Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Robert Everley"'
Autor:
Snahel Patel, Barun Bhhatarai, Philamer Calses, Daniel Erlanson, Robert Everley, Susan Fong, Phil Gerken, Johannes C. Hermann, Tiep Le, Li-kai Liu, Evan McMahon, Richard M. Neve, Tony Phan, Allison Roberts, Mikayla Shanafelt, Sophie Siemsgluess, Jocelyn Staunton, Yan Wang, Weiru Wang, Monika Williams, Kevin R. Webster
Publikováno v:
Cancer Research. 83:1142-1142
KRAS is one of the most frequently mutated genes in cancer and was long considered undruggable until the recent discovery of inhibitors that bind the inactive (GDP-bound) form of KRASG12C. The most clinically advanced of these first-generation molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bddeb8c4c1faf2d4674fccb004f29341
https://doi.org/10.1158/1538-7445.am2023-1142
https://doi.org/10.1158/1538-7445.am2023-1142
Autor:
Johannes C. Hermann, Robert Everley, Laura Marholz, Matthew Berberich, Tzu-Yi Yang, Yu-Hsin Chao, Abduselam K. Awol, Michael Shaghafi, Han Yoon, Rohan Varma, Reed Stein, Karsten Krug, Emily Lachtara, Daniel Erlanson, Chris Varma, Kevin R. Webster
Publikováno v:
Cancer Research. 83:5333-5333
a) Many cancer drivers are considered “undruggable” and without targeted treatments because they lack binding sites for conventional small molecules. Here, we introduce The FRONTIER™ Platform applying machine learning (ML), chemoproteomics and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b39fa0446c32ed2dff57e0a06f895301
https://doi.org/10.1158/1538-7445.am2023-5333
https://doi.org/10.1158/1538-7445.am2023-5333