account for a small portion of the heritability. Here, the authors identify a possible epistatic relationship between coding variants in FUT2 and ABO, especially
Externí odkaz:
https://doaj.org/article/59f595f1821040ab9ab6a0e9a00cad59
Autor:
Yanjiao Zhou, Daniel Jackson, Leonard B. Bacharier, David Mauger, Homer Boushey, Mario Castro, Juliana Durack, Yvonne Huang, Robert F. Lemanske, Gregory A. Storch, George M. Weinstock, Kristine Wylie, Ronina Covar, Anne M. Fitzpatrick, Wanda Phipatanakul, Rachel G. Robison, Avraham Beigelman
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
How the airway microbiome influences asthma pathophysiology remains unclear. Here, the authors analyse nasal samples of cohort of school-age children with persistent asthma and find that the microbiota’s patterns and composition at time of early lo
Externí odkaz:
https://doaj.org/article/3c7d234b3d824ae79d9cd5e744d0de74
Autor:
James E. Gern, Daniel J. Jackson, Robert F. Lemanske, Christine M. Seroogy, Umberto Tachinardi, Mark Craven, Stephen Y. Hwang, Carol M. Hamilton, Wayne Huggins, George T. O’Connor, Diane R. Gold, Rachel Miller, Meyer Kattan, Christine C. Johnson, Dennis Ownby, Edward M. Zoratti, Robert A. Wood, Cynthia M. Visness, Fernando Martinez, Anne Wright, Susan Lynch, Carole Ober, Gurjit K. Khurana Hershey, Patrick Ryan, Tina Hartert, Leonard B. Bacharier
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Single birth cohort studies have been the basis for many discoveries about early life risk factors for childhood asthma but are limited in scope by sample size and characteristics of the local environment and population. The Child
Externí odkaz:
https://doaj.org/article/0af95cb8d5d54aa39da54d961c12ad8e
Autor:
Patrick H. Ryan, Cole Brokamp, Jeff Blossom, Nathan Lothrop, Rachel L. Miller, Paloma I. Beamer, Cynthia M. Visness, Antonella Zanobetti, Howard Andrews, Leonard B. Bacharier, Tina Hartert, Christine C. Johnson, Dennis Ownby, Robert F. Lemanske, Heike Gibson, Weeberb Requia, Brent Coull, Edward M. Zoratti, Anne L. Wright, Fernando D. Martinez, Christine M. Seroogy, James E. Gern, Diane R. Gold
Publikováno v:
Journal of Clinical and Translational Science, Vol 5 (2021)
Understanding place-based contributors to health requires geographically and culturally diverse study populations, but sharing location data is a significant challenge to multisite studies. Here, we describe a standardized and reproducible method to
Externí odkaz:
https://doaj.org/article/5212730ede9346a980e378b4c109f746
Autor:
Emma E. Thompson, Jessie Nicodemus-Johnson, Kyung Won Kim, James E. Gern, Daniel J. Jackson, Robert F. Lemanske, Carole Ober
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background The changes that occur during puberty have been implicated in susceptibility to a wide range of diseases later in life, many of which are characterized by sex-specific differences in prevalence. Both genetic and environmental fact
Externí odkaz:
https://doaj.org/article/87c7f3952723442893fa3df535cc3427
Autor:
