Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Robert F Schwabe"'
Autor:
Harrison T. Muturi, Hilda E. Ghadieh, Suman Asalla, Sumona G. Lester, Getachew D. Belew, Sobia Zaidi, Raziyeh Abdolahipour, Abhishek P. Shrestha, Agnes O. Portuphy, Hannah L. Stankus, Raghd Abu Helal, Stefaan Verhulst, Sergio Duarte, Ali Zarrinpar, Leo A. van Grunsven, Scott L. Friedman, Robert F. Schwabe, Terry D. Hinds, Jr., Sivarajan Kumarasamy, Sonia M. Najjar
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102010- (2024)
Objectives: Hepatic CEACAM1 expression declines with advanced hepatic fibrosis stage in patients with metabolic dysfunction-associated steatohepatitis (MASH). Global and hepatocyte-specific deletions of Ceacam1 impair insulin clearance to cause hepat
Externí odkaz:
https://doaj.org/article/e69d9f2f8521498ea5cb94a3c6b0d26c
Autor:
Kristin Boggs, Nandakumar Venkatesan, Ingmar Mederacke, Yoshihiro Komatsu, Steve Stice, Robert F Schwabe, Charlotte M Mistretta, Yuji Mishina, Hong-Xiang Liu
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146475 (2016)
Taste buds, the sensory organs for taste, have been described as arising solely from the surrounding epithelium, which is in distinction from other sensory receptors that are known to originate from neural precursors, i.e., neural ectoderm that inclu
Externí odkaz:
https://doaj.org/article/92d80e4f63c74be78cd539ca7a74c859
Autor:
Sören V Siegmund, Monika Schlosser, Frank A Schildberg, Ekihiro Seki, Samuele De Minicis, Hiroshi Uchinami, Christian Kuntzen, Percy A Knolle, Christian P Strassburg, Robert F Schwabe
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150893 (2016)
Serum amyloid A (SAA) is an evolutionary highly conserved acute phase protein that is predominantly secreted by hepatocytes. However, its role in liver injury and fibrogenesis has not been elucidated so far. In this study, we determined the effects o
Externí odkaz:
https://doaj.org/article/57b39f380dc549c4b6086d463d47b92f
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158819 (2016)
The development of hepatocellular carcinoma (HCC) is a common consequence of advanced liver fibrosis but the interactions between fibrogenesis and carcinogenesis are still poorly understood. Recently it has been shown that HCC promotion depends on To
Externí odkaz:
https://doaj.org/article/1820f17f3b7f45aeba9b991542323bf4
Autor:
Wenxin Yu, Maria Eleni Kastriti, Mohamed Ishan, Saurav Kumar Choudhary, Md Mamunur Rashid, Naomi Kramer, Hy Gia Truong Do, Zhonghou Wang, Ting Xu, Robert F. Schwabe, Kaixiong Ye, Igor Adameyko, Hong-Xiang Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionWe have recently demonstrated that Sox10-expressing (Sox10+) cells give rise to mainly type-III neuronal taste bud cells that are responsible for sour and salt taste. The two tissue compartments containing Sox10+ cells in the surrounding
Externí odkaz:
https://doaj.org/article/ff875960f60a40848043ca42d5cf8e6c
Autor:
Kristy St. Rose, Jun Yan, Fangxi Xu, Jasmine Williams, Virginia Dweck, Deepak Saxena, Robert F. Schwabe, Jorge Matias Caviglia
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2676-2688 (2022)
Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the United States and the world; with no Food and Drug Administration–approved pharmacological treatment available, it remains an area of unmet medical need. In n
Externí odkaz:
https://doaj.org/article/b957447ab14e4d74a8ccfd5198291ba5
Autor:
Asmita Choudhury, Anuradha Ratna, Arlene Lim, Rebecca M. Sebastian, Christopher L. Moore, Aveline A. Filliol, Jacob Bledsoe, Chengkai Dai, Robert F. Schwabe, Matthew D. Shoulders, Pranoti Mandrekar
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2781-2797 (2022)
Abstract Liver fibrosis is an aberrant wound healing response that results from chronic injury and is mediated by hepatocellular death and activation of hepatic stellate cells (HSCs). While induction of oxidative stress is well established in fibroti
Externí odkaz:
https://doaj.org/article/e0da366ac2af47d0911440f53019b5d4
Autor:
Annika Volmari, Katharina Foelsch, Elisabeth Zierz, Karsten Yan, Minyue Qi, Karlotta Bartels, Stephanie Kondratowicz, Marius Boettcher, Daniel Reimers, Masahiro Nishibori, Keyue Liu, Robert F. Schwabe, Ansgar W. Lohse, Samuel Huber, Hans‐Willi Mittruecker, Peter Huebener
Publikováno v:
Hepatology Communications, Vol 5, Iss 12, Pp 2104-2120 (2021)
High‐mobility group box 1 (HMGB1) is a nucleoprotein with proinflammatory functions following cellular release during tissue damage. Moreover, antibody‐mediated HMGB1 neutralization alleviates lipopolysaccharide (LPS)‐induced shock, suggesting
Externí odkaz:
https://doaj.org/article/e8ddfffaf1494235a97e00fc6451d930
Publikováno v:
JHEP Reports, Vol 4, Iss 8, Pp 100524- (2022)
Summary: Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions, with a global prevalence of 25% in the adult population. Non-alcoholic steatohepatitis (NASH), which can lead to cirrhosis, has become the leading indication for liv
Externí odkaz:
https://doaj.org/article/9c6f79f6889f4202a4b96f1b3ad550e1
Autor:
Yoshinobu Saito, Dingzi Yin, Naoto Kubota, Xiaobo Wang, Aveline Filliol, Helen Remotti, Ajay Nair, Ladan Fazlollahi, Yujin Hoshida, Ira Tabas, Kirk J. Wangensteen, Robert F. Schwabe
Publikováno v:
Gastroenterology. 164:1279-1292