Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Robert D. Rubens"'
Autor:
Chris Twelves, C Cruickshanka, Michael Richards, NA Dobbs, Walter M Gregory, Robert D. Rubens
Publikováno v:
European Journal of Cancer. 39:580-586
This study aimed to develop an epirubicin dose modification scheme in women with breast cancer and liver dysfunction. We first identified target areas under the concentration-time curve (AUCs) of 2400 and 1600 ng/ml.h from pharmacokinetic studies in
Publikováno v:
European Journal of Cancer. 36:476-482
A retrospective analysis of 859 patients who developed bone metastases from breast cancer between 1975 and 1991 was performed in order to identify factors that predict for complications from skeletal disease. The patients were divided into four group
Publikováno v:
British Journal of Cancer
18-Fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) has previously been used successfully to image primary and metastatic breast cancer. In this pilot study, 19 breast cancer patients with symptoms/signs referrable to the brachial plexu
Autor:
Robert D. Rubens, Ignac Fogelman
Bone Metastases brings together the many recent developments that are gradually improving the prospects for patients with secondary involvement of the skeleton in a primary cancer elsewhere. The morbidity from bone metastases is extensive, and the pa
Publikováno v:
British Journal of Cancer
This study aimed to assess the proportion of patients with advanced breast cancer who report benefit from first-line palliative chemotherapy using a simple global measure of wellbeing and to identify factors predicting benefit. A consecutive series o
Publikováno v:
European Journal of Cancer. 34:820-824
47 patients with progressive, painful, predominantly lytic bone metastases from breast cancer were included in a randomised double-blind phase II trial comparing the effects of pamidronate 150 and 300 mg daily. Oral pamidronate produced either sclero
Autor:
Robert D. Rubens
Publikováno v:
European Journal of Cancer. 34:210-213
Publikováno v:
British Journal of Cancer
Three hundred and sixty-seven women presenting to the Breast Unit at Guy's Hospital between 1975 and 1990 whose first distant metastasis was in the skeleton were identified and the influence of a number of patient and tumour characteristics on the de
Publikováno v:
International Journal of Cancer. 74:605-608
We have investigated the relationship between immunohistochemically determined p53 status and outcome in 277 women with node-positive primary breast cancer who, following tumour excision and axillary clearance, were randomised to receive either 6 cyc
Publikováno v:
European Journal of Surgical Oncology (EJSO). 23:348-353
This study aims to define the risk factors for loco-regional relapse following mastectomy, and to assess the efficacy of radiotherapy at the time of relapse. To achieve this 272 patients with loco-regional relapse treated at a single institution with