Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert Dalton Chavez"'
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217709 (2019)
ObjectiveIntravascular stents are commonly used to treat occluded arteries during coronary heart disease. After coronary stent implantation, endothelial cells grow over the stent, which is referred to as re-endothelialization. Re-endothelialization p
Externí odkaz:
https://doaj.org/article/f24af3ec9da2477abc8bff5cb16cd7c6
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210601 (2019)
ObjectivePrg4, also known as Lubricin, acts as a joint/boundary lubricant. Prg4 has been used to prevent surgically induced osteoarthritis (OA) in mice. Surgically induced OA serves as a good model for post-traumatic OA but is not ideal for recapitul
Externí odkaz:
https://doaj.org/article/42e8c9a292a94c49a4c483551c16da1a
ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages
Autor:
Emilie Barruet, Edward C. Hsiao, Ashley Pereira, Amy N. Ton, Robert Dalton Chavez, Judith Hellman, Koji Matsuo, Aditi Sharma, Abigail Lepinski, Mary C. Nakamura, Tania Moody, Kiichiro Tomoda
Publikováno v:
Bone
Macrophages play crucial roles in many human disease processes. However, obtaining large numbers of primary cells for study is often difficult. We describe 2D and 3D methods for directing human induced pluripotent stem cells (hiPSCs) into macrophages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a459adf8af853d372f3236392ca08011
https://escholarship.org/uc/item/9bn0c1hc
https://escholarship.org/uc/item/9bn0c1hc
Publikováno v:
Osteoarthritis and Cartilage. 25:332-340
Summary Objective We previously identified 3′-phosphoadenosine 5′-phosphosulfate synthase 2 ( PAPSS2 ) as a transcriptional target of transforming growth factor β (TGF-β) in chondrocytes. PAPSS2 is required for proper sulfation of proteoglycans
Publikováno v:
Curr Osteoporos Rep
PURPOSE OF REVIEW: Heterotopic ossification (HO) is associated with inflammation. The goal of this review is to examine recent findings on the roles of inflammation and the immune system in HO. We examine how inflammation triggers HO in fibrodysplasi
Autor:
Robert Dalton Chavez, Rosa Serra
Publikováno v:
Biotechnology Progress. 36
Reduced transforming growth factor beta (TGF-β) signaling is associated with osteoarthritis (OA). TGF-β is thought to act as a chondroprotective agent and provide anabolic cues to cartilage, thus acting as an OA suppressor in young, healthy cartila