Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Robert Delsite"'
Autor:
Noriko Mori, Robert Delsite, Kshama Natarajan, Mariola Kulawiec, Zaver M. Bhujwalla, Keshav K. Singh
Publikováno v:
Molecular Imaging, Vol 3 (2004)
Mutations in the p53 gene are the most frequently observed genetic lesions in human cancers. Human cancers that contain a p53 mutation are more aggressive, more apt to metastasize, and more often fatal. p53 controls numerous downstream targets that c
Externí odkaz:
https://doaj.org/article/871514f9ed05415493d93ce7befbe797
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Results for each of the 16 identified hits in the panel of IR foci formation assays, and additional clonogenic survival data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2413ea7aafb134ab76274203272711
https://doi.org/10.1158/1535-7163.22503628
https://doi.org/10.1158/1535-7163.22503628
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
HR and mNHEJ results of the high-throughput screen presented as a 2D RADaR plot.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affcfc049296b668007e6b53f1e5e578
https://doi.org/10.1158/1535-7163.22503646.v1
https://doi.org/10.1158/1535-7163.22503646.v1
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Additional data for hits from the primary screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862ddc972d914ec15877873254bb58fd
https://doi.org/10.1158/1535-7163.22503625
https://doi.org/10.1158/1535-7163.22503625
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Additional cell-based DSB repair assay optimization studies in preparation for high-throughput screening.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f6558e3af8443e735e7eadca176f48
https://doi.org/10.1158/1535-7163.22503649
https://doi.org/10.1158/1535-7163.22503649
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Counter-screen to rule out small molecule hits which may non-specifically inhibit fluorescence leading to false positive results.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363a45bd2ba127a23d0d20bd8664920e
https://doi.org/10.1158/1535-7163.22503640.v1
https://doi.org/10.1158/1535-7163.22503640.v1
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Results for each of the 16 identified hits in the GFP-based DSB repair assay panel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225d3f5c3b7be29d618d0f5357d3cc5a
https://doi.org/10.1158/1535-7163.22503631
https://doi.org/10.1158/1535-7163.22503631
Autor:
Ranjit S. Bindra, Simon N. Powell, J. Fraser Glickman, Harriet M. Kluger, Maria Jasin, Jennifer A. Wilshire, Petrus J. Hendrikx, Jeanne Chiaravalli, Ranjini K. Sundaram, Ahmed F. Salem, David Shahbazian, Antonio N. Luz, Robert Delsite, Alexander G. Goglia
Validation of the GFP-based DSB repair assay panel using known DSB repair inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1ebe2f06538b79892c3abcaa88396d
https://doi.org/10.1158/1535-7163.22503637.v1
https://doi.org/10.1158/1535-7163.22503637.v1
Autor:
Marc Ladanyi, Matthew J. Bott, Valerie W. Rusch, Simon N. Powell, Marie Brevet, Ronglai Shen, Barry S. Taylor, Boris Reva, Maureen F. Zakowski, Qin Zhou, Jenette Creaney, Robert Delsite, Lu Wang, Richard A. Lake, Shigeki Shimizu, Adam B. Olshen, Tatsuo Ito, Chris Sander
Publikováno v:
Nature Genetics. 43:668-672
Malignant pleural mesotheliomas (MPMs) often show CDKN2A and NF2 inactivation, but other highly recurrent mutations have not been described. To identify additional driver genes, we used an integrated genomic analysis of 53 MPM tumor samples to guide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9017fec86b560b5c1e137cf10cfe5c7e
https://doi.org/10.1038/ng.855
https://doi.org/10.1038/ng.855
Autor:
Christine A. Iacobuzio-Donahue, Caitlin Jones, Gokce Askan, Pedro Blecua Carrillo Albornoz, Peter J. Allen, Nadeem Riaz, Jacklynn V. Egger, Cristian D. Cruz, Rui Wang, Robert Delsite, Tanisha Leach, Nicolas Lecomte, Liguo Zhang, Eileen M. O'Reilly, Nicholas D. Socci, Marc F Attiyeh, Brian Herbst, Vicky Baudin, Jerry P. Melchor, Mohammed A. Al Efishat, Steven D. Leach, Kenneth H. Yu
Publikováno v:
Annals of Pancreatic Cancer. 1:AB098-AB098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b131ff82354fb22534fe28a8192529
https://doi.org/10.21037/apc.2018.ab098
https://doi.org/10.21037/apc.2018.ab098