Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Robert D. Robl"'
Autor:
Andrea R. Daamen, Hongyang Wang, Prathyusha Bachali, Nan Shen, Kathryn M. Kingsmore, Robert D. Robl, Amrie C. Grammer, Shu Man Fu, Peter E. Lipsky
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPathologic inflammation is a major driver of kidney damage in lupus nephritis (LN), but the immune mechanisms of disease progression and risk factors for end organ damage are poorly understood.MethodsTo characterize molecular profiles thr
Externí odkaz:
https://doaj.org/article/bdee2886e9384d35ad8e4d6116f35089
Autor:
Kathryn M. Kingsmore, Prathyusha Bachali, Michelle D. Catalina, Andrea R. Daamen, Sarah E. Heuer, Robert D. Robl, Amrie C. Grammer, Peter E. Lipsky
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract To compare lupus pathogenesis in disparate tissues, we analyzed gene expression profiles of human discoid lupus erythematosus (DLE) and lupus nephritis (LN). We found common increases in myeloid cell-defining gene sets and decreases in genes
Externí odkaz:
https://doaj.org/article/9cae1bbe0654450f8dbce0fa0083bd35
Autor:
Robert D Robl, Amanda M Eudy, Prathyusha S Bachali, Jennifer L Rogers, Megan EB Clowse, David S Pisetsky, Peter E Lipsky
Publikováno v:
Clinical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f745f58d62832a5471f9fcad287d598
https://doi.org/10.1136/lupus-2022-lupus21century.45
https://doi.org/10.1136/lupus-2022-lupus21century.45
Autor:
Andrea R Daamen, Hongyang Wang, Prathyusha Bachali, Nan Shen, Kathryn M Kingsmore, Robert D Robl, Amrie C Grammer, Shu Man Fu, Peter E Lipsky
Publikováno v:
Lupus Nephritis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19c01ed54fa12c5a44639e1bda0b6937
https://doi.org/10.1136/lupus-2022-lupus21century.78
https://doi.org/10.1136/lupus-2022-lupus21century.78
Autor:
Robert D. Robl, Amanda M. Eudy, Prathyusha S. Bachali, Jennifer L. Rogers, Megan E.B. Clowse, David S. Pisetsky, Peter E. Lipsky
ObjectiveTo characterize the molecular landscape of patients with Type 1 and Type 2 systemic SLE erythematosus (SLE) by analyzing gene expression profiles from peripheral blood.MethodsFull transcriptomic RNA sequencing was carried out on whole blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90387291e6badbe9cff843d0f3f3e45
https://doi.org/10.1101/2022.11.19.22282527
https://doi.org/10.1101/2022.11.19.22282527
Autor:
Adam C. Labonte, Michelle D. Catalina, Peter E. Lipsky, James M. Dittman, Robert D. Robl, Hannah C. Ainsworth, Miranda C. Marion, Andrew Price, Kip D. Zimmerman, Bryce N. Aidukaitis, Timothy D. Howard, Katherine A. Owen, Carl D. Langefeld, Prathyusha Bachali, Amrie C. Grammer, Kathryn M. Kingsmore
Publikováno v:
Am J Hum Genet
Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder with a prominent genetic component. Individuals of African ancestry (AA) experience the disease more severely and with an increased co-morbidity burden compared to European ances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1480ca17d3eabcd883378dbabbb1c189
https://doi.org/10.1016/j.ajhg.2020.09.007
https://doi.org/10.1016/j.ajhg.2020.09.007
Autor:
Brittany A Martinez, Michelle D. Catalina, Kathryn M. Kingsmore, Sneha Shrotri, Andrea R. Daamen, Robert D. Robl, Sarah E Heuer, Amrie C. Grammer, Peter E. Lipsky, Prathyusha Bachali
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66e3c7569fb776eab467eb24f2d8e24
https://doi.org/10.1136/lupus-2021-lupus21century.13
https://doi.org/10.1136/lupus-2021-lupus21century.13
Autor:
Michelle D. Catalina, Amrie C. Grammer, Andrea R. Daamen, Sarah E. Heuer, Peter E. Lipsky, Kathryn M. Kingsmore, Robert D. Robl, Prathyusha Bachali
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports
Scientific Reports
To compare lupus pathogenesis in disparate tissues, we analyzed gene expression profiles of human discoid lupus erythematosus (DLE) and lupus nephritis (LN). We found common increases in myeloid cell-defining gene sets and decreases in genes controll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d730b5917cf632e7631fcaa3f5615cdc
https://doi.org/10.1038/s41598-021-93034-w
https://doi.org/10.1038/s41598-021-93034-w
Autor:
Erika L. Hubbard, Peter E. Lipsky, Prathyusha Bachali, Amrie C. Grammer, Sneha Shrotri, Kathryn M. Kingsmore, Katherine A. Owen, Adam C. Labonte, Robert D. Robl, Andrea R. Daamen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports
Scientific Reports
SARS-CoV2 is a previously uncharacterized coronavirus and causative agent of the COVID-19 pandemic. The host response to SARS-CoV2 has not yet been fully delineated, hampering a precise approach to therapy. To address this, we carried out a comprehen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfe548b61f0b6b952a718f5895681cd
https://doi.org/10.1038/s41598-021-86002-x
https://doi.org/10.1038/s41598-021-86002-x
Autor:
Michelle D. Catalina, Sarah E. Heuer, Robert D. Robl, Peter E. Lipsky, Amrie C. Grammer, Erika L. Hubbard, Nicholas S. Geraci, Prathyusha Bachali
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports
Scientific Reports
Arthritis is a common manifestation of systemic lupus erythematosus (SLE) yet understanding of the underlying pathogenic mechanisms remains incomplete. We, therefore, interrogated gene expression profiles of SLE synovium to gain insight into the natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661f83ab898ab1af4706ca91cf0afbaa
https://doi.org/10.1038/s41598-020-74391-4
https://doi.org/10.1038/s41598-020-74391-4