Improved molecular laboratory productivity by consolidation of testing on the new random-access analyzer Alinity m

Autor: Leana Maree, Francesca Azzato, Allison Glass, Michael J. Palm, Emily Goldstein, Patrick Braun, Heribert Knechten, Birgit Reinhardt, Martin Obermeier, Maria Krügel, Karin Pfeifer, Danijela Lucic, Alba Vilas, Laura Martínez-García, Natalia Marlowe, Gudrun Naeth, Juan Carlos Galán, Monia Pacenti, Francesco Onelia, Stéphane Chevaliez, Rory Gunson, Jens Dhein, Ajith M. Joseph, Robert Ehret

Publikováno v: Journal of Laboratory Medicine, Vol 44, Iss 6, Pp 319-328 (2020)

Objectives Automated molecular analyzers have accelerated diagnosis, allowing earlier intervention and better patient follow-up. A recently developed completely automated molecular analyzer, Alinity™ m (Abbott), offers consolidated, continuous, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411b2c5fe5181d1b6a3342fce4931e0f
https://doi.org/10.1515/labmed-2020-0102

Clinical evaluation of the automated Abbott RealTime SARS-CoV-2, Alinity m SARS-CoV-2, and Alinity m Resp-4-Plex assays

Autor: Robert Ehret, Stefan Breuer, Martin Obermeier, Jens Dhein, Birgit Reinhardt

Publikováno v: Journal of Virological Methods

Background Detection of SARS-CoV-2 infections relies on the use of sensitive, accurate and high throughput RT-PCR assays. Objectives We assessed the analytical performance of the Abbott RealTime SARS-CoV-2 (RT-SARS), Alinity m SARS-CoV-2 (AlinSARS) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800960e95724e557b6785af40931b8bb
http://europepmc.org/articles/PMC8532389

Multicenter clinical evaluation of alinity m HCV assay performance

Autor: Stéphane Chevaliez, Francesco Onelia, Monia Pacenti, Emily Goldstein, Juan-Carlos Galán, Laura Martínez-García, Alba Vilas, Allison Glass, Leana Maree, Maria Krügel, Robert Ehret, Heribert Knechten, Patrick Braun, Gudrun Naeth, Sara Bonanzinga, Kathy Jackson, Klara Abravaya, Jens Dhein, Shihai Huang, Ajith M. Joseph, Danijela Lucic, Natalia Marlowe, Michael J. Palm, Karin Pfeifer, Dan Toolsie, Birgit Reinhardt, Martin Obermeier, Rory Gunson

Publikováno v: Journal of Clinical Virology
Journal of Clinical Virology, Elsevier, 2020, 129, pp.104531-. ⟨10.1016/j.jcv.2020.104531⟩
Journal of Clinical Virology, 2020, 129, pp.104531-. ⟨10.1016/j.jcv.2020.104531⟩

International audience; Background: Nucleic acid testing is essential for the detection and quantification of HCV RNA in the diagnosis of HCV infection and treatment monitoring. The Alinity m HCV assay was recently developed by Abbott Molecular for r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6df7f9b4a812f7af3d5658254d699d8
https://hal.archives-ouvertes.fr/hal-03491380

Establishment of an anti-hepatitis C virus IgG avidity test for dried serum/plasma spots

Autor: Stefan Ross, Daniel Schmidt, Martin Obermeier, Matthias an der Heiden, Barbara Bartmeyer, Amare Eshetu, Robert Ehret, Karolin Meixenberger, Norbert Bannert, Claus-Thomas Bock, Viviane Bremer, Andrea Hauser

Publikováno v: Journal of immunological methods. 479

Monitoring recency of infection helps to identify current transmission in vulnerable populations for effective disease control. We have established an in-house avidity based hepatitis C virus (HCV) recency assay based on the Monolisa Anti-HCV PLUS Ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ca655f389bb3165186f778a4f9d8ae
https://pubmed.ncbi.nlm.nih.gov/31958450

Comparison of two immunoassays for concurrent detection of HCV antigen and antibodies among HIV/HCV co-infected patients in dried serum/plasma spots

Autor: Amare Eshetu, Norbert Bannert, Andrea Hauser, Daniel Schmidt, Martin Obermeier, Barbara Bartmeyer, Viviane Bremer, Alexander Volkwein, Claus-Thomas Bock, Robert Ehret

Publikováno v: Journal of Virological Methods. 279:113839

Hepatitis C virus (HCV) antigen/antibody (Ag/Ab) assays offer the benefit of reducing the window period compared to assays that detect only HCV-Ab. In this study the performance of the Murex Ag/Ab (Murex, Abbott) and Monolisa Ag/Ab Ultra (Monolisa, B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4387e3866751ee9a7be6a9428b0d72a0
https://doi.org/10.1016/j.jviromet.2020.113839