Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robert E. Bagdon"'
Publikováno v:
Journal of Controlled Release. 44:43-53
Intravaginal devices (diaphragm and disc) were fabricated from silicone elastomer and evaluated for controlled release of Nonoxynol-9 (N-9). These intravaginal devices have good physical properties and reproducibility. A significant amount of N-9 was
Publikováno v:
Journal of Toxicology and Environmental Health. 40:613-641
Although hexavalent chromium, Cr(VI), is a potent sensitizer and inducer of allergic contact dermatitis and is found in many common materials, no standard or guideline currently exists for protection against these effects in environmental exposure. T
Autor:
Robert E. Bagdon, Robert E. Hazen
Publikováno v:
Environmental Health Perspectives
A literature review of experimental and human exposure studies of skin permeation and cutaneous hypersensitivity reactions evoked by chromium was carried out to provide a basis for making a risk assessment of chromium as a soil contaminant. In vitro
Publikováno v:
Pharmaceutical Research. :1000-1010
Several transdermal contraceptive device (TCD) formulations were developed to provide a dual-controlled transdermal delivery of levonorgestrel (LN), a potent progestin, and 17 beta-estradiol (E2), a natural estrogen. Using a sensitive HPLC method, th
Autor:
Robert J. Van Ryzin, Robert E. Bagdon, Raymond E. Stoll, Rodney L. Robison, Richard D. Jensen
Publikováno v:
Fundamental and Applied Toxicology. 4:394-405
The benzodiazepine temazepam was given to Charles River CD rats for 2 years in the diet at dosages of 10, 40, and 160 mg/kg day. An 18-month study was performed in Charles River CD-1 mice via dietary admixture at dosages of 10, 80, and 160 mg/kg/day.
Publikováno v:
Angiology. 13:4-12
Autor:
Robert E. Bagdon, Gerhard Zbinden
Publikováno v:
Toxicology and Applied Pharmacology. 6:214-219
Toxicity measurements of the schistosomicide TWSb indicate this trivalent antimonial to be well tolerated by rats given daily intramuscular injections of 100 mg/kg, 10 mg/kg, and 1 mg/kg for 15 weeks; these doses are equivalent to daily administratio
Publikováno v:
Clinical Pharmacology & Therapeutics. 5:273-276
Publikováno v:
Toxicology and Applied Pharmacology. 3:619-637
The effects of excessive doses of chlordiazepoxide in animals and in 22 patients who had attempted suicide are described. In most subjects, single doses up to 2250 mg caused sedation, often ataxia and dysarthria, and in rare instances sleep and coma.
Publikováno v:
Toxicology and applied pharmacology. 1(1)
Sulfadimethoxine (2,4-dimethoxy-6-sulfanilamido-1,3-diazine) is a new sulfonamide having low toxicity after single oral administration to rats and dogs. Chronic toxicity studies of sulfadimethoxine [Madribon (Ro-4-0517)] were conducted in rats at dos