Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Robert E Blouch"'
Autor:
Ling Jin, Kathleen Eide, Robert E. Blouch, Robert J. Bildfell, Patrick L. Iversen, David A. Stein, Megan Moerdyk-Schauwecker
Publikováno v:
Antiviral Research. 84:131-141
Alternative therapies are needed for HSV-1 infections in patients refractory to treatment with Acyclovir (ACV) and its derivatives. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) are single-stranded DNA analogues that enter cells r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1e1dd4445b14b89a74c800cc3ba13d
https://doi.org/10.1016/j.antiviral.2009.07.020
https://doi.org/10.1016/j.antiviral.2009.07.020
Autor:
Robert E. Blouch, Viktoriya Borisevich, David A. Stein, Yinghong Ma, Slobodan Paessler, Rene Rijnbrand, Natallia Dziuba, Patrick L. Iversen, Alexey Seregin, Haolin Ni, Michele A. Zacks, Nadezhda E. Yun
Publikováno v:
Virology
The genus Alphavirus contains members that threaten human health, both as natural pathogens and as potential biological weapons. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) enter cells readily and can inhibit viral replication t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f1ce2dbb16f36fa65913cf25e9dabe
Autor:
Stacy Crumley, Claire Y.-H. Huang, Shawn J. Silengo, Patrick L. Iversen, Robert E. Blouch, Adams Amantana, David A. Stein, Richard M. Kinney
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives: To determine the antiviral activity of phosphorodiamidate morpholino oligomers (PMO) and peptide-conjugated PMO (PPMO) in AG129 mice infected with dengue 2 virus (DENV-2). Methods: Antisense PMO and PPMO were designed against the 5 0 term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50d25e12821b0f21e6281bf3bc1d610
http://europepmc.org/articles/PMC7109848
http://europepmc.org/articles/PMC7109848
Autor:
Decheng Yang, Shaun R. Coughlin, Yinjing Wang, Zhen Liu, David A. Stein, Robert E. Blouch, Ji Yuan, Hong M. Moulton, Travis Lim, Dexin Qiu, Patrick L. Iversen
Publikováno v:
Journal of Virology. 80:11510-11519
Coxsackievirus B3 (CVB3) is a primary cause of viral myocarditis, yet no effective therapeutic against CVB3 is available. Nucleic acid-based interventional strategies against various viruses, including CVB3, have shown promise experimentally, but lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991bf9d859bcb68099e7e4cefc621e6a
https://doi.org/10.1128/jvi.00900-06
https://doi.org/10.1128/jvi.00900-06
Publikováno v:
Virology Journal
Virology Journal, Vol 2, Iss 1, p 91 (2005)
Virology Journal, Vol 2, Iss 1, p 91 (2005)
L1R, a myristylated late gene product of vaccinia virus, is essential for formation of infectious intracellular mature virions (IMV). In its absence, only viral particles arrested at an immature stage are detected and no infectious progeny virus is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24e16cb74a9e3ff9f7cc90136ff824b
https://pubmed.ncbi.nlm.nih.gov/16336686
https://pubmed.ncbi.nlm.nih.gov/16336686
Autor:
Donald K. Nichols, M. Javad Aman, Robert E. Blouch, Kelly L. Warfield, Gene G. Olinger, Patrick L. Iversen, William D. Pratt, David A. Stein, Dana L. Swenson, Sina Bavari
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 2, Iss 1, p e1 (2006)
PLoS Pathogens, Vol 2, Iss 1, p e1 (2006)
The filoviruses Marburg virus and Ebola virus (EBOV) quickly outpace host immune responses and cause hemorrhagic fever, resulting in case fatality rates as high as 90% in humans and nearly 100% in nonhuman primates. The development of an effective th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce2e17c8d7a7a740a45314f64ce55cb
https://doi.org/10.1371/journal.ppat.0020001
https://doi.org/10.1371/journal.ppat.0020001
Autor:
Sina Bavari, Gordon Ruthel, Robert E. Blouch, Jed N. Hassinger, Travis K. Warren, Hong M. Moulton, Dwight D. Weller, Patrick L. Iversen, Kelly L. Warfield, Candace E. Lovejoy, Dana L. Swenson
Publikováno v:
BASE-Bielefeld Academic Search Engine
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy
Phosphorodiamidate morpholino oligomers (PMOs) are uncharged nucleic acid-like molecules designed to inactivate the expression of specific genes via the antisense-based steric hindrance of mRNA translation. PMOs have been successful at knocking out v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea79edee0040ff78d744936c39e51879
Autor:
David A. Stein, Claire Y.-H. Huang, Shawn Silengo, Adams Amantana, Stacy Crumley, Robert E. Blouch, Patrick L. Iversen, Richard M. Kinney, Stein, David A, Huang, Claire Y-H, Silengo, Shawn, Amantana, Adams, Crumley, Stacy, Blouch, Robert E, Iversen, Patrick L, Kinney, Richard M
Publikováno v:
Journal of Antimicrobial Chemotherapy (JAC); Sep2008, Vol. 62 Issue 3, p555-555, 1p