Výsledky vyhledávání - "Robert E. Palermo"

Akademický článek

Next-Generation Sequencing of Small RNAs from HIV-Infected Cells Identifies Phased microRNA Expression Patterns and Candidate Novel microRNAs Differentially Expressed upon Infection

Autor: Stewart T. Chang, Matthew J. Thomas, Pavel Sova, Richard R. Green, Robert E. Palermo, Michael G. Katze

Publikováno v: mBio, Vol 4, Iss 1 (2013)

ABSTRACT HIV infection of CD4+ T cells induces a range of host transcriptional changes in mRNAs as well as microRNAs that may coordinate changes in mRNAs. To survey these dynamic changes, we applied next-generation sequencing, analyzing the small RNA

Externí odkaz: https://doaj.org/article/34dcfe49b7474662bc2f271122daeb5d

Zobrazit plný text záznamu

Akademický článek

Next-Generation Sequencing Reveals HIV-1-Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4+ T Cell Line

Autor: Stewart T. Chang, Pavel Sova, Xinxia Peng, Jeffrey Weiss, G. Lynn Law, Robert E. Palermo, Michael G. Katze

Publikováno v: mBio, Vol 2, Iss 5 (2011)

ABSTRACT Next-generation sequencing (NGS) enables the highly sensitive measurement of whole transcriptomes. We report the first application to our knowledge of this technology to the analysis of RNA from a CD4+ T cell line infected with intact HIV. W

Externí odkaz: https://doaj.org/article/4335629fcdcd4a7c9458980a08e6dea5

Zobrazit plný text záznamu

Akademický článek

Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine.

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e19681 (2011)

While HIV-1-specific cellular immunity is thought to be critical for the suppression of viral replication, the correlates of protection have not yet been determined. Rhesus macaques (RM) are an important animal model for the study and development of

Externí odkaz: https://doaj.org/article/832e20b4e604483faf325caae46dd2dc

Zobrazit plný text záznamu

Akademický článek

Copy number variation of CCL3-like genes affects rate of progression to simian-AIDS in Rhesus Macaques (Macaca mulatta).

Autor: Jeremiah D Degenhardt, Paola de Candia, Adrien Chabot, Stuart Schwartz, Les Henderson, Binhua Ling, Meredith Hunter, Zhaoshi Jiang, Robert E Palermo, Michael Katze, Evan E Eichler, Mario Ventura, Jeffrey Rogers, Preston Marx, Yoav Gilad, Carlos D Bustamante

Publikováno v: PLoS Genetics, Vol 5, Iss 1, p e1000346 (2009)

Variation in genes underlying host immunity can lead to marked differences in susceptibility to HIV infection among humans. Despite heavy reliance on non-human primates as models for HIV/AIDS, little is known about which host factors are shared and w

Externí odkaz: https://doaj.org/article/aef92161213745ddaa6043f88e71a440

Zobrazit plný text záznamu

Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 3, p e1008377 (2020)

The recombinant Canarypox ALVAC-HIV/gp120/alum vaccine regimen was the first to significantly decrease the risk of HIV acquisition in humans, with equal effectiveness in both males and females. Similarly, an equivalent SIV-based ALVAC vaccine regimen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828c037a81c823bb9d41fecb2386bbc0
https://doi.org/10.1371/journal.ppat.1008377

Zobrazit plný text záznamu

Assessment and improvement of Indian-origin rhesus macaque and Mauritian-origin cynomolgus macaque genome annotations using deep transcriptome sequencing data

Autor: Christopher E. Mason, Hao Xiong, Gary P. Schroth, Daniel C. Jones, Walter L. Ruzzo, Xinxia Peng, Lenore Pipes, Michael G. Katze, Richard Green, Robert E. Palermo

Publikováno v: Journal of Medical Primatology

Background The genome annotations of rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques, two of the most common non-human primate animal models, are limited. Methods We analyzed large-scale macaque RNA-based next-generation sequenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07c46d3ebf8d18c1b3e43fd870b28b1
https://doi.org/10.1111/jmp.12125

Zobrazit plný text záznamu

Plný text ve formátu HTML

Enabling large-scale next-generation sequence assembly with Blacklight

Autor: Christopher E. Mason, Lenore Pipes, M. Brian Couger, Fabio M. Squina, Philip D. Blood, Adam Siepel, Rolf A. Prade, Robert E. Palermo, Michael G. Katze

Publikováno v: Concurrency and Computation: Practice and Experience. 26:2157-2166

A variety of extremely challenging biological sequence analyses were conducted on the XSEDE large shared memory resource Blacklight, using current bioinformatics tools and encompassing a wide range of scientific applications. These include genomic se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cea73257f506abb89fbffe53e33c6804
https://doi.org/10.1002/cpe.3231

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání