Zobrazeno 1 - 10
of 333
pro vyhledávání: '"Robert E, McCullumsmith"'
Autor:
Smita Sahay, Emily A. Devine, Christina F.-A. Vargas, Robert E. McCullumsmith, Sinead M. O’Donovan
Publikováno v:
Cells, Vol 13, Iss 19, p 1657 (2024)
Schizophrenia is a neuropsychiatric illness characterized by altered neurotransmission, in which adenosine, a modulator of glutamate and dopamine, plays a critical role that is relatively unexplored in the human brain. In the present study, postmorte
Externí odkaz:
https://doaj.org/article/833e0b4929eb46729b2bc3565f62e9f2
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/e7ef308044734979bf28b79cd19b847c
Autor:
Jennifer Nguyen, Melissa A. Curtis, Ali S. Imami, William G. Ryan, Khaled Alganem, Kari L. Neifer, Nilanjana Saferin, Charlotte N. Nawor, Brian P. Kistler, Gary W. Miller, Rammohan Shukla, Robert E. McCullumsmith
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/19421693822744e0944eb21064314f3a
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/7d84655ac0d342299f5b7e02f5f95dda
Autor:
Zahra Kolahchi, Nicholas Henkel, Mahmoud A. Eladawi, Emma C. Villarreal, Prathik Kandimalla, Anna Lundh, Robert E. McCullumsmith, Elvis Cuevas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8485 (2024)
Two-thirds of Americans with Alzheimer’s disease are women, indicating a profound variance between the sexes. Variances exist between the sexes in the age and intensity of the presentation, cognitive deficits, neuroinflammatory factors, structural
Externí odkaz:
https://doaj.org/article/6d9ce41528ad4425807c39755f7262c0
Autor:
Smita Sahay, Priyanka Pulvender, Madhu Vishnu Sankar Reddy Rami Reddy, Robert E. McCullumsmith, Sinead M. O’Donovan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8266 (2024)
The disruption of brain energy metabolism, leading to alterations in synaptic signaling, neural circuitry, and neuroplasticity, has been implicated in severe mental illnesses such as schizophrenia, bipolar disorder, and major depressive disorder. The
Externí odkaz:
https://doaj.org/article/3abb94532a054e5a980f16f8626ea399
Publikováno v:
Brain Sciences, Vol 14, Iss 7, p 649 (2024)
Gene expression alterations in postmortem schizophrenia tissue are well-documented and are influenced by genetic, medication, and epigenetic factors. The Wingless/Integrated (WNT) signaling pathway, critical for cell growth and development, is involv
Externí odkaz:
https://doaj.org/article/6a2c5fce52374b8f9f7e0a03cb86996c
Autor:
Justin H. Franco, Ryan A. Harris, William G. Ryan, Roger Travis Taylor, Robert E. McCullumsmith, Saurabh Chattopadhyay, Zhixing K. Pan
Publikováno v:
Viruses, Vol 16, Iss 1, p 140 (2024)
The ongoing COVID-19 pandemic has revealed the shortfalls in our understanding of how to treat coronavirus infections. With almost 7 million case fatalities of COVID-19 globally, the catalog of FDA-approved antiviral therapeutics is limited compared
Externí odkaz:
https://doaj.org/article/89be7e9094b6477595294fa78a97a567
Publikováno v:
Cells, Vol 13, Iss 1, p 32 (2023)
Schizophrenia is a devastating neuropsychiatric disorder associated with the dysregulation of glutamate and dopamine neurotransmitter systems. The adenosine system is an important neuroregulatory system in the brain that modulates glutamate and dopam
Externí odkaz:
https://doaj.org/article/ae1650806d634066a95d9383bec7ac6a
Autor:
Ketan K. Marballi, Khaled Alganem, Samuel J. Brunwasser, Arhem Barkatullah, Kimberly T. Meyers, Janet M. Campbell, Annika B. Ozols, Robert E. Mccullumsmith, Amelia L. Gallitano
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Bioinformatics and network studies have identified the immediate early gene transcription factor early growth response 3 (EGR3) as a master regulator of genes differentially expressed in the brains of patients with neuropsychiatric illnesses
Externí odkaz:
https://doaj.org/article/81fb50e775ac47e18e756a66b4665804