Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robert D. Shurina"'
Autor:
Lisa Misner, Thomas G. O'Brien, James M. Mullin, Robert D. Shurina, Shotaro Imaizumi, Jasna Noe, Kathleen V. Snock, Kenneth D. George
Publikováno v:
Journal of Cellular Physiology. 152:35-47
In previous experiments we have shown that acute (30 minutes) exposure to phorbol esters or other protein kinase C activators causes increased transepithelial permeability, specifically by the increased paracellular permeability through tight junctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec5c7a5f4bdfd75f9e047a15c8bd955
https://doi.org/10.1002/jcp.1041520106
https://doi.org/10.1002/jcp.1041520106
Publikováno v:
Chemical Research in Toxicology. 3:333-339
Hydroquinone, a metabolite that accumulates in bone marrow following benzene exposure, was oxidized by prostaglandin H synthase (PHS) to 1,4-benzoquinone, which was measured by HPLC with reductive electrochemistry. Hydroquinone metabolism in the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ba998f5fc5bacb04b4442968c82ec1
https://doi.org/10.1021/tx00016a010
https://doi.org/10.1021/tx00016a010
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468458794
Chronic exposure of humans to benzene causes bone marrow depression leading to pancytopenia and aplastic anemia (Goldstein, B.D., 1983). Benzene also causes genotoxic effects such as structural chromosome aberrations and DNA strand breaks (Dean, B.J.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f322222903557e9b1e3e5684f8d34cc
https://doi.org/10.1007/978-1-4684-5877-0_60
https://doi.org/10.1007/978-1-4684-5877-0_60
Publikováno v:
Environmental Health Perspectives
Macrophages, an important cell-type of the bone marrow stroma, are possible targets of benzene toxicity because they contain relatively large amounts of prostaglandin H synthase (PHS), which is capable of metabolizing phenolic compounds to reactive s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df6393138b8f0314eb96bc30d1be9bd
https://doi.org/10.1289/ehp.8982229
https://doi.org/10.1289/ehp.8982229
Autor:
Mullin, James M., Snock, Kathleen V., Shurina, Robert D., Noe, Jasna, George, Kenneth, Misner, Lisa, Imaizumi, Shotaro, O'Brien, Thomas G.
Publikováno v:
Journal of Cellular Physiology; Jul1992, Vol. 152 Issue 1, p35-47, 13p