Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Robert E Bruccoleri"'
Autor:
Rui-Ru Ji, Heshani de Silva, Yisheng Jin, Robert E Bruccoleri, Jian Cao, Aiqing He, Wenjun Huang, Paul S Kayne, Isaac M Neuhaus, Karl-Heinz Ott, Becky Penhallow, Mark I Cockett, Michael G Neubauer, Nathan O Siemers, Petra Ross-Macdonald
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 9, p e1000512 (2009)
The dose response curve is the gold standard for measuring the effect of a drug treatment, but is rarely used in genomic scale transcriptional profiling due to perceived obstacles of cost and analysis. One barrier to examining transcriptional dose re
Externí odkaz:
https://doaj.org/article/2200014703f348538cb5cd6ad646b99a
Autor:
Robert E. Bruccoleri, Edward J. Oakeley, Ann Marie E. Faust, Marc Altorfer, Sophie Dessus-Babus, David Burckhardt, Mevion Oertli, Ulrike Naumann, Frank Petersen, Joanne Wong
Publikováno v:
GigaByte (2023)
Irises are perennial plants, representing a large genus with hundreds of species. While cultivated extensively for their ornamental value, commercial interest in irises lies in the secondary metabolites present in their rhizomes. The Dalmatian Iris (
Externí odkaz:
https://doaj.org/article/c68bc30b7c3148eb8f21765f0f38316e
Publikováno v:
International Journal of Peptide and Protein Research. 38:229-236
The leucine zipper motif is a characteristic amino acid sequence found in dimeric DNA-binding proteins. Computer-generated models for leucine zippers were constructed as alpha-helical coiled dimers with leucine repeated every seventh residue. An empi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8197e55a7767d033f292336c94296d55
https://doi.org/10.1111/j.1399-3011.1991.tb01433.x
https://doi.org/10.1111/j.1399-3011.1991.tb01433.x
Autor:
Hyun Uk Kim, Kai Blin, Wolfgang Wohlleben, Daniel Krug, Marnix H. Medema, Srikanth Duddela, Robert E. Bruccoleri, Michael A. Fischbach, Rolf Müller, Rainer Breitling, Tilmann Weber, Sang Yup Lee, Eriko Takano
Publikováno v:
Nucleic acids research, 43(W1), W237-W243
Nucleic Acids Research (London)
Nucleic Acids Research
Weber, T, Blin, K, Duddela, S, Krug, D, Kim, H U, Bruccoleri, R, Lee, S Y, Fischbach, M A, Müller, R & Wohlleben, W 2015, ' antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters ', Nucleic Acids Research, vol. 43, no. W1, pp. W237-W243 . https://doi.org/10.1093/nar/gkv437
Nucleic acids research 43 (2015) W1
Nucleic Acids Research (London)
Nucleic Acids Research
Weber, T, Blin, K, Duddela, S, Krug, D, Kim, H U, Bruccoleri, R, Lee, S Y, Fischbach, M A, Müller, R & Wohlleben, W 2015, ' antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters ', Nucleic Acids Research, vol. 43, no. W1, pp. W237-W243 . https://doi.org/10.1093/nar/gkv437
Nucleic acids research 43 (2015) W1
Microbial secondary metabolism constitutes a rich source of antibiotics, chemotherapeutics, insecti- cides and other high-value chemicals. Genome min- ing of gene clusters that encode the biosynthetic pathways for these metabolites has become a key m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a010c29de48b6bf7becf82a0c32bac0d
https://hdl.handle.net/10033/555475
https://hdl.handle.net/10033/555475
Publikováno v:
Bioinformatics
Summary: Dose–response information is critical to understanding drug effects, yet analytical methods for dose–response assays cannot cope with the dimensionality of large-scale screening data such as the microarray profiling data. To overcome thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56c56b59884fa0b6aff2c72383fd086
http://europepmc.org/articles/PMC3187656
http://europepmc.org/articles/PMC3187656
Publikováno v:
Immunology today. 8(1)
Much recent progress has been made in understanding the nature of antigenicity in the generation of antibodies. In this article Jiři Novotný and his colleagues discuss properties such as accessibility, flexibility and shape which determine the anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f0ff25249a25c7c7c71401063c769f
https://pubmed.ncbi.nlm.nih.gov/25291494
https://pubmed.ncbi.nlm.nih.gov/25291494
Publikováno v:
Journal of Molecular Modeling. 7:164-168
Empirical free energy calculations were performed for the engrailed homeodomain mutant protein in complex with its consensus promoter. The program, CONGEN™, was used to generate the atomic coordinates, which were missing in the original crystal str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a6f3093951d4bc5154ba64157a5ad88
https://doi.org/10.1007/s008940100018
https://doi.org/10.1007/s008940100018
Publikováno v:
Nucleic Acids Research. 26:4482-4486
The set of proteins which are conserved across families of microbes contain important targets of new anti-microbial agents. We have developed a simple and efficient computational tool which determines concordances of putative gene products that show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4d17d3f56e17ec10bec67e1d1dacdd
https://doi.org/10.1093/nar/26.19.4482
https://doi.org/10.1093/nar/26.19.4482
Publikováno v:
Journal of Computational Chemistry. 18:268-276
A common problem in the calculation of electrostatic potentials with the Poisson-Boltzmann equation using finite difference methods is the effect of molecular position relative to the grid. Previously a uniform charging method was shown to reduce the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5f5c05b01e5d8de2341dd5983fb6e97
https://doi.org/10.1002/(sici)1096-987x(19970130)18:2<268::aid-jcc11>3.0.co
https://doi.org/10.1002/(sici)1096-987x(19970130)18:2<268::aid-jcc11>3.0.co
Autor:
Robert E. Bruccoleri
Publikováno v:
ACM SIGPLAN Notices. 31:20-27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb859a8b68fa090d5d683c88b2a6b6b
https://doi.org/10.1145/249118.249122
https://doi.org/10.1145/249118.249122