Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Robert E T, Tainsh"'
Autor:
Emmanuel S Buys, Yu-Chieh Ko, Clemens Alt, Sarah R Hayton, Alexander Jones, Laurel T Tainsh, Ruiyi Ren, Andrea Giani, Maeva Clerté, Emma Abernathy, Robert E T Tainsh, Dong-Jin Oh, Rajeev Malhotra, Pankaj Arora, Nadine de Waard, Binglan Yu, Raphael Turcotte, Daniel Nathan, Marielle Scherrer-Crosbie, Stephanie J Loomis, Jae H Kang, Charles P Lin, Haiyan Gong, Douglas J Rhee, Peter Brouckaert, Janey L Wiggs, Meredith S Gregory, Louis R Pasquale, Kenneth D Bloch, Bruce R Ksander
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60156 (2013)
Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we report that mice lacking the α1 subunit of the nitric oxide receptor soluble guanyla
Externí odkaz:
https://doaj.org/article/cdb4e77ca1f6419cb61140dd1cfbf975
Autor:
Emmanuel S, Buys, Michael J, Raher, Andrew, Kirby, Mohd, Shahid, Shahid, Mohd, David M, Baron, Sarah R, Hayton, Laurel T, Tainsh, Patrick Y, Sips, Kristen M, Rauwerdink, Qingshang, Yan, Robert E T, Tainsh, Hannah R, Shakartzi, Christine, Stevens, Kelly, Decaluwé, Maria da Gloria, Rodrigues-Machado, Rajeev, Malhotra, Johan, Van de Voorde, Tong, Wang, Peter, Brouckaert, Mark J, Daly, Kenneth D, Bloch
Publikováno v:
JOURNAL OF CLINICAL INVESTIGATION
Nitric oxide (NO) plays an essential role in regulating hypertension and blood flow by inducing relaxation of vascular smooth muscle. Male mice deficient in a NO receptor component, the α1 subunit of soluble guanylate cyclase (sGCα1), are prone to