Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Robert E. Boswell"'
Publikováno v:
Developmental Biology. 308(2):507-519
A protein complex consisting of Mago Nashi and Tsunagi/Y14 is required to establish the major body axes and for the localization of primordial germ cell determinants during Drosophila melanogaster oogenesis. The Mago Nashi:Tsunagi/Y14 heterodimer als
Autor:
Fredrick D Oakley, Yukiko Yamada, Clark R. Coffman, Rachel C Strohm, Danielle Przychodzin, Robert E. Boswell
Publikováno v:
Genetics. 162:273-284
Drosophila germ cells form at the posterior pole of the embryo and migrate to the somatic gonad. Approximately 50% of the germ cells that form reach their target. The errant cells within the embryo undergo developmentally regulated cell death. Prior
Autor:
Stephanie E. Mohr, Robert E. Boswell
Publikováno v:
Genetics. 160:1503-1510
A genetic screen to identify mutations in genes in the 45A region on the right arm of chromosome 2 that are involved in oogenesis in Drosophila was undertaken. Several lethal but no female sterile mutations in the region had previously been identifie
Publikováno v:
Developmental Biology. 218(2):172-182
The Caenorhabditis elegans gene mag-1 can substitute functionally for its homolog mago nashi in Drosophila and is predicted to encode a protein that exhibits 80% identity and 88% similarity to Mago nashi (P. A. Newmark et al., 1997, Development 120,
Zimp encodes a homologue of mouse Miz1 and PIAS3 and is an essential gene in Drosophila melanogaster
Autor:
Stephanie E. Mohr, Robert E. Boswell
Publikováno v:
Gene. 229:109-116
The related mouse proteins Miz1 and PIAS3, which have predicted zinc finger domains, interact with the transcription factors Msx2 and STAT3, modulating the ability of Msx2 and STAT3 to regulate transcription. Here, we describe a Drosophila gene, zimp
Autor:
Joseph B. Duffy, Christian Ghiglione, Robert E. Boswell, Laufey T. Amundadottir, Norbert Perrimon, Kermit L. Carraway
Publikováno v:
Cell. 96(6):847-856
We have identified the Drosophila transmembrane molecule kekkon 1 (kek1) as an inhibitor of the epidermal growth factor receptor (EGFR) and demonstrate that it acts in a negative feedback loop to modulate the activity of the EGFR tyrosine kinase. Dur
Publikováno v:
Europe PubMed Central
Establishment of the anteroposterior and dorsoventral axes in the Drosophila egg chamber requires reciprocal signaling between the germ line and soma. Upon activation of the Drosophila EGF receptor in the posterior follicle cells, these cells signal
Autor:
Phillip A. Newmark, Robert E. Boswell
Publikováno v:
Development (Cambridge, England). 120(5)
In Drosophila, the localization of maternal determinants to the posterior pole of the oocyte is required for abdominal segmentation and germ cell formation. These processes are disrupted by maternal effect mutations in ten genes that constitute the p
Publikováno v:
Development (Cambridge, England). 119(1)
Mutations in the tudor locus of Drosophila affect two distinct determinative processes in embryogenesis; segmentation of the abdomen and determination of the primordial germ cells. The distribution of tudor protein during embryogenesis, and the effec
Publikováno v:
Genesdevelopment. 5(11)
The tudor (tud) locus of Drosophila melanogaster is required during oogenesis for the formation of primordial germ cells and for normal abdominal segmentation. The tud locus was cloned, and its product was identified by Northern analysis of wild-type