Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Robert F. Berman"'
Autor:
Jared J. Schwartzer, Dolores Garcia-Arocena, Amanda Jamal, Ali Izadi, Rob Willemsen, Robert F. Berman
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Carriers of the fragile X premutation (PM) can develop a variety of early neurological symptoms, including depression, anxiety and cognitive impairment as well as being at risk for developing the late-onset fragile X-associated tremor/ataxia syndrome
Externí odkaz:
https://doaj.org/article/bda62a518b2245d3a407aa50d122b8e5
Autor:
H. Jürgen Wenzel, Karl D. Murray, Saif N. Haify, Michael R. Hunsaker, Jared J. Schwartzer, Kyoungmi Kim, Albert R. La Spada, Bryce L. Sopher, Paul J. Hagerman, Christopher Raske, Lies-Anne W.F.M. Severijnen, Rob Willemsen, Renate K. Hukema, Robert F. Berman
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-22 (2019)
Abstract The fragile X premutation is a CGG trinucleotide repeat expansion between 55 and 200 repeats in the 5′-untranslated region of the fragile X mental retardation 1 (FMR1) gene. Human carriers of the premutation allele are at risk of developin
Externí odkaz:
https://doaj.org/article/4134f0078ae64270bd17af8e8378a6cd
Autor:
Matthew R. Bruce, Amalie C. M. Couch, Simone Grant, Janna McLellan, Katherine Ku, Christina Chang, Angelica Bachman, Matthew Matson, Robert F. Berman, Richard J. Maddock, Douglas Rowland, Eugene Kim, Matthew D. Ponzini, Danielle Harvey, Sandra L. Taylor, Anthony C. Vernon, Melissa D. Bauman, Judy Van de Water
Publikováno v:
Molecular Psychiatry.
Maternal immune dysregulation is a prenatal risk factor for autism spectrum disorder (ASD). Importantly, a clinically relevant connection exists between inflammation and metabolic stress that can result in aberrant cytokine signaling and autoimmunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3dce4502565b70fc4ac4b5bfe05e41b
https://doi.org/10.1038/s41380-023-02020-3
https://doi.org/10.1038/s41380-023-02020-3
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158150 (2016)
The laboratory rat is emerging as an attractive preclinical animal model of autism spectrum disorder (ASD), allowing investigators to explore genetic, environmental and pharmacological manipulations in a species exhibiting complex, reciprocal social
Externí odkaz:
https://doaj.org/article/51948a6174934b60b8ac1561c0734ee9
Autor:
Amanda L. Jamal, Tara L. Walker, Amanda J. Waber Nguyen, Robert F. Berman, Gerd Kempermann, Ben Waldau M.D.
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Cyclin D2 knockout mice show decreased levels of endogenous dentate neurogenesis. We investigated whether transplanted dentate progenitor cells from wild-type mice respond in vivo to an enriched environment and whether they improve deficient dentate
Externí odkaz:
https://doaj.org/article/dbb5f8ffad154e87a1fbb36c480df582
Autor:
Berit Powers, Albee Messing, Ahmed F. Mohamed, Tracy L. Hagemann, Curt Mazur, Robert F. Berman, Seth C. Hannah, Ni-Hsuan Lin, Katerina L. Dague, Mel B. Feany, Abby L. Olsen, Frank Rigo, Ming-Der Perng, Gemma Bachmann
Publikováno v:
Sci Transl Med
Science translational medicine, vol 13, iss 620
Science translational medicine, vol 13, iss 620
Alexander disease (AxD) is a devastating leukodystrophy caused by gain-of-function mutations in GFAP, and the only available treatments are supportive. Recent advances in antisense oligonucleotide (ASO) therapy have demonstrated that transcript targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695a1c30f14b60e0d9ba759d412cd1d1
https://pubmed.ncbi.nlm.nih.gov/34788075
https://pubmed.ncbi.nlm.nih.gov/34788075
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94475 (2014)
BACKGROUND:Increased rates of autoinflammatory and autoimmune disorders have been observed in female premutation carriers of CGG repeat expansion alleles of between 55-200 repeats in the fragile X mental retardation 1 (FMR1) gene. To determine whethe
Externí odkaz:
https://doaj.org/article/d2c71af971cf4866bf282dc9288e59f7
Autor:
Taryn Morningstar, Joanne Chan, Verónica Martínez-Cerdeño, Zachary Rabow, Megan R. Showalter, Evgeny Nudler, David Zagzag, Sili Fan, Robert F. Berman, Krista Thongphanh, Hailey Heil, Mirna Lechpammer, Oliver Fiehn
Publikováno v:
Brain and behavior, vol 11, iss 5
Brain and Behavior, Vol 11, Iss 5, Pp n/a-n/a (2021)
Brain and Behavior
Brain and Behavior, Vol 11, Iss 5, Pp n/a-n/a (2021)
Brain and Behavior
Introduction Dimethyl sulfoxide (DMSO) is a widely used solvent to dissolve hydrophobic substances for clinical uses and experimental in vivo purposes. While usually regarded safe, our prior studies suggest changes to behavior following DMSO exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8023e5c51db8f0801768d33de5c89283
https://escholarship.org/uc/item/36j50149
https://escholarship.org/uc/item/36j50149
Autor:
Seth C. Hannah, Katerina L. Dague, Mel B. Feany, Curt Mazur, Albee Messing, Ming-Der Perng, Ni-Hsuan Lin, Tracy L. Hagemann, Robert F. Berman, Frank Rigo, Ahmed F. Mohamed, Berit Powers
Alexander disease (AxD) is a devastating leukodystrophy caused by gain of function mutations in GFAP, and the only available treatments are supportive. Recent advances in antisense oligonucleotide (ASO) therapy have demonstrated that transcript targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31e58dfb7a051c6d38c100e09d9ba8ca
https://doi.org/10.1101/2021.01.29.428244
https://doi.org/10.1101/2021.01.29.428244
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38911 (2012)
Misoprostol is a synthetic analogue of prostaglandin E1 that is administered to women at high doses to induce uterine contractions for early pregnancy termination and at low doses to aid in cervical priming during labor. Because of the known teratoge
Externí odkaz:
https://doaj.org/article/49dd0b5b430f43cfbdb251d5f0eae0f6