Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Robert E. Lanford"'
Autor:
Christopher Y. Chen, Benjamin Y. Winer, Deborah Chavez, Bernadette Guerra, Kathleen M. Brasky, Stacey Eng, Eduardo Salas, Danny Tam, Joe H. Simmons, Christian R. Abee, William E. Delaney, Alexander Ploss, Robert E. Lanford, Christian Voitenleitner
Publikováno v:
Hepatology Communications, Vol 4, Iss 3, Pp 371-386 (2020)
Development of curative therapies for chronic hepatitis B virus (HBV) infection will likely require new animal models. Here, we evaluate HBV infection in squirrel monkeys based on the high‐sequence homology of the HBV receptor, Na+/taurocholate co
Externí odkaz:
https://doaj.org/article/911c91724d604a958917fa3c7de7fa65
Autor:
Zhifang Qiu, Anuja Mishra, Miao Li, Steven L. Farnsworth, Bernadette Guerra, Robert E. Lanford, Peter J. Hornsby
Publikováno v:
Stem Cell Research, Vol 15, Iss 1, Pp 141-150 (2015)
The marmoset is an important nonhuman primate model for regenerative medicine. For experimental autologous cell therapy based on induced pluripotent (iPS) cells in the marmoset, cells must be able to undergo robust and reliable directed differentiati
Externí odkaz:
https://doaj.org/article/498f280578934c1b8606dec03a86e7d1
Autor:
Jonathan K. Mitchell, Bentley R. Midkiff, Benjamin Israelow, Matthew J. Evans, Robert E. Lanford, Christopher M. Walker, Stanley M. Lemon, David R. McGivern
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Many DNA tumor viruses promote cellular transformation by inactivating the critically important tumor suppressor protein p53. In contrast, it is not known whether p53 function is disrupted by hepatitis C virus (HCV), a unique, oncogenic RNA
Externí odkaz:
https://doaj.org/article/9c7aab5b79d24bc7ab1c2afe955f3b68
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 2, Pp 275-286 (1999)
Plasma levels of atherogenic lipoprotein [a] (Lp[a]) vary over a 1000-fold range and are largely determined by the gene for its unique glycoprotein, apolipoprotein [a] (apo[a]). The apo[a] locus comprises more than 100 alleles, encoding proteins from
Externí odkaz:
https://doaj.org/article/372df0c1d9ec4febbd425d16d2f9a9a8
Autor:
Benjamin Y. Winer, Kathleen M. Brasky, Robert E. Lanford, Christian R. Abee, William E. Delaney, Alexander Ploss, Deborah Chavez, Joe H. Simmons, Danny Tam, Christopher Y. Chen, Christian Voitenleitner, Eduardo Salas, Bernadette Guerra, Stacey Eng
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 4, Iss 3, Pp 371-386 (2020)
Hepatology Communications, Vol 4, Iss 3, Pp 371-386 (2020)
Development of curative therapies for chronic hepatitis B virus (HBV) infection will likely require new animal models. Here, we evaluate HBV infection in squirrel monkeys based on the high-sequence homology of the HBV receptor, Na+/taurocholate co-tr
Autor:
Luis B. Barreiro, Robert E. Lanford, Jean-Christophe Grenier, Mohamed B. F. Hawash, Jessica F. Brinkworth, Jordan N. Kohn, Joaquin Sanz-Remón, Vania Yotova, Zach Johnson
Publikováno v:
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Despite their close genetic relatedness, apes and African and Asian monkeys (AAMs) differ in their susceptibility to severe bacterial and viral infections that are important causes of human disease. Such differences between humans and other primates
Autor:
Ariadna Grinyo, Elias H. Augestad, Mayda Hernandez, Netanel Tzarum, Kenna Nagy, Robyn L. Stanfield, Linling He, Mansun Law, Robert E. Lanford, Rodrigo Velázquez-Moctezuma, Deborah Chavez, Xiaohe Lin, Jens Bukh, Erick Giang, Ian A. Wilson, Mallorie E. Fouch, Jannick Prentoe, Benjamin J. Doranz, Jiang Zhu, Fang Chen
Publikováno v:
Immunity
Chen, F, Tzarum, N, Lin, X, Giang, E, Velázquez-Moctezuma, R, Augestad, E H, Nagy, K, He, L, Hernandez, M, Fouch, M E, Grinyó, A, Chavez, D, Doranz, B J, Prentoe, J, Stanfield, R L, Lanford, R, Bukh, J, Wilson, I A, Zhu, J & Law, M 2021, ' Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins ', Immunity, vol. 54, no. 4, pp. 781-796.e4 . https://doi.org/10.1016/j.immuni.2021.02.013
Chen, F, Tzarum, N, Lin, X, Giang, E, Velázquez-Moctezuma, R, Augestad, E H, Nagy, K, He, L, Hernandez, M, Fouch, M E, Grinyó, A, Chavez, D, Doranz, B J, Prentoe, J, Stanfield, R L, Lanford, R, Bukh, J, Wilson, I A, Zhu, J & Law, M 2021, ' Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins ', Immunity, vol. 54, no. 4, pp. 781-796.e4 . https://doi.org/10.1016/j.immuni.2021.02.013
Human IGHV1-69-encoded broadly neutralizing antibodies (bnAbs) that target the hepatitis C virus (HCV) envelope glycoprotein (Env) E2 are important for protection against HCV infection. An IGHV1-69 ortholog gene, VH1.36, is preferentially used for bn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9b240bcbc75d463054a656be6471f1
https://europepmc.org/articles/PMC8046733/
https://europepmc.org/articles/PMC8046733/
Autor:
Elizabeth Clemmons, Sharon Price, Deborah Chavez, Robert E. Lanford, Laura Condel, John Dutton
Publikováno v:
J Vet Pharmacol Ther
Incidence of Bordetella pertussis, the causative agent of whooping cough, is rising in some global human populations despite high vaccination rates, and significant research is underway to address the issue. Baboons are an established model for pertu
Autor:
Robert E. Lanford, Jean-Christophe Grenier, Luis B. Barreiro, Joaquin Sanz-Remón, Jordan N. Kohn, Jessica F. Brinkworth, Mohamed B. F. Hawash, Vania Yotova, Zach Johnson
Despite their close genetic relatedness, apes and African and Asian monkeys (AAMs), strongly differ in their susceptibility to severe bacterial and viral infections that are important causes of human disease. Such differences between humans and other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cba1671db233525198b6d82a8e23288c
https://doi.org/10.1101/2020.07.23.218339
https://doi.org/10.1101/2020.07.23.218339
Autor:
Dorothy French, Congrong Niu, Robert E. Lanford, Vivian Barry, Stephane Daffis, Igor Mikaelian, William E. Delaney, Erik Huntzicker, Simon P. Fletcher, Li Li
Publikováno v:
Journal of Hepatology. 68:912-921
Background & Aims GS-9620, an oral agonist of toll-like receptor 7, is in clinical development for the treatment of chronic hepatitis B (CHB). GS-9620 was previously shown to induce prolonged suppression of serum viral DNA and antigens in the chimpan