Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Robert E Hurst"'
Autor:
Nataliya Smith, Debra Saunders, Megan Lerner, Michelle Zalles, Nadezda Mamedova, Daniel Cheong, Ehsan Mohammadi, Tian Yuan, Yi Luo, Robert E Hurst, Beverley Greenwood-Van Meerveld, Rheal A Towner
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239282 (2020)
ObjectivesTo determine if the URO-MCP-1 mouse model for bladder IC/BPS is associated with in vivo bladder hyper-permeability, as measured by contrast-enhanced MRI (CE-MRI), and assess whether molecular-targeted MRI (mt-MRI) can visualize in vivo clau
Externí odkaz:
https://doaj.org/article/4d581eccc4644cf9805cc4080521a6cd
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129466 (2015)
PurposeThe differentiated superficial cells of the urothelium restrict urine flow into the bladder wall. We have demonstrated that urothelial cells isolated from bladders of patients with interstitial cystitis/painful bladder syndrome (IC/PBS) fail t
Externí odkaz:
https://doaj.org/article/af59c41784924562ad6d229b72a58130
Autor:
Lora C Bailey-Downs, Jessica E Thorpe, Bryan C Disch, Anja Bastian, Paul J Hauser, Taleah Farasyn, William L Berry, Robert E Hurst, Michael A Ihnat
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98624 (2014)
Most cancer patients die with metastatic disease, thus, good models that recapitulate the natural process of metastasis including a dormancy period with micrometastatic cells would be beneficial in developing treatment strategies. Herein we report a
Externí odkaz:
https://doaj.org/article/967fbcee865c4483aaa8b78b6ac2df83
Autor:
John O Marentette, Paul J Hauser, Robert E Hurst, David J Klumpp, Alice Rickard, Jane McHowat
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69948 (2013)
The pathogenesis of interstitial cystitis/painful bladder syndrome (IC/PBS) is multifactorial, but likely involves urothelial cell dysfunction and mast cell accumulation in the bladder wall. Activated mast cells in the bladder wall release several in
Externí odkaz:
https://doaj.org/article/f45afc680a594ef2aa7e01968542d298
Autor:
Robert E Hurst, Paul J Hauser, Kimberly D Kyker, Jonathan E Heinlen, Jason P Hodde, Michael C Hiles, Stanley D Kosanke, Mikhail Dozmorov, Michael A Ihnat
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64181 (2013)
A major problem in cancer research is the lack of a tractable model for delayed metastasis. Herein we show that cancer cells suppressed by SISgel, a gel-forming normal ECM material derived from Small Intestine Submucosa (SIS), in flank xenografts sho
Externí odkaz:
https://doaj.org/article/c41542a398374ce6a6bca80616173b65
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
The number of methods for pre-processing and analysis of gene expression data continues to increase, often making it difficult to select the most appropriate approach. We present a simple procedure for comparative estimation of a variety of methods f
Externí odkaz:
https://doaj.org/article/cecf0bc6ee184dd186b2c58e7984e3e6
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2298 (2021)
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic, often incapacitating condition characterized by pain seeming to originate in the bladder in conjunction with lower urinary tract symptoms of frequency and urgency, and consists of a w
Externí odkaz:
https://doaj.org/article/bdbe45bf5ba141a38ec5f3ff397fcf10
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Cancer recurrence remains a great fear for many cancer survivors following their initial, apparently successful, therapy. Despite significant improvement in the overall survival of many types of cancer, metastasis accounts for ~90% of all cancer mort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca901e764d84104653d28df6aadfade
http://europepmc.org/articles/PMC8111294
http://europepmc.org/articles/PMC8111294
Autor:
Debra Saunders, Harrison C. Shain, Nataliya Smith, Beverley Greenwood-Van Meerveld, Ehsan Mohammadi, Robert E. Hurst, Thomas H. Jozefiak, Grannum R. Sant, Rheal A. Towner
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 1, Pp n/a-n/a (2021)
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives
Few therapeutic options exist for treatment of IC/BPS. A novel high MW GAG biopolymer (“SuperGAG”) was synthesized by controlled oligomerization of CS, purified by TFF and characterized by SEC‐MALLS and 1H‐NMR spectroscopy. The modified GAG b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3315bef807e923f3eb796be8f950ae13
https://doi.org/10.1002/prp2.709
https://doi.org/10.1002/prp2.709
Autor:
Debra Saunders, Rheal A. Towner, Bradley P. Kropp, Sundararajan V. Madihally, Christopher E. Aston, Ding Xia, Qing Yang, Robert E. Hurst, Beverley Greenwood-Van Meerveld, Nataliya Smith, Kar Ming Fung, Hsueh Kung Lin
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 106:1778-1787
Augmentation enterocystoplasty remains the gold standard surgical bladder reconstruction procedure to increase the capacity and compliance of dysfunctional bladders. Since the use of the patient's intestine has severe risks of complications, alternat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1afc3ee8139b592c0a4578564daa102a
https://doi.org/10.1002/jbm.b.33985
https://doi.org/10.1002/jbm.b.33985