Výsledky vyhledávání - "Robert E. Atchison"

Sequence, Structure, and Chromosomal Mapping of the MouseLgals6 Gene, Encoding Galectin-6

Autor: Robert E. Atchison, Samuel H. Barondes, Aldons J. Lusis, Michael A. Gitt, Hakon Leffler, Yu-Rong Xia

Publikováno v: Journal of Biological Chemistry. 273:2961-2970

In the accompanying paper (Gitt, M. A., Colnot, C., Poirier, F., and Barondes, S. H., and Leffler, H. (1998) J. Biol. Chem. 273, 2954-2960), we reported that mouse gastrointestinal tract specifically expresses two closely related galectins, galectins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0bdf53bd08c318004e6afaa4582fa7
https://doi.org/10.1074/jbc.273.5.2961

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Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop

Autor: Roberto F. Speck, Robert E. Atchison, Kathy Wehrly, Bruce Chesebro, Israel F. Charo, Mark A. Goldsmith, Emily J. Platt, David Kabat

Publikováno v: Journal of Virology. 71:7136-7139

The chemokine receptor CCR5 acts as an essential cofactor for cell entry by macrophage-tropic human immunodeficiency virus type 1 (HIV-1) strains, whereas CXCR4 acts as an essential cofactor for T-cell-line-adapted strains. We demonstrated that the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85782c80a09cc70091b246596990e6a5
https://doi.org/10.1128/jvi.71.9.7136-7139.1997

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Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity

Autor: Hidenori Arai, Jennifa Gosling, Israel F. Charo, Mark A. Goldsmith, Robert E. Atchison, Felipe S. Monteclaro, Chia-Lin Tsou

Publikováno v: Proceedings of the National Academy of Sciences. 94:5061-5066

The C-C chemokine receptor 5 (CCR5) plays a crucial role in facilitating the entry of macrophage-tropic strains of the HIV-1 into cells, but the mechanism of this phenomenon is completely unknown. To explore the role of CCR5-derived signal transducti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf9f8fb7b7bc273edfdfaa278a2b9a5
https://doi.org/10.1073/pnas.94.10.5061

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Multiple roles for the receptor tyrosine kinase axl in tumor formation

Publikováno v: Cancer research. 65(20)

A focus of contemporary cancer therapeutic development is the targeting of both the transformed cell and the supporting cellular microenvironment. Cell migration is a fundamental cellular behavior required for the complex interplay between multiple c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3373a1184125d13ee43e22fe1f12359f
https://pubmed.ncbi.nlm.nih.gov/16230391

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Susceptibility of Rat-Derived Cells to Replication by Human Immunodeficiency Virus Type 1

Autor: David L. Hirschberg, Tuan A. Ngo, Wesley Yonemoto, Mark A. Goldsmith, Kathryn S. Patton, Demetris C. Iacovides, Robert E. Atchison, Oliver T. Keppler, Frank J. Welte, Roberto F. Speck

Progress in developing a small animal model of human immunodeficiency virus type 1 (HIV-1) disease would greatly facilitate studies of transmission, pathogenesis, host immune responses, and antiviral strategies. In this study, we have explored the po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080e9b67a8d8bee252da7254a955665c
https://europepmc.org/articles/PMC115050/

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Molecular function of the CD4 D1 domain in coreceptor-mediated entry by HIV type 1

Autor: Mark A. Goldsmith, Raymond W. Sweet, Robert E. Atchison, Roberto F. Speck, Ursula Esser, Keith Charles Deen

Publikováno v: AIDS research and human retroviruses. 16(17)

The surface molecule CD4 plays a key role in initiating cellular entry by the human immunodeficiency virus type 1 (HIV-1), and it is now recognized as acting synergistically with select chemokine receptors (coreceptors) in the infection process. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cab7e3809e862c04069cbdbb5f7ccdf
https://pubmed.ncbi.nlm.nih.gov/11118070

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Rabbit cells expressing human CD4 and human CCR5 are highly permissive for human immunodeficiency virus type 1 infection

Autor: Ursula Esser, Thomas J. Kindt, Mark A. Goldsmith, Bishop F. Hague, Robert E. Atchison, Wimmer J, Michael L. Penn, Roberto F. Speck

Publikováno v: Journal of virology. 72(7)

To evaluate the feasibility of using transgenic rabbits expressing CCR5 and CD4 as a small-animal model of human immunodeficiency virus type 1 (HIV) disease, we examined whether the expression of the human chemokine receptor (CCR5) and human CD4 woul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6750b6b335e829faee4cb10b115acde3
https://pubmed.ncbi.nlm.nih.gov/9621031

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Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines

Autor: Laura Digilio, Israel F. Charo, Mark A. Goldsmith, Robert E. Atchison, Jennifa Gosling, Christian Franci, Felipe S. Monteclaro

Publikováno v: Science (New York, N.Y.). 274(5294)

The human beta-chemokine receptor CCR5 is an important cofactor for entry of human immunodeficiency virus-type 1 (HIV-1). The murine form of CCR5, despite its 82 percent identity to the human form, was not functional as an HIV-1 coreceptor. HIV-1 ent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4649e2318217000cee4a105f1118d6b9
https://pubmed.ncbi.nlm.nih.gov/8943208

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