Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Robert Everley"'
Autor:
Snahel Patel, Barun Bhhatarai, Philamer Calses, Daniel Erlanson, Robert Everley, Susan Fong, Phil Gerken, Johannes C. Hermann, Tiep Le, Li-kai Liu, Evan McMahon, Richard M. Neve, Tony Phan, Allison Roberts, Mikayla Shanafelt, Sophie Siemsgluess, Jocelyn Staunton, Yan Wang, Weiru Wang, Monika Williams, Kevin R. Webster
Publikováno v:
Cancer Research. 83:1142-1142
KRAS is one of the most frequently mutated genes in cancer and was long considered undruggable until the recent discovery of inhibitors that bind the inactive (GDP-bound) form of KRASG12C. The most clinically advanced of these first-generation molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bddeb8c4c1faf2d4674fccb004f29341
https://doi.org/10.1158/1538-7445.am2023-1142
https://doi.org/10.1158/1538-7445.am2023-1142
Autor:
Johannes C. Hermann, Robert Everley, Laura Marholz, Matthew Berberich, Tzu-Yi Yang, Yu-Hsin Chao, Abduselam K. Awol, Michael Shaghafi, Han Yoon, Rohan Varma, Reed Stein, Karsten Krug, Emily Lachtara, Daniel Erlanson, Chris Varma, Kevin R. Webster
Publikováno v:
Cancer Research. 83:5333-5333
a) Many cancer drivers are considered “undruggable” and without targeted treatments because they lack binding sites for conventional small molecules. Here, we introduce The FRONTIER™ Platform applying machine learning (ML), chemoproteomics and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b39fa0446c32ed2dff57e0a06f895301
https://doi.org/10.1158/1538-7445.am2023-5333
https://doi.org/10.1158/1538-7445.am2023-5333
Autor:
TURANOV, Anton A., SHCHEDRINA, Valentina A., EVERLEY, Robert A., LOBANOV, Alexei V., Sun Hee YIM, MARINO, Stefano M., GYGI, Steven P., HATFIELD, Dolph L., GLADYSHEV, Vadim N.
Publikováno v:
Biochemical Journal; 9/15/2014, Vol. 462 Issue 3, p555-565, 18p
Autor:
Paulo, Joao A., Lee, Linda S., Wu, Bechien, Repas, Kathryn, Mortele, Koenraad J., Banks, Peter A., Steen, Hanno, Conwell, Darwin L.
Publikováno v:
Pancreas; Aug2010, Vol. 39 Issue 6, p889-896, 8p
Autor:
Paulo, Joao A., Lee, Linda S., Wu, Bechien, Repas, Kathryn, Banks, Peter A., Conwell, Darwin L., Steen, Hanno
Publikováno v:
Electrophoresis; Jul2010, Vol. 31 Issue 14, p2377-2387, 11p
Publikováno v:
Cancer Research. 77:1222-1222
Small molecule kinase inhibitors targeting a specific oncoprotein driving cancer cells have shown great clinical success in the past (e.g. imatinib against leukemia). However, resistance to targeted therapies quickly arises due to plasticity associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aaea522981cd8bbe3713c038e11a628
https://doi.org/10.1158/1538-7445.am2017-1222
https://doi.org/10.1158/1538-7445.am2017-1222
Autor:
Danske Dandridge
This is the definitive work on Americans taken prisoner during the Revolutionary War. The bulk of the book is devoted to personal accounts, many of them moving, of the conditions endured by U.S. prisoners at the hands of the British, as preserved in
Autor:
Peter Wilson Coldham
In 1654 the Bristol City Council passed an ordinance requiring that a register of servants destined for the colonies be kept, the purpose being to prevent the practice of dumping innocent youths into servitude. The registers, covering the period 1654