Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Robert E. Pitas"'
Autor:
Gizem Rizki, Lorenzo Arnaboldi, Bianca Gabrielli, Jim Yan, Gene S. Lee, Ray K. Ng, Scott M. Turner, Thomas M. Badger, Robert E. Pitas, Jacquelyn J. Maher
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 10, Pp 2280-2290 (2006)
Lipogenic diets that are completely devoid of methionine and choline (MCD) induce hepatic steatosis. MCD feeding also provokes systemic weight loss, for unclear reasons. In this study, we found that MCD feeding causes profound hepatic suppression of
Externí odkaz:
https://doaj.org/article/bdbadbe1c52c4642a47078b42fbf70fc
Autor:
Matthias Schneider, Joseph L. Witztum, Stephen G. Young, Erwin H. Ludwig, Elizabeth R. Miller, Sotirios Tsimikas, Linda K. Curtiss, Santica M. Marcovina, John M. Taylor, Richard M. Lawn, Thomas L. Innerarity, Robert E. Pitas
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 4, Pp 769-778 (2005)
Efforts to elucidate the role of lipoprotein [a] (Lp[a]) in atherogenesis have been hampered by the lack of an animal model with high plasma Lp[a] levels. We produced two lines of transgenic mice expressing apolipoprotein [a] (apo[a]) in the liver an
Externí odkaz:
https://doaj.org/article/c7cddf410c7d4802996d9f55cdd11fad
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 11, Pp 1881-1889 (2002)
We present a murine model that examines the effects of macrophage-produced apolipoprotein E3 (apoE3) and apoE4 on VLDL and high density lipoprotein (HDL) metabolism. Mice expressing apoE3 on the Apoe−/− background had substantially lower VLDL lev
Externí odkaz:
https://doaj.org/article/95e56aedea884033ad13810c60474a2d
Autor:
Jacquelyn J. Maher, Lorenzo Arnaboldi, Ray K. Ng, Jim Yan, Gene S. Lee, Robert E. Pitas, Gizem Rizki, Thomas M. Badger, Scott M. Turner, Bianca Gabrielli
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 10, Pp 2280-2290 (2006)
Lipogenic diets that are completely devoid of methionine and choline (MCD) induce hepatic steatosis. MCD feeding also provokes systemic weight loss, for unclear reasons. In this study, we found that MCD feeding causes profound hepatic suppression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee8e38bedefedd9abc19cf21e4a9e5b
https://doi.org/10.1194/jlr.m600198-jlr200
https://doi.org/10.1194/jlr.m600198-jlr200
Autor:
Lennart Mucke, Robert E. Pitas
Publikováno v:
Neuron. 43:596-599
Interactions between environmental and genetic factors may contribute to neurodegenerative disease. In this issue of Neuron, Calon et al. report that a diet low in an essential omega-3 polyunsaturated fatty acid (docosahexaenoic acid) depletes postsy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce89528b3348154993cda1437eb683b
https://doi.org/10.1016/j.neuron.2004.08.025
https://doi.org/10.1016/j.neuron.2004.08.025
Autor:
Hubert C. Chen, Steven J. Smith, Zuleika Ladha, Dalan R. Jensen, Luis D. Ferreira, Leslie K. Pulawa, James G. McGuire, Robert E. Pitas, Robert H. Eckel, Robert V. Farese
Publikováno v:
Journal of Clinical Investigation. 109:1049-1055
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abdf841c1ef998ae3413c8d0a3899fcd
https://doi.org/10.1172/jci0214672
https://doi.org/10.1172/jci0214672
Publikováno v:
Journal of Biological Chemistry. 276:30655-30661
Upon activation, platelets secrete a 120-kDa protein that competes for the binding and internalization of acetyl low density lipoproteins (AcLDL) by macrophages. From the amino-terminal amino acid sequence, amino acid composition, and immunoblot anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c0415da65f88b8c8704dd7d4fc6c84
https://doi.org/10.1074/jbc.m102879200
https://doi.org/10.1074/jbc.m102879200
Publikováno v:
Journal of Biological Chemistry. 275:17661-17670
Oxidative stress caused by phorbol esters or reactive oxygen up-regulates the class A scavenger receptor (SR-A) in human smooth muscle cells (SMC), which normally do not express this receptor. The increase in SR-A expression correlates with activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4847091153057739cf7eaafcab92b0fc
https://doi.org/10.1074/jbc.275.23.17661
https://doi.org/10.1074/jbc.275.23.17661
Autor:
Manuel Buttini, Lennart Mucke, Tony Wyss-Coray, Robert E. Pitas, Robert W. Mahley, Carol Lin, Hassibullah Akeefe
Publikováno v:
Neuroscience. 97:207-210
Apolipoprotein E fulfills fundamental functions in lipid transport and neural tissue repair after injury.(6,8) Its three most common isoforms (E2, E3, and E4) are critical determinants of diverse human diseases, including major cardiovascular and neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ae46d1025dbd6780523826604cd832
https://doi.org/10.1016/s0306-4522(00)00069-5
https://doi.org/10.1016/s0306-4522(00)00069-5
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 18:1440-1449
Abstract —Reactive oxygen species generated by treatment of smooth muscle cells (SMCs) with either phorbol 12-myristate 13-acetate or with the combination of H 2 O 2 and vanadate strongly induce expression of the class A scavenger receptor (SR-A) g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb34f3557c7ba0d341db0daab83e34a
https://doi.org/10.1161/01.atv.18.9.1440
https://doi.org/10.1161/01.atv.18.9.1440