Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Robert D. Wurster"'
Publikováno v:
Neuroscience Bulletin
Excessive reactive oxygen species (ROS) (such as the superoxide radical) are commonly associated with cardiac autonomic dysfunctions. Though superoxide dismutase 1 (SOD1) overexpression may protect against ROS damage to the autonomic nervous system,
Autor:
Jin Chen, Jeffery T. Hatcher, Robert D. Wurster, Zhaozhong Li, Li Chen, Qing-Hui Chen, Zixi Cheng, Sic L. Chan
Publikováno v:
Frontiers in Neuroscience
Transient receptor potential canonical 6 (TRPC6) channels are permeable to Na+ and Ca2+ and are widely expressed in the brain. In this study, the role of TRPC6 was investigated following ischemia/reperfusion (I/R) and oxygen-glucose deprivation (OGD)
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 300:R1070-R1078
Previously, we demonstrated that maternal diabetes reduced the excitability and increased small-conductance Ca2+-activated K+(SK) currents of parasympathetic cardiac motoneurons (PCMNs) in the nucleus ambiguus (NA). In addition, blockade of SK channe
Autor:
Zixi Jack Cheng, Chenghui Huang, Lihua Li, Min Lin, Scott W Harden, Robert D. Wurster, Jing Ai
Publikováno v:
Autonomic Neuroscience. 155:39-48
Baroreflex control of heart rate (HR) is impaired in human diabetes mellitus and in large experimental models. However, baroreflex impairment in diabetic mouse models and diabetes-induced remodeling of baroreflex circuitry are not well studied. We ex
Publikováno v:
Autonomic Neuroscience. 152:67-74
Baroreflex control of heart rate (HR) is impaired in human type 1 diabetes mellitus. The goal of this study is to use a transgenic mouse model of type 1 diabetes (OVE26) to assess the diabetes-induced baroreflex impairment in the conscious state. OVE
Publikováno v:
The Journal of Spinal Cord Medicine. 33:135-143
To test the feasibility of implanting intramuscular electrodes (Permaloc, Synapse Biomedical Inc, Oberlin OH) with self-securing polypropylene anchors to stimulate upper-intercostal and abdominal muscles plus the diaphragm.In 6 anesthetized dogs, 12
Publikováno v:
Neuroscience. 161:78-85
To investigate the effects of chronic diabetes on baroreflex control of renal sympathetic nerve activity (RSNA), OVE26 diabetic (transgenic mouse line which develops hyperglycemia within the first 3 weeks after birth) and FVB control mice 5-6 months
Publikováno v:
Autonomic Neuroscience. 145:93-98
Nitric oxide and carbon monoxide are diffusible gas messengers, synthesized by nitric oxide synthase or heme oxygenase 2, respectively, that can activate soluble guanylyl cyclase in adjacent cells. Nitric oxide and carbon monoxide neuromodulation in
Autor:
Lisa M. Coughlin, Kathryn J. Jones, Sam J. Marzo, Ryan G. Porter, Nijee Sharma, Lisa Tanzer, Robert D. Wurster, Eileen M. Foecking
Publikováno v:
Restorative Neurology and Neuroscience. 27:635-646
Purpose The neurotherapeutic effects of nerve electrical stimulation and gonadal steroids have independently been demonstrated. The purpose of this study was to investigate the therapeutic potential of a combinatorial treatment strategy of electrical
Autor:
Robert D. Wurster, James S. Walter, Andrew Jahoda, Thomas M.T. Turk, John S. Wheeler, Larissa Bresler
Publikováno v:
The Journal of Rehabilitation Research and Development. 45:627-638
Urinary retention is a serious urological problem associated with spinal cord injuries (SCIs) and other pelvic disorders. Effective methods of pelvic nerve stimulation were investigated for this problem. Following anesthesia in five dogs, the bladder