Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Robert F Margolskee"'
Autor:
Nanako Atsumi, Keiko Yasumatsu, Yuriko Takashina, Chiaki Ito, Norihisa Yasui, Robert F Margolskee, Atsuko Yamashita
Publikováno v:
eLife, Vol 12 (2023)
Salt taste sensation is multifaceted: NaCl at low or high concentrations is preferably or aversively perceived through distinct pathways. Cl− is thought to participate in taste sensation through an unknown mechanism. Here, we describe Cl− ion bin
Externí odkaz:
https://doaj.org/article/954be8e0867a40d6b47cae87bedcd584
Publikováno v:
PLoS Biology, Vol 21, Iss 1, p e3001647 (2023)
The oral microbiome is second only to its intestinal counterpart in diversity and abundance, but its effects on taste cells remains largely unexplored. Using single-cell RNASeq, we found that mouse taste cells, in particular, sweet and umami receptor
Externí odkaz:
https://doaj.org/article/56b24ee2f40c4e9d96385328b603d379
Autor:
Paul A S Breslin, Akiko Izumi, Anilet Tharp, Tadahiro Ohkuri, Yoshiaki Yokoo, Linda J Flammer, Nancy E Rawson, Robert F Margolskee
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0256989 (2021)
The taste stimulus glucose comprises approximately half of the commercial sugar sweeteners used today, whether in the form of the di-saccharide sucrose (glucose-fructose) or half of high-fructose corn syrup (HFCS). Therefore, oral glucose has been pr
Externí odkaz:
https://doaj.org/article/63bb85e0136e4ad3a4549c53e793c81c
Autor:
Shingo Takai, Yu Watanabe, Keisuke Sanematsu, Ryusuke Yoshida, Robert F Margolskee, Peihua Jiang, Ikiru Atsuta, Kiyoshi Koyano, Yuzo Ninomiya, Noriatsu Shigemura
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225190 (2019)
Expression of insulin and its receptor (IR) in rodent taste cells has been proposed, but exactly which types of taste cells express IR and the function of insulin signaling in taste organ have yet to be determined. In this study, we analyzed expressi
Externí odkaz:
https://doaj.org/article/867b31370ad047b8845f279eb24b0d8f
Autor:
Yumei Qin, Sunil K Sukumaran, Masafumi Jyotaki, Kevin Redding, Peihua Jiang, Robert F Margolskee
Publikováno v:
PLoS Genetics, Vol 14, Iss 2, p e1007058 (2018)
Mouse taste receptor cells survive from 3-24 days, necessitating their regeneration throughout adulthood. In anterior tongue, sonic hedgehog (SHH), released by a subpopulation of basal taste cells, regulates transcription factors Gli2 and Gli3 in ste
Externí odkaz:
https://doaj.org/article/ec877c55d60c40169879db5eb476efef
Autor:
Weiwei Lei, Aurore Ravoninjohary, Xia Li, Robert F Margolskee, Danielle R Reed, Gary K Beauchamp, Peihua Jiang
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139670 (2015)
Cats are obligate carnivores and under most circumstances eat only animal products. Owing to the pseudogenization of one of two subunits of the sweet receptor gene, they are indifferent to sweeteners, presumably having no need to detect plant-based s
Externí odkaz:
https://doaj.org/article/8d9d80f2c80f4592bd60e01327cd0fa1
Autor:
Peihua Jiang, Jesusa Josue-Almqvist, Xuelin Jin, Xia Li, Joseph G Brand, Robert F Margolskee, Danielle R Reed, Gary K Beauchamp
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93043 (2014)
A growing body of behavioral and genetic information indicates that taste perception and food sources are highly coordinated across many animal species. For example, sweet taste perception is thought to serve to detect and motivate consumption of sim
Externí odkaz:
https://doaj.org/article/23b4f87056d14dd296413d70c61b2b6b
Autor:
Martina Donadoni, Rafal Kaminski, Shuren Liao, Suhair Al Janabi, Robert F. Margolskee, Mehmet Hakan Ozdener, Ilker K. Sariyer
Publikováno v:
Journal of NeuroVirology. 29:35-44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cdcdb755de0a66e478a4b798d3de06a
https://doi.org/10.1007/s13365-023-01117-3
https://doi.org/10.1007/s13365-023-01117-3
Autor:
Cailu Lin, Masafumi Jyotaki, John Quinlan, Shan Feng, Minliang Zhou, Peihua Jiang, Ichiro Matsumoto, Liquan Huang, Yuzo Ninomiya, Robert F. Margolskee, Danielle R. Reed, Hong Wang
Publikováno v:
bioRxiv
SummaryT2R bitter receptors, encoded byTas2rgenes, are not only critical for bitter taste signal transduction but also important for defense against bacteria and parasites. However, little is known about whether and howTas2rgene expression are regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e98afe1ef4fdca1e291b675daf2887
https://doi.org/10.1101/2023.02.08.527520
https://doi.org/10.1101/2023.02.08.527520
