Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Robert Eskes"'
Autor:
Grzegorz Kudla, Alexandre Ghazi, Bruno Antonsson, Catherine Berrier, Jean-Claude Martinou, Sylvie Montessuit, Robert Eskes
Publikováno v:
Journal of Biological Chemistry. 275:22713-22718
Bid is a proapoptotic, BH3-domain-only member of the Bcl-2 family. In Fas-induced apoptosis, Bid is activated through cleavage by caspase 8 into a 15.5-kDa C-terminal fragment (t(c)Bid) and a 6.5 kDa N-terminal fragment (t(n)Bid). Following the cleav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9713fb7aa5431c8edb811611fd35116
https://doi.org/10.1074/jbc.m003807200
https://doi.org/10.1074/jbc.m003807200
Autor:
Jean-Claude Martinou, Sandra Lauper, Sylvie Montessuit, Robert Eskes, Bruno Antonsson, Kinsey Maundrell, Anthony Nichols, Astrid Osen-Sand, Solange Desagher
Publikováno v:
The Journal of Cell Biology
Here we report that in staurosporine-induced apoptosis of HeLa cells, Bid, a BH3 domain containing protein, translocates from the cytosol to mitochondria. This event is associated with a change in conformation of Bax which leads to the unmasking of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df492485b23fa787000c225cf297bba1
https://doi.org/10.1083/jcb.144.5.891
https://doi.org/10.1083/jcb.144.5.891
Autor:
Elisabeth André, Solange Desagher, Jean-Claude Martinou, Robert Eskes, Stanislav Fakan, Bruno Antonsson, Isabelle Martinou
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology, vol. 144, no. 5, pp. 883-889
Journal of Cell Biology, vol. 144, no. 5, pp. 883-889
During apoptosis induced by various stimuli, cytochrome c is released from mitochondria into the cytosol where it participates in caspase activation. This process has been proposed to be an irreversible consequence of mitochondrial permeability trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc3594b50fb261728f7d7579131c12c
http://europepmc.org/articles/PMC2148194
http://europepmc.org/articles/PMC2148194
Autor:
Christoph Richter, Gonzalo Mazzei, Sylvie Montessuit, Astrid Osen-Sand, Rémy Sadoul, Jean-Claude Martinou, Bruno Antonsson, Anthony Nichols, Robert Eskes
Publikováno v:
The Journal of Cell Biology
Bcl-2 family members either promote or repress programmed cell death. Bax, a death-promoting member, is a pore-forming, mitochondria-associated protein whose mechanism of action is still unknown. During apoptosis, cytochrome C is released from the mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7afdd8175b733b72f6c3da517b1174f
https://doi.org/10.1083/jcb.143.1.217
https://doi.org/10.1083/jcb.143.1.217
Publikováno v:
Cell. 88(6):865-874
The mobile group II introns aI1 and aI2 of yeast mtDNA encode endonuclease activities that cleave intronless DNA target sites to initiate mobility by target DNA–primed reverse transcription. For aI2, sense-strand cleavage occurs mainly by a partial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0492f16e9573c5e96917303a86729bcd
Autor:
Michael Y. Chao, Philip S. Perlman, Lorna Dickson, Robert Eskes, Lu Liu, Alan M. Lambowitz, Hongwen Ma
The yeast mitochondrial DNA group II introns aI1 and aI2 are retroelements that insert site specifically into intronless alleles by a process called homing. Here, we used patterns of flanking marker coconversion in crosses with wild-type and mutant a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65494e9fff3ec34338b93155b16602ba
https://europepmc.org/articles/PMC102150/
https://europepmc.org/articles/PMC102150/
In many types of apoptosis, the proapoptotic protein Bax undergoes a change in conformation at the level of the mitochondria. This event always precedes the release of mitochondrial cytochrome c, which, in the cytosol, activates caspases through bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40c9bd85de8bba6fc8280e8504268bd
https://europepmc.org/articles/PMC85210/
https://europepmc.org/articles/PMC85210/
Publikováno v:
The Biochemical journal.
Bax is a Bcl-2-family protein with pro-apoptotic activity that can form channels in lipid membranes. The protein has been shown to trigger cytochrome c release from mitochondria both in vitro and in vivo. Recombinant human Bax isolated in the presenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8981d0c248fdc585c48bbdf859811f73
https://pubmed.ncbi.nlm.nih.gov/10620504
https://pubmed.ncbi.nlm.nih.gov/10620504
Autor:
John V. Moran, John C. Kennell, Steven Zimmerly, Ronald A. Butow, Philip S. Perlman, Alan M. Lambowitz, Robert Eskes
Publikováno v:
Molecular and cellular biology. 15(5)
Group II introns aI1 and aI2 of the yeast mitochondrial COXI gene are mobile elements that encode an intron-specific reverse transcriptase (RT) activity. We show here that the introns of Saccharomyces cerevisiae ID41-6/161 insert site specifically in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbf285881b123722bb105e11a42f103
https://pubmed.ncbi.nlm.nih.gov/7537853
https://pubmed.ncbi.nlm.nih.gov/7537853
Publikováno v:
Nature. 366(6451)
INTRON mobility at the RNA level1& ndash;8 by splicing reversal at allelic (homing) and non-allelic locations (transposition) has been reported in vitro9& ndash;12. In the living cell, however, only intron homing by unidirectional gene conversion has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244d3be16112b396a4c551f9678c3959
https://pubmed.ncbi.nlm.nih.gov/8232557
https://pubmed.ncbi.nlm.nih.gov/8232557