Nathan Schoettler, Eishika Dissanayake, Mark W. Craven, Jeremiah S. Yee, Joshua Eliason, Eric M. Schauberger, Robert F. Lemanske, Carole Ober, James E. Gern
Publikováno v:
Am J Respir Cell Mol Biol
Chromosome 17q12-q21 is the most replicated genetic locus for childhood-onset asthma. Polymorphisms in this locus containing ∼10 genes interact with a variety of environmental exposures in the home and outdoors to modify asthma risk. However, the f
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Autor:
Carole Ober, Chris G McKennan, Kevin M Magnaye, Matthew C Altman, Charles Washington, Catherine Stanhope, Katherine A Naughton, Mario G Rosasco, Leonard B Bacharier, Dean Billheimer, Diane R Gold, Lisa Gress, Tina Hartert, Suzanne Havstad, Gurjit K Khurana Hershey, Brian Hallmark, D Kyle Hogarth, Daniel J Jackson, Christine C Johnson, Meyer Kattan, Robert F Lemanske, Susan V Lynch, Eneida A Mendonca, Rachel L Miller, Edward T Naureckas, George T O'Connor, Christine M Seroogy, Ganesa Wegienka, Steven R White, Robert A Wood, Anne L Wright, Edward M Zoratti, Fernando D Martinez, Dennis Ownby, Dan L Nicolae, Albert M Levin, James E Gern, Niek Achten, John Ainsworth, Nonna Akkerman, Elizabeth Anderson, Larry J. Anderson, Howard Andrews, Elizabeth Armagost, Mary Ann Aubuchon, Julia Bach, Leonard Bacharier, Kathrine L. Barnes, Charles Barone, Irma Bauer, Paloma Beamer, Patrice Becker, Alyssa Bednarek, Stacey Bellemore, Casper G. Bendixsen, Jocelyn M. Biagini Myers, Christine Billstrand, Geraldine Birg, Shirley Blocki, Gordon Bloomberg, Kevin Bobbitt, Yury Bochkov, Karen Bourgeois, Homer Boushey, Rebecca Brockman-Schneider, Steven M. Brunwasser, Richard Budrevich, Jeffrey W. Burkle, William Busse, Agustin Calatroni, Janice Campbell, Kirsten Carlson-Dakes, Andrea Cassidy-Bushrow, James D. Chappell, Deborah Chasman, Teresa M. Chipps, Tatiana Chirkova, Deanna Cole, Alexandra Connolly, Michelle Cootauco, Kaitlin Costello, Philip Couch, Brent Coull, Mark Craven, Gina Crisafi, William Cruikshank, Kristi Curtsinger, Adnan Custovic, Suman R. Das, Douglas DaSilva, Soma Datta, Brent Davidson, Lydia De La Ossa, Mark DeVries, Qian Di, Samara Dixon, Erin Donnerbauer, Marian Dorst, Susan Doyle, Amy Dresen, William D. Dupont, Janet Durrange, Heidi Erickson, Michael D. Evans, Jerel Ezell, Leanna Farnham, Roxanne Filardo-Collins, Salvatore Finazzo, Zachary Flege, Conner Fleurat, Heather Floerke, Dorothy Floerke, Terry Foss, Angela Freie, Wayne Frome, Samantha Fye, Lisa Gagalis, Rebecca Gammell, Ronald E. Gangnon, James E. Ge, Tebeb Gebretsadik, Peter Gergen, James E. Gern, Heike Gibson, Edlira Gjerasi, Diane R. Gold, Nicole Gonzalez, Kayla Goodman, Kristine Grindle, Taylor Groeschen, Marilyn Halonen, Jaime Hart, Tina V. Hartert, Patrick Heinritz, Sharon Hensley Alford, Julie Herbstman, Kellie Hernandez, Lori Hoepner, Daniel J. Jackson, Samadhan J. Jadhao, Katy Jaffee, Peter James, Jacqueline Jezioro, Marcia Jimenez Pescador, Christine C. Johnson, Tara Johnson, Camille Johnson, Amelia Jones, Kyra Jones, Paul Jones, Carolina Jordan, Christine LM Joseph, Kristina Keidel, Matthew C. Keifer, Rick Kelley, Gurgit K. Khurana Hershey, Haejin Kim, Itai Kloog, Tammy Kronenwetter Koepel, Clint Koerkenmeier, Laura Ladick, Carin Lamm, Emma Larkin, Howard Lederman, Aviva Lee-Parritz, Stephanie Leimenstoll, Robert F. Lemanske, Jr., Grace K. LeMasters, Albert M. Levin, Jessica Levine, Xinhua Liu, Zhouwen Liu, Silvia Lopez, Nathan Lothrop, Stephanie Lovinsky-Desir, Nicholas Lukacs, Susan Lynch, Christian Lynch, Erik Mann, Jennifer Martin, Lisa Martin, Fernando D. Martinez, Elizabeth Matsui, Katherine McCauley, Megan Mccollum, Judith McCullough, Chris G. McKennon, Jennifer Meece, Eneida Mendonca, Lance Mikus, Rachel L. Miller, Patricia Minton, Herman Mitchell, Vicki Moon, Paul E. Moore, Wayne Morgan, Valerie Morgan, David Morgan, Liza Murrison, Charlotte Nicholas, Daniel Nicolae, Adam Nunez, George O'Connor, Sharon O'Toole, Brent F. Olson, Irene Ong, Sarah Osmundson, Tressa Pappas, Frederica Perera, Matthew Perzanowski, Edward Peterson, Marcela Pierce, Penny Price-Johnson, Victoria Rajamanickam, Judyth Ramirez, Kimberly Ray, Megan Renneberg, Weeberb Requia, Kylie Riley, Janelle Rivera, Neisha Rivers, Kathy Roberg, Theresa Rogers, Christian Rosas-Salazar, Pat Russell, Patrick H. Ryan, Yoel Sadovsky, Lisa Salazar, Hugh Sampson, Megan Sandel, Nathan Schoettler, Joel Schwartz, Dena Scott, Christine M. Seroogy, Renee Sharp, Meghan H. Shilts, Steve Sigelman, Anne Marie Singh, Alexandra Sitarik, Ernestine Smartt, Ronald Sorkness, Christine Sorkness, Amber Spangenberg, Rhoda Sperling, David Spies, Debra A. Stern, Brandy Stoffel, R. Stokes Peebles, Gina Stouffer, Cathey Strauchman Boyer, Caitlin Suddeuth, Umberto Tachinardi, Deliang Tang, Zhengzheng Tang, Jena Tate, William Taylor, Krista Tensing, Elizabeth Tesson, Kathy Thompson, Emma Thompson, Christopher Tisler, Alkis Togias, Kedir Turi, Victoria Turner, Marina Tuzova, Jeffrey J. VanWormer, Cynthia M. Visness, Rose Vrtis, Anthony Wahlman, Lena Wang, Karen Wells, William Wentworth-Sheilds, Lisa Wheatley, Nitsa Whitney, L. Keoki Williams, Frank Witter, Christopher Wolfe, Robert A. Wood, Kimberley Woodcroft, Kim B. Woodward, Anne L. Wright, Rosalind Wright, Pingsheng Wu, Melissa Yaeger, Perri Yaniv, Antonella Zanobetti, Shirley Zhang, Patricia Zook, Edward M. Zoratti
Publikováno v:
lancet. Respiratory medicine, 8(5), 482-492. Elsevier Limited
Background: African ancestry is associated with a higher prevalence and greater severity of asthma than European ancestries, yet genetic studies of the most common locus associated with childhood-onset asthma, 17q12–21, in African Americans have be
Autor:
Tebeb Gebretsadik, Brittney D. Snyder, Chang Yu, Echo-Crew investigators, Robert F. Lemanske, Daniel J. Jackson, Kathyrn McCauley, Suzanne Havstad, Christine M. Seroogy, Kedir N. Turi, Susan V. Lynch, Tina V. Hartert, Christopher McKennan, Edward M. Zoratti, Carole Ober, James E. Gern
Publikováno v:
Journal of Allergy and Clinical Immunology. 148:128-138
Background Wheeze and allergic sensitization are the strongest early-life predictors of childhood asthma development; the molecular origins of these early-life phenotypes are poorly understood. Objectives We sought to identify metabolites associated