Zobrazeno 1 - 10 of 393 pro vyhledávání: '"Robert E Brown"'
1
Akademický článek
Quorum-sensing dysbiotic shifts in the HIV-infected oral metabiome.
Autor: Robert E Brown, Mahmoud A Ghannoum, Pranab K Mukherjee, Patrick M Gillevet, Masoumeh Sikaroodi
Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0123880 (2015)
We implemented a Systems Biology approach using Correlation Difference Probability Network (CDPN) analysis to provide insights into the statistically significant functional differences between HIV-infected patients and uninfected individuals. The ana
Externí odkaz: https://doaj.org/article/b02cc16e05794f8888ee0ecb3d899e37
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2
Akademický článek
Oral mycobiome analysis of HIV-infected patients: identification of Pichia as an antagonist of opportunistic fungi.
Autor: Pranab K Mukherjee, Jyotsna Chandra, Mauricio Retuerto, Masoumeh Sikaroodi, Robert E Brown, Richard Jurevic, Robert A Salata, Michael M Lederman, Patrick M Gillevet, Mahmoud A Ghannoum
Publikováno v: PLoS Pathogens, Vol 10, Iss 3, p e1003996 (2014)
Oral microbiota contribute to health and disease, and their disruption may influence the course of oral diseases. Here, we used pyrosequencing to characterize the oral bacteriome and mycobiome of 12 HIV-infected patients and matched 12 uninfected con
Externí odkaz: https://doaj.org/article/f7d6d9306ece40f9b7c1124be690ffba
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3
Akademický článek
Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumors.
Autor: Yunyun Jiang, Vivek Subbiah, Filip Janku, Joseph A Ludwig, Aung Naing, Robert S Benjamin, Robert E Brown, Pete Anderson, Razelle Kurzrock
Publikováno v: PLoS ONE, Vol 9, Iss 8, p e93676 (2014)
Ewing's sarcoma (ES) and desmoplastic small round cell tumors (DSRCT) are small round blue cell tumors driven by an N-terminal containing EWS translocation. Very few somatic mutations have been reported in ES, and none have been identified in DSRCT.
Externí odkaz: https://doaj.org/article/e0c11bbc3ba74cb08c40d17a3a1d26a0
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4
Akademický článek
Morphoproteomic profiling of the mammalian target of rapamycin (mTOR) signaling pathway in desmoplastic small round cell tumor (EWS/WT1), Ewing's sarcoma (EWS/FLI1) and Wilms' tumor(WT1).
Autor: Vivek Subbiah, Robert E Brown, Yunyun Jiang, Jamie Buryanek, Andrea Hayes-Jordan, Razelle Kurzrock, Pete M Anderson
Publikováno v: PLoS ONE, Vol 8, Iss 7, p e68985 (2013)
Desmoplastic small round cell tumor (DSRCT) is a rare sarcoma in adolescents and young adults. The hallmark of this disease is a EWS-WT1 translocation resulting from apposition of the Ewing's sarcoma (EWS) gene with the Wilms' tumor (WT1) gene. We pe
Externí odkaz: https://doaj.org/article/b90e90f09f3742f0a0b227a532f38ec6
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5
Akademický článek
Targeted morphoproteomic profiling of Ewing's sarcoma treated with insulin-like growth factor 1 receptor (IGF1R) inhibitors: response/resistance signatures.
Autor: Vivek Subbiah, Aung Naing, Robert E Brown, Helen Chen, Laurence Doyle, Patricia LoRusso, Robert Benjamin, Pete Anderson, Razelle Kurzrock
Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18424 (2011)
Insulin-like growth factor 1 receptor (IGF1R) targeted therapies have resulted in responses in a small number of patients with advanced metastatic Ewing's sarcoma. We performed morphoproteomic profiling to better understand response/resistance mechan
Externí odkaz: https://doaj.org/article/c1774ebb81754da9ae9d338d6b931a79
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