Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Robert E. Monticone"'
Autor:
Mingyi Wang, Kimberly Raginski McGraw, Robert E. Monticone, Roberta Giordo, Ali H. Eid, Gianfranco Pintus
Publikováno v:
Aging Medicine, Vol 7, Iss 3, Pp 414-423 (2024)
Abstract Arterial stiffening is a critical risk factor contributing to the exponential rise in age‐associated cardiovascular disease incidence. This process involves age‐induced arterial proinflammation, collagen deposition, and calcification, wh
Externí odkaz:
https://doaj.org/article/ba6539ec90134f9c8beaec113fb3989d
Autor:
Leng Ni, Lijuan Liu, Wanqu Zhu, Richard Telljohann, Jing Zhang, Robert E. Monticone, Kimberly R. McGraw, Changwei Liu, Christopher H. Morrell, Pablo Garrido‐Gil, Jose Luis Labandeira‐Garcia, Edward G. Lakatta, Mingyi Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 17 (2022)
Background Age‐associated aortic remodeling includes a marked increase in intimal medial thickness (IMT), associated with signs of inflammation. Although aortic wall milk fat globule–epidermal growth factor VIII (MFG‐E8) increases with age, and
Externí odkaz:
https://doaj.org/article/bf073e5d078f47adae6b593d9d3cd4ae
Publikováno v:
Aging Medicine, Vol 3, Iss 3, Pp 159-168 (2020)
Abstract Aging is a major risk factor for quintessential cardiovascular diseases, which are closely related to arterial proinflammation. The age‐related alterations of the amount, distribution, and properties of the collagen fibers, such as cross
Externí odkaz:
https://doaj.org/article/c0fbcad9c70d441aae32015bd48b8ad6
Publikováno v:
Cells, Vol 12, Iss 2, p 253 (2023)
Medin, a small 50-amino acid peptide, is an internal cleaved product from the second discoidin domain of milk fat globule epidermal growth factor VIII (MFG-E8) protein. Medin has been reported as the most common amylogenic protein in the upper part o
Externí odkaz:
https://doaj.org/article/50be853c9bda43e0acebd26d7d139926
Autor:
Mingyi Wang, Li Zhang, Wanqu Zhu, Jing Zhang, Soo Hyuk Kim, Yushi Wang, Leng Ni, Richard Telljohann, Robert E. Monticone, Kimberly McGraw, Lijuan Liu, Rafael de Cabo, Edward G. Lakatta
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 18 (2018)
Background Aging exponentially increases the incidence of morbidity and mortality of quintessential cardiovascular disease mainly due to arterial proinflammatory shifts at the molecular, cellular, and tissue levels within the arterial wall. Calorie r
Externí odkaz:
https://doaj.org/article/1cb3608c3ec6469ea847c976e5e863a8
Autor:
Keva Li, Cristina Florio, Christopher Morrell, Robert E Monticone, Bruce Ziman, Edward G Lakatta
Publikováno v:
Circulation Research. 131
Cardiovascular diseases and aging induce stress on the heart, resulting in heart wall thickness and stiffness associated with increased fibrosis. The sinoatrial node (SAN) is the heart’s natural pacemaker composed of a fibrous tissue matrix with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2849d4e29fd8cff415671fc9cc49ad5
https://doi.org/10.1161/res.131.suppl_1.p2034
https://doi.org/10.1161/res.131.suppl_1.p2034
Autor:
Leng Ni, Lijuan Liu, Wanqu Zhu, Richard Telljohann, Jing Zhang, Robert E. Monticone, Kimberly R. McGraw, Changwei Liu, Christopher H. Morrell, Pablo Garrido-Gil, Jose Luis Labandeira-Garcia, Edward G. Lakatta, Mingyi Wang
BackgroundAngiotensin II (Ang II) and milk fat globule-epidermal growth factor VIII (MFG-E8) are involved in age-associated arterial remodeling; however, the inflammatory role of MFG-E8 in Ang II associated arterial remodeling with aging remains unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54c7fa71fb107400e24a1e1b78e4f433
https://doi.org/10.1101/2021.03.11.434767
https://doi.org/10.1101/2021.03.11.434767
Publikováno v:
Mech Ageing Dev
Elastic fibers are the main components of the extracellular matrix of the large arterial wall. Elastic fiber remodeling is an intricate process of synthesis and degradation of the core elastin protein and microfibrils accompanied by the assembly and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e4c10ff9ecb01662c09dc3a776e85d
https://pubmed.ncbi.nlm.nih.gov/33839189
https://pubmed.ncbi.nlm.nih.gov/33839189
Publikováno v:
Aging Medicine
Aging Medicine, Vol 3, Iss 3, Pp 159-168 (2020)
Aging Medicine, Vol 3, Iss 3, Pp 159-168 (2020)
Aging is a major risk factor for quintessential cardiovascular diseases, which are closely related to arterial proinflammation. The age‐related alterations of the amount, distribution, and properties of the collagen fibers, such as cross‐links an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec8345038142bfd81ae4229fe9755da
https://pubmed.ncbi.nlm.nih.gov/33103036
https://pubmed.ncbi.nlm.nih.gov/33103036
Autor:
Jing Zhang, Robert E. Monticone, Soo Hyuk Kim, Roberta Giordo, Kimberly R. McGraw, Leng Ni, Richard Telljohann, Lijuan Liu, Wanqu Zhu, Gianfranco Pintus, Yushi Wang, Li Zhang, Chloe Ferris, Edward G. Lakatta, Mingyi Wang
Publikováno v:
Oncotarget. 9:27117-27132
The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. Angiotensin II (Ang II) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b50db39abf3af878938de697208f63
https://doi.org/10.18632/oncotarget.25499
https://doi.org/10.18632/oncotarget.25499