Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Robert F. Cressman"'
Autor:
Weiqing Zeng, Patrick Garcia, Natalie N. Weber, Cathy X. Zhong, Kevin L. Stecca, Chok-Fun Chui, Knut Meyer, James A. Mickelson, Robert F. Cressman, Bonnie Hong, Cheri W. Tyree, Kent Brink, Nancy Henderson, Carl A. Maxwell
Publikováno v:
Crop Science. 54:2160-2174
Publikováno v:
Regulatory Toxicology and Pharmacology. 67:232-239
Genetically modified crops are becoming important components of a sustainable food supply and must be brought to market efficiently while also safeguarding the public from cross-reactivity of novel proteins to known allergens. Bioinformatic assessmen
Autor:
Cathy X. Zhong, Gregory S. Ladics, Shiping Zhang, Robert F. Cressman, Henry P. Mirsky, Bin Cong, Gregory J. Young
Publikováno v:
Food and Chemical Toxicology. 50(10):3741-3751
Before a genetically modified (GM) crop can be commercialized it must pass through a rigorous regulatory process to verify that it is safe for human and animal consumption, and to the environment. One particular area of focus is the potential introdu
Autor:
Gregory S. Ladics, Laura Privalle, Jason M. Ward, Robert F. Cressman, Ping Song, Scott McClain, Corinne Herouet-Guicheney, Rod A. Herman
Publikováno v:
Regulatory Toxicology and Pharmacology. 60:46-53
Bioinformatic tools are being increasingly utilized to evaluate the degree of similarity between a novel protein and known allergens within the context of a larger allergy safety assessment process. Importantly, bioinformatics is not a predictive ana
Autor:
Jean Schmidt, Gabrielle Carlson, S. Ballou, J.F. Barnett, Bryan Delaney, L.M. Appenzeller, Raymond Layton, Carey A. Mathesius, Gregory S. Ladics, John Zhang, J. Ding, Robert F. Cressman, Carol Carpenter
Publikováno v:
Regulatory Toxicology and Pharmacology. 55:309-320
Acetolactate synthase (ALS) enzymes have been isolated from numerous organisms including soybeans (Glycine max; GM-ALS) and catalyze the first common step in biosynthesis of branched chain amino acids. Expression of an ALS protein (GM-HRA) with two a
Autor:
John Zhang, Gabrielle Carlson, Brad Comstock, Barb Stagg, Amy Babb, Jean Schmidt, Youngshin Han, Bryan Delaney, Dan Siehl, Robert F. Cressman, Greg Ladics, Hugh A. Sampson, Carol Finlay, Luda Bardina, Amarin Cogburn
Publikováno v:
Toxicological Sciences. 102:425-432
The glyphosate acetyltransferase (gat) gene from Bacillus licheniformis was subjected to multiple rounds of gene shuffling to optimize kinetics of corresponding GAT proteins to acetylate the herbicide active ingredient glyphosate. Genetically modifie
Autor:
Mark Holliday, Susan Knowlton, Phyllis Biddle, Richard Broglie, Ilan Chet, Karen Brogue, C. Jeffry Mauvais, Robert F. Cressman
Publikováno v:
Science. 254:1194-1197
The production of enzymes capable of degrading the cell walls of invading phytopathogenic fungi is an important component of the defense response of plants. The timing of this natural host defense mechanism was modified to produce fungal-resistant pl
Autor:
Robert F. Cressman, Gregory S. Ladics
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 54
FAO/WHO has recommended that IgE cross-reactivity between a transgenic protein and allergen be considered when there is greater than 35% identity over a sliding "window" of 80 amino acids. In a previous work, we evaluated the false positive and negat
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 44(2)
Cry1F protein, derived from Bacillus thuringiensis, is effective at controlling lepidopteran pests and a synthetic Cry1F transgene was transferred into maize. For the safety assessment of genetically modified food crops, the allergenic potential of t
Autor:
Robert F. Cressman, Richard Broglie, Ilan Chet, Karen E. Broglie, Phyllis Biddle, Dominique Roby
Publikováno v:
The Plant Cell. 2:999
The temporal and spatial expression of a bean chitinase promoter has been investigated in response to fungal attack. Analysis of transgenic tobacco plants containing a chimeric gene composed of a 1.7-kilobase fragment carrying the chitinase 5B gene